DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cubn and Cubn

DIOPT Version :9

Sequence 1:	NP_727348.2	Gene:	Cubn / 326235	FlyBaseID:	FBgn0052702	Length:	3750	Species:	Drosophila melanogaster
Sequence 2:	NP_001074553.1	Gene:	Cubn / 65969	MGIID:	1931256	Length:	3623	Species:	Mus musculus

Alignment Length:	3905	Identity:	1164/3905 - (29%)
Similarity:	1760/3905 - (45%)	Gaps:	548/3905 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 VNSPKIISKDGNLIFESGANRNISFRLSGNSRLTINEELDVMELLLATSGSKKRSGGKDDDFVDA 94
            ::.|::.:::|||:|.:.:.:||.||.....::.:|:: |:.|.|.....:|
Mouse    36 LHQPRMTTEEGNLVFLTSSAQNIEFRTGSLGKIKLNDD-DLGECLHQIQRNK------------- 86

  Fly    95 RELADQLADFNRRAFGANGLSAMLRVQQNRTRGSMALLRRFQTRLRALENRVDRMKTDLEANSCA 159
                |.:.|..|...|         :.||    .::.:.:..::|..||.....::.::|...|:
Mouse    87 ----DDIIDLKRNTTG---------LPQN----ILSQVHQLNSKLVDLERDFQSLQQNVERKVCS 134

  Fly   160 SGPCENGGTCYNTYTGFRCQCRSAFEGTKCEMDVNECALYEGTDLGCQNGGQCQNHFGTYSCLCQ 224
            |.||.|||||.|.:..|.|.|.|.::|..|..|||||.||.||..|||:|..|.|..|::.|.|.
Mouse   135 SNPCHNGGTCVNLHDSFICICPSQWKGLFCSEDVNECVLYAGTPFGCQSGSTCVNTMGSFRCDCT 199

  Fly   225 PGWHGMHCTQRKADCSQSSAWELCGHGSCVPSADD--------AGYRCICEPGWKT--NGLTPIC 279
            |..:|..|..:..||.|.|. :||.||.|    :|        ..:.|||:.||.|  ||::  |
Mouse   200 PDTYGPQCASKYNDCEQGSQ-QLCKHGIC----EDLQRVYHGQLRFNCICDAGWTTLPNGIS--C 257

  Fly   280 GEDVDECSDSAAHKPCS--TSCINLPGSFTCAPCPAGLTGNGVSCRDLDECQTNNGGCSLSPKVD 342
            .||.|||  |....|||  ..|.|..|||.|..||.|..|||..|:|::||:.||||||.:|.|.
Mouse   258 TEDKDEC--SLQPSPCSEHAQCFNTQGSFYCGACPKGWQGNGYQCQDINECEINNGGCSQAPLVP 320

  Fly   343 CINTYGSYHCGECPVGWTGDGRKCERSPQDIDIPAGQTPRTCPAGNNPCYPTASCFLISGTTS-- 405
            |:||.||:.||.||.|::||||.|  :|.||          |...|..|:|.|:|...|...|
Mouse   321 CLNTPGSFTCGNCPAGFSGDGRVC--TPLDI----------CSIHNGGCHPDATCSSSSVLGSLL 373

  Fly   406 --CRCPMGMVGTGYGPNGCVNGTTTNCKENPCLNGGICLFAGPSNYTCLCPIGFRPPICEPQPSP 468
              |.||.|..|.|||.||||. .:..|..:||:||. |: ...|:|.|.|..|:....|....:.
Mouse   374 PVCTCPPGYTGNGYGSNGCVR-LSNMCSRHPCVNGQ-CI-ETVSSYFCKCDSGWFGQNCTENINE 435

  Fly   469 CDQHPCKNGGRCRPTTSGDLFVCQCLPGYRGRLCETRFSSCNGMLSAQSGRLRYPPEGTGYEHNA 533
            |..:||.|||.|....:|  |.|.|...:.|..|:|..::|.|:||...|...|......|.||.
Mouse   436 CVSNPCLNGGTCIDGVNG--FTCDCTSSWTGYYCQTPQAACGGILSGTQGTFAYQSPNDTYVHNV 498

  Fly   534 QCAWVIRTNESLVVNVTFNSFDVEDSTECRFDWLQINDGRSAAAQIIGRYCGNHLPHGGNIVSSG 598
            .|.||:||:|..|:::||..||:|.::.|..::|||:||.|:|...:|||||:..|.|  :.||.
Mouse   499 NCFWVVRTDEEKVLHITFTFFDLESASNCPREYLQIHDGDSSADFPLGRYCGSTPPQG--VHSSA 561

  Fly   599 NQLYLWFRSDNSTAKEGFDLTWNSMEPQCGGRLNFETHGTLASPGSPGNYPKNRDCRWQLVAPTT 663
            |.||....|:......||...|.:..|:|||.|. ..:|::.|||.|||||..|||.|.|:....
Mouse   562 NSLYFHLYSEYIKRGRGFTARWEAKLPECGGILT-GNYGSITSPGYPGNYPPGRDCVWNLLVSPG 625

  Fly   664 KRIKLTFFSLQLEQHANCNFDYVLIKDSISGRE--LAKYCTTGAPAPLLLPTHLAEIHFHSDAEG 726
            ..|..||.:|.||.|.:|:.||:.|:|.....:  |.|:||:.:..||......|.||||||:|.
Mouse   626 SLITFTFGTLSLESHNDCSKDYLEIRDGPFHHDPILGKFCTSLSTPPLQTTGPAARIHFHSDSET 690

  Fly   727 SDTGFQLHYSVEERVPGCGGVYTAKEGTISESSTANTEPGGVSCEYEIHLAVGEQVVIQFARLEL 791
            ||.||.:.|........|||.||..||.:..............|.|.|....|||:||.|..:||
Mouse   691 SDKGFHITYLTTPSDLYCGGNYTDTEGELLLPPLTGPFSHSRQCVYLISQPQGEQIVINFTHVEL 755

  Fly   792 D-PLDCLEVLDITDEGGSILQEKICGSDASRLNPPTFTSE--FNRLKIKFYARAGSFQLNYRMAC 853
            : ...|........:..|:|: ||||::.  |.|....|.  :.||:|....:..||:.:|::||
Mouse   756 ESQRGCSHTFIEVGDHESLLR-KICGNET--LFPIRSISNNVWIRLRIDALVQKASFRADYQVAC 817

  Fly   854 DYKLNNEQGTITSPGYPNLTRSDRICTYTISTATNTVISLKRIDFQLTNGESDDDDNDECLTTNL 918
            ..:|..| |.|.||.|||.....|.|.:|||.....|:.|...|||:.:..|.|.|..|...:::
Mouse   818 GGELRGE-GVIRSPFYPNAYAGRRTCRWTISQPPREVVLLNFTDFQIGSSSSCDTDYIEIGPSSV 881

  Fly   919 RINDGLNRKILGPYCGKNQPEENFVSET-NYLQLHLSTDVDSMGRGF--KFEYRALATGNDKCGG 980
            ..:.| |.|    :||.|.|  :|::.. |.|.:..........|||  .|....|     :||.
Mouse   882 LGSPG-NEK----FCGTNIP--SFITSVYNVLYVTFVKSSSMENRGFMAMFSSEKL-----ECGK 934

  Fly   981 VHTRSGDHIRLPVHDDSYAGEATCYWVIMAPANKAIRLHWNSFSLENAVDCIYDYLEIYDSLGAQ 1045
            |.|.|...|..|.|.:.|.....|.|.|:....:.|||.::||.||...:|..||||:||:: ||
Mouse   935 VLTESTGIIESPGHPNVYPSGVNCTWHIVVQRGQLIRLVFSSFYLEFHYNCANDYLEVYDTI-AQ 998

  Fly  1046 VNDERSKPLAKYCGNSVPEDLLSHSRQLVLKFVSDYSESDGGFDLTYTFEDRAKCGGHIHASS-- 1108
            .:      |.:|||.|:|..|.|.|..:.|.||||.:.:..||.:.|.         .|:|||
Mouse   999 TS------LGRYCGKSIPPSLTSSSHSIKLIFVSDSALAHEGFSINYE---------AINASSVC 1048

  Fly  1109 --------GELTSPEYPANYSAGLDCDWHLTGTIDHLLEIQVENFELEQ--SPNCSADYLEVRNG 1163
                    |.|:||.:|.||....:|.:.:|..::..:.:...:|.||.  .|.| .|::|:|:|
Mouse  1049 LYDYTDNFGRLSSPNFPNNYPHNWNCVYRITVGLNQQIALHFTDFALEDYFGPKC-VDFVEIRDG 1112

  Fly  1164 GGTDSPLIGRFCGRDIPARIPGFSHEMRLILHTDSAINGRGFRLRWRIFAFGCGGSLRSNMGAIS 1228
            |...|||||.:||...|.||...|:::.|...:|:|:..|||...|...:.||||:|.:..|.::
Mouse  1113 GFETSPLIGIYCGSVFPPRIISHSNKLWLRFKSDTALTARGFSAYWDASSTGCGGNLTTPTGVLT 1177

  Fly  1229 SPRYPNSYPNMAHCEWRISLHPGSGISLLIEDLELEGLSNCYYDSVKIYTGIKLPNQSPCKVLCK 1293
            ||.||..|.:.:.|.||:....||...|..:|..||...||..|.:.::.| ...|......||.
Mouse  1178 SPNYPMPYYHSSECYWRLEASRGSPFLLEFQDFHLEHHPNCSLDYLAVFDG-PSTNSRLINKLCG 1241

  Fly  1294 DDDLHNPLIQLENNKGTIVFD--SDASNTFRGFRISYKANC--IRNLTATTGTIESLNYMEPFWE 1354
            |    .|...:.::|..::..  :||....|||.|:|:..|  :..:..|:|.:||:||..|:.:
Mouse  1242 D----TPPAPIRSSKDIVLLKLRTDAGQQGRGFEINYRQTCDNVVIVNKTSGILESINYPNPYDK 1302

  Fly  1355 TIPINCSWTIRAPKGNRV---LVEVSHLARHEQHVPTATMPGGLYIVD-----GRNVQEIVTPQA 1411
              ...|:|||:|..||.|   .:|..    .|.:|..:|  ..|.:.|     ||...|.:.|..
Mouse  1303 --DQRCNWTIQATTGNTVNYTFLEFD----VENYVNCST--DYLELYDGPQRIGRYCGENIPPPG 1359

  Fly  1412 MNISGEVLTVVH----NASNVNFQLDYRIDGCMEELRGTFGFFQSPNYPKMYPNNLECYWLITVE 1472
            .....:::.|.|    ::....|::.:.|.||..|:.||.|.|.||.||..||:|.||.|.|.|.
Mouse  1360 ATTGSKLIVVFHTDGVDSGEKGFKMHWFIHGCGGEMSGTMGSFSSPGYPNSYPHNKECIWNIRVA 1424

  Fly  1473 QDSAIELTINNIDLEDSPNCTKDALTVSNHKNSVEVHE----RHCG---STTKLVITSSGHRLHV 1530
            ..::|:|||::.|:|...:|..|.|.:   ...::.|.    :.|.   |...:.|:|:.:.|.:
Mouse  1425 PGNSIQLTIHDFDVEYHASCKYDTLEI---YTGLDFHSPRIAQLCSRSPSANPMQISSTDNELAI 1486

  Fly  1531 RFISDNSHNGLGFEATYRTVKATCGGKLTARNGVIESPNYPLNYPAHSRCEWQVEVSQHHQIVFE 1595
            ||.:|:|.||.||.|::|.|...|||......|.|.|||||.||.|::.|.|.::|.::|:::..
Mouse  1487 RFKTDSSLNGRGFNASWRAVPGGCGGIFQVSRGEIHSPNYPNNYRANTECSWIIQVEKYHRVLLN 1551

  Fly  1596 MADLNLESGYDCNWDYLEAYDLTEDDTEGERLFKVCGDETEDDKLLSSSSNMAVVRFISDDSVSK 1660
            :.|.:||:...|    |..||  ...:...|:..|||.: :....::||.|...|||.|..|...
Mouse  1552 ITDFDLEATDSC----LMTYD--GSSSANTRVATVCGRQ-QPPNSITSSGNSLFVRFQSGSSSQS 1609

  Fly  1661 KGFRLHFHESCGQTIIVDETMFDYIQMSRQAA---RNESCLWVFQAVEPNKRIIFTPTHVKLRED 1722
            :|||..|.:.||..||.|.:  |.|......|   .|::|.|:.:|..|...|..:.||..|:..
Mouse  1610 RGFRAQFRQECGAHIITDSS--DSISSPLYPANYPNNQNCTWIIEAQPPFNHIALSFTHFHLQSS 1672

  Fly  1723 ANQQYPTEGDCLNVGVKIYEGTEPQGTPRLKFC-RSHPPALISNGQALTVSVPLQLVEEFQGH-- 1784
            .        ||....|:|.:|.:.....:.::| .|.|..:||.|.||||......|..|.|.
Mouse  1673 T--------DCTRDFVEILDGRDSDAPVQGRYCGTSLPHPIISFGNALTVRFVSDSVYGFDGFHA 1729

  Fly  1785 -YMTMDTSCGSIYNALSGKFTSPYYPASYPPNIECLWLLEASMGNSLSLTLESMDLEKSESCNRD 1848
             |....::||..:....|.|.||.||..|..|.||:|.:.:|.||.|.|:..|..||.|.:||:|
Mouse  1730 IYSASTSACGGTFYTGDGIFNSPGYPEDYHSNTECVWNIASSPGNHLQLSFLSFQLENSLNCNKD 1794

  Fly  1849 YLEVREESESGQLIGVYCGNEVPGVIHSRGA--IWMKFKSDDDNVGEGFMASY-NYEHHNELNGT 1910
            ::|:||.:.:|.|:|.||||.:||...|...  :|::|.||....|.||.|.: |...::.:.||
Mouse  1795 FVEIREGNATGHLMGRYCGNSLPGNYSSIEGHNLWVRFVSDGSGTGMGFQARFKNIFGNDNIVGT 1859

  Fly  1911 EGTIESPHFPSKFQDPVPYSWRITVDKEYVVAISLLYLRDLD------QPHLNFYDGYSDIGARI 1969
            .|.|.:|.:|..:.....|.|.:.||..:::...:|.: |::      ...|..|||: ||.:|:
Mouse  1860 HGKIATPFWPGNYPLNSNYRWTVNVDSSHIIHGRILEM-DIELTTNCFYDSLKIYDGF-DIHSRL 1922

  Fly  1970 EVT---DPDETIISSTNVVYF-------TSNRGPFKLNWNRLSKEALRSNRTAEE-RTRQCGNQL 2023
            ..|   ...|:..||.|.:.|       .|.|| |.|.|..:..    ||.|... ....||..:
Mouse  1923 IGTYCGTQRESFSSSRNSLTFQFSSDSSKSGRG-FLLEWFAVDV----SNVTLPTIAPGACGGYM 1982

  Fly  2024 ITIDRSVIGFHSPGYPNGYEQDLNCFWTLVPSNPAMHAVLTLSQIDLEIFSED------CIADYV 2082
            :|.|..|. |.|||:|..|....:|.|.:...:         |.::|.|.|.|      |..|.:
Mouse  1983 VTGDTPVF-FFSPGWPGPYGNGADCIWIIYAPD---------STVELNILSMDIEAQLSCSYDKL 2037

  Fly  2083 KIFSGSDLQNWSELRTLCSL----PTESSDRVFHGRPYLRVEFVTDPSVNKTGFNGIVRTACGSE 2143
            .|..| |.:...:|..||..    |..|:..      |:.:.|.:|.||...|||...:.:||..
Mouse  2038 IIKDG-DSRLSQQLAVLCGRSVPGPIRSTGE------YMYIRFTSDGSVTGAGFNASFQKSCGGY 2095

  Fly  2144 ITASKGLVNITEILKVLPR------PNHDCVWTIKVRQGRRIKIDFPD-FQLQNNMASGSSDCRN 2201
            :.|.:|::       ..|:      ||.:|.|.:.|:.|..|.:.|.. ||:||..:|.|..  :
Mouse  2096 LHADRGII-------TSPKYPDNYLPNLNCSWHVLVQSGLTIAVHFEQPFQIQNRDSSCSQG--D 2151

  Fly  2202 YLLLRNGNDEDSPFL----GRGKYCEDVVHEVLNTSSNKAYIKFHFASPPRFLVS---------- 2252
            ||:||||.|..||.|    |.|::|.......|.||.|:.:|:|         :|
Mouse  2152 YLVLRNGPDNHSPPLGPSGGNGRFCGIYTPSTLFTSDNEMFIQF---------ISDNSNGGQGFK 2207

  Fly  2253 FRFEELRYTDSGRIRLSASGDEQFISSPYYPHLPHPHSECIWIVEAPPEHRIMLHFQGAFDMLDA 2317
            .|:|.......|.|.:..:..:.:::||.||.....|:|||||:|||....|.|.|:..|::
Mouse  2208 IRYEAKSLACGGTIYIHDANSDGYVTSPNYPANYPQHAECIWILEAPSGRSIQLQFEDQFNI--- 2269

  Fly  2318 TGEPEECQREFVLINDGSTELRPEIGRYCGNRKPDTIYSTGNQMRIRYFTDVSEPHMGFNASLSV 2382
             .|...|...::.:.||:....|.:.:.||:..|....|:...|.:::.|:....:|||.|..|:
Mouse  2270 -EETPNCSASYLELRDGANSNAPVLSKLCGHTLPRNWVSSRGLMYLKFHTEGGSGYMGFKAKYSI 2333

  Fly  2383 ARCGGSFHSPEGVIAS---PSRDLLLIHEEGKQLQECVYTIELEKGSTIDLTSEYLQIP----TL 2440
            ..|||:.....|||.|   |:|    ::...   ..|.:.|:       .|...||.|.    .|
Mouse  2334 VSCGGTVSGDSGVIESVGYPTR----LYANN---VFCQWHIQ-------GLPGHYLTIRFEDFNL 2384

  Fly  2441 RNGSCSQRNHLMLEEMDAFGLDGEEKIVDTLM--LCGMEAKHLISETNKIVFRYRFLDGIPAENQ 2503
            ::.....::.:.:.|....|:         |:  .||......: :|:..|...||:......:.
Mouse  2385 QSSPGCAKDFVEIWENHTSGI---------LLGRYCGNSIPSSV-DTSSNVASIRFVTDGSVTDS 2439

  Fly  2504 GFRLKYTSLGSRCGETIYASVGVLQTPGYPLGVPHPMHCKWQVQVPKGRRVRLEI--LDFNTGTN 2566
            ||||::.|....||..::...|...:|.||...|||..|:|.:.|.:||::.|..  |..:|..:
Mouse  2440 GFRLQFKSSREVCGGDLHGPTGTFTSPNYPNPNPHPRICEWTINVHEGRQIILTFTNLRLSTQQS 2504

  Fly  2567 MDLRGRLGFRGRLTVANDFKMQSILGRYNVDPPAEVLSSDNTMGIDAF----------------- 2614
            .:....:.|.|...  |..::|.:..|.||  ..|..||.|||.:..|
Mouse  2505 CNTEHLIVFNGIRN--NSPRLQKLCSRVNV--TNEFKSSGNTMKVIFFTDGSRPYGGFTASYTSS 2565

  Fly  2615 -------LLPIVQNHGIKLRFSAYGSSSCPGFTVMMNEVADIQFQRFNISRPLHCSYKVVPPS-- 2670
                   .||.|..          |:.|.||:    |.:.|       .:|.|.|.:.:..|:
Mouse  2566 EDAVCGGTLPSVSG----------GNFSSPGY----NGIRD-------YARNLDCEWTLSNPNRE 2609

  Fly  2671 NSTLLIRVKEYNTTSVMMWNTHMCALLSPLKFNRLEQEEELMERILCDYQSPAPGKPLPSIRLPF 2735
            ||::.|.....:..|      |.......|:|.....:..|:|: .|...:|.    :|.: :|:
Mouse  2610 NSSISIHFLGLSLES------HQDCTFDVLEFRVGNADGPLIEK-FCSLSAPR----VPLV-IPY 2662

  Fly  2736 P-IQLVVSASARNAMTNLVLSYSTQSCGGVIILEPGDNMTVHQPSGMVSAAGAIDCAWAI-GPYT 2798
            | :.:...::.|...|...:.||..:|||:   :.|:|..:..|:.....:....|:|.: .|
Mouse  2663 PQVWIHFVSNERVEYTGFYVEYSFTNCGGI---QTGENGVISSPNYPNLYSRWTQCSWLLEAP-- 2722

  Fly  2799 DASGEDEVLVPQDIQLEVSVYNVNLPAPSPSAQSPEAPCLHHYLKVYNGPDQNSPSLGLFCNQA- 2862
              .|....|...|..:|      |.|.           |....:.|.||....||.:|.:|.|:
Mouse  2723 --EGHTITLTFSDFSVE------NHPT-----------CTSDSVTVRNGDSPGSPIIGRYCGQSV 2768

  Fly  2863 -----TAVNMVV----------ERGLFLEYHSDSFSANATFNVSIKYGSGCGGKLVYPYRAI--- 2909
                 :..|.:|          .||.:           ||:|.:.   .||||.|......|
Mouse  2769 PGPIQSGSNQLVVTFNTNNQGQSRGFY-----------ATWNTNT---LGCGGTLHSDNGTIKSP 2819

  Fly  2910 DFAEQYKNNVECIWEVEATMGYHIGLTFQGRFYIEDSPG-CTKDYLLVQQRNETTGNWTDLQRIC 2973
            .:.:.:..|..|.|........|..::|...|.|..|.. |...::.|.:....| |...|...|
Mouse  2820 HWPQTFPENSRCSWTAVTHESKHWEISFDSNFRIPSSDSQCRNSFVKVWEGMLET-NDALLATSC 2883

  Fly  2974 GRVAPEMINTTSPYLRLIFRSDGDVVADGFLAKFERNCGGLLYADSTEQELASPGFPNGYEKYLQ 3038
            |.|||..|.|.......:|:|: ::.|.||.|.|...||...  :|:..::.||.||..|:..:.
Mouse  2884 GNVAPSPIVTLGNIFTAVFQSE-EMPAQGFSASFISRCGRTF--NSSTGDIVSPNFPKHYDNNMN 2945

  Fly  3039 CNWTIVPRSPSMGGVLVSFVNFDLE-QGPIS-VCLYDNLTVTTKDKGKDPQQT---TLCGVKHNH 3098
            ||:.|.....|:  |:::||:|.|| :..:| .|.||.|.:.   ||.:...|   |:||.:...
Mouse  2946 CNYYIDVAPQSL--VILTFVSFHLEDRSAVSGTCDYDGLHII---KGHNLSSTPLVTICGSETLR 3005

  Fly  3099 EYRGKEYVNLLLRTDGSYSGRGFTLLYTSRLCGGIISRTSMVESPVQHTDNTLPPGSDCYWNLTA 3163
            .......|.|...:|...:..||.:.|....||||.|.|..|.:....:....|....|.::|..
Mouse  3006 PLTIDGPVMLNFYSDAYITDFGFKISYRVANCGGIYSGTYGVLNSPSFSYTNYPNNVYCVYSLQV 3070

  Fly  3164 PAGYKFNIKFLFIDFEANSNCAYDGVEVFSGPIPDERYRWGRFCGRINEDLPLISIPQERGIIHS 3228
            .......::|...:...::.|::|.:|||.||....| ..|:|||   ..||.:.......:...
Mouse  3071 RNDRLILLRFNDFEIVPSNLCSHDYLEVFDGPSIGNR-SIGKFCG---STLPQVIKSTNNSLTLL 3131

  Fly  3229 F-SDDRDPSRG----FRALVRVMPNCDEKISLNGSSRYVYSKFNNAGGYQNDLDCQIVFRVNPDQ 3288
            | :|....:||    ||..:.....|...:: ..|..:|....::.|.|...|:| |.:.:.|:.
Mouse  3132 FKTDSSQTARGWKVSFRETIGPQQGCGGYLT-EDSKSFVSPDHDSDGLYDKGLNC-IWYIIAPEN 3194

  Fly  3289 Q-ISVEFSNFHVQDTDG---CRSDYVELRDGGGTFADIIGRFCGQNQPPTLRTTRHTLYMRFVTD 3349
            : :.:.|:.|.:::...   |..|||::.||....:.:.|||||.::|....::.:.|.::||:|
Mouse  3195 KLVKLTFNAFTLEEPSSPGKCTFDYVQIADGASINSYLGGRFCGSSRPAPFISSGNFLTVQFVSD 3259

  Fly  3350 NKVTDTGFQVTINAIPRLCGSSEITLSADGTKEVTINSPARTPGGNYPN----GVSCFWKIKGDS 3410
            ..:...||..|...:...||         ||...| :.|..|......|    ..:|.|.|:...
Mouse  3260 ISIQMRGFNATYTFVDMPCG---------GTYNAT-SMPQNTSSPQLSNIRRPFSTCTWVIEAPP 3314

  Fly  3411 LLRVQFVNFDLHGPNQNGSCVDDYLKIYNSEDAPLLEQGLGTDLVFNGQTSSKNGFGFATEHVYC 3475
            ..:||...:.|..|:|:  |....|::.:||..             ||...::          :|
Mouse  3315 HQQVQITVWKLQLPSQD--CSRSSLELQDSEQT-------------NGNQVTQ----------FC 3354

  Fly  3476 G---NVKPDIYYGRSSEVYLKFRSKGLEQHG--GFQLQVALNSNRERHYDGLQGRVH-------L 3528
            |   ...| ::|...|...:.|:|..|.::.  .|..::| :.|||  |:...|.:.       .
Mouse  3355 GANYTTLP-VFYSSGSTAVVVFKSDFLNRNSRVHFTYEIA-DCNRE--YNQAFGNLKSPGWPQGY 3415

  Fly  3529 SQSADCNIIIRAPPNYTLSL-YYTELIFGTYDCEMENLEVFDRTNRS---LQRVCSFVDMGKSLF 3589
            :.:.||:||:|||.|:.:|| :|...:..:..|..:.|||.:.::.|   |.:.||.: :...:|
Mouse  3416 ANNLDCSIILRAPQNHRISLFFYWFQLEDSRQCMNDFLEVRNGSSSSSPLLGKYCSNL-LPNPIF 3479

  Fly  3590 SNANELRLQMKTGSYLT--SLDLTYLASPVEKGPGCGGQFYNTEGIFSNPFYPNNVRNNSECQWI 3652
            |.:|||.|...:....|  ..::.:.:||.    ||||.....|||.:||.:|::..||:.|:|.
Mouse  3480 SQSNELYLHFHSDDSDTHHGYEIIWASSPT----GCGGTLLGNEGILANPGFPDSYPNNTHCEWT 3540

  Fly  3653 VRVPSNNVVFLTFEVFNLGSKTTCHTDYLQILEQDATGEEREMRRFCGEDN---PKYYKSRRSQV 3714
            :..||...:.:.|...::.|...|..:|| ||.............|||.|.   |.:..|.|  |
Mouse  3541 IVAPSGRPLSVGFPFLSIDSPGGCDQNYL-ILFNGPDANSPPFGPFCGIDTVVAPFHASSNR--V 3602

  Fly  3715 LVRFH 3719
            .:|||
Mouse  3603 FIRFH 3607

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cubn	NP_727348.2	EGF_CA	156..190	CDD:238011	15/33 (45%)
		EGF_CA	192..233	CDD:238011	20/40 (50%)
		EGF_CA	282..322	CDD:214542	20/41 (49%)
		EGF_3	328..366	CDD:289699	23/37 (62%)
		EGF	430..457	CDD:278437	10/26 (38%)
		EGF_CA	469..503	CDD:238011	12/33 (36%)
		CUB	509..622	CDD:238001	45/112 (40%)
		CUB	627..737	CDD:238001	49/111 (44%)
		CUB	744..849	CDD:294042	33/107 (31%)
		CUB	853..970	CDD:238001	38/119 (32%)
		CUB	978..1094	CDD:238001	45/115 (39%)
		CUB	1100..1211	CDD:238001	41/122 (34%)
		CUB	1216..1330	CDD:238001	36/115 (31%)
		CUB	1446..1549	CDD:238001	39/109 (36%)
		CUB	1554..1667	CDD:238001	39/112 (35%)
		CUB	1792..1899	CDD:238001	46/108 (43%)
		CUB	1910..1998	CDD:294042	29/103 (28%)
		CUB	2019..2133	CDD:238001	34/123 (28%)
		CUB	2140..2242	CDD:238001	37/112 (33%)
		CUB	2263..2379	CDD:238001	33/115 (29%)
		CUB	2385..2511	CDD:238001	29/134 (22%)
		CUB	2516..2630	CDD:238001	34/139 (24%)
		CUB	<2833..2892	CDD:294042	16/74 (22%)
		CUB	2898..3008	CDD:238001	31/113 (27%)
		CUB	3011..3127	CDD:238001	35/120 (29%)
		CUB	3130..3241	CDD:238001	30/115 (26%)
		CUB	3254..3363	CDD:238001	29/112 (26%)
		CUB	3379..3508	CDD:238001	29/137 (21%)
		CUB	3531..3601	CDD:294042	25/73 (34%)
		CUB	3623..3733	CDD:238001	33/100 (33%)
Cubn	NP_001074553.1	Interaction with AMN. /evidence=ECO:0000250\|UniProtKB:O60494	39..46		1/6 (17%)
		EGF_CA	133..164	CDD:238011	4/30 (13%)
		EGF_CA	167..207	CDD:238011	21/39 (54%)
		EGF_CA	260..301	CDD:214542	16/50 (32%)
		EGF_3	306..344	CDD:289699	21/37 (57%)
		EGF_3	350..387	CDD:289699	17/36 (47%)
		EGF_CA	400..430	CDD:238011	15/33 (45%)
		EGF_CA	432..468	CDD:238011	11/35 (31%)
		CUB	474..585	CDD:238001	43/110 (39%)
		CUB	590..699	CDD:238001	44/108 (41%)
		CUB	708..815	CDD:238001	35/107 (33%)
		CUB	817..927	CDD:238001	38/111 (34%)
		CUB	932..1041	CDD:238001	33/111 (30%)
		CUB	1052..1158	CDD:238001	33/117 (28%)
		CUB	1165..1275	CDD:238001	42/109 (39%)
		CUB	1278..1388	CDD:238001	32/116 (28%)
		CUB	1391..1505	CDD:238001	40/122 (33%)
		CUB	1510..1599	CDD:238001	34/95 (36%)
		CUB	1620..1733	CDD:238001	35/115 (30%)
		CUB	1738..1847	CDD:238001	39/112 (35%)
		CUB	1859..1962	CDD:238001	33/111 (30%)
		CUB	1978..2089	CDD:238001	35/127 (28%)
		CUB	2092..2212	CDD:238001	36/130 (28%)
		CUB	2217..2333	CDD:238001	36/129 (28%)
		CUB	2336..2447	CDD:238001	29/117 (25%)
		CUB	2452..2564	CDD:238001	29/113 (26%)
		CUB	2570..2686	CDD:238001	30/141 (21%)
		CUB	2689..2800	CDD:238001	23/111 (21%)
		CUB	2805..2918	CDD:238001	28/131 (21%)
		CUB	2920..3034	CDD:238001	31/114 (27%)
		CUB	3037..3148	CDD:238001	35/115 (30%)
		CUB	3157..3273	CDD:238001	27/120 (23%)
		CUB	3278..3392	CDD:238001	31/117 (26%)
		CUB	3395..3506	CDD:238001	23/117 (20%)
		CUB	3511..3623	CDD:238001	34/124 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	97	1.000	Domainoid score	I7263
eggNOG	1	0.900	-	-		E1_KOG4292
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37434
Inparanoid	1	1.050	1472	1.000	Inparanoid score	I109
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46457
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006182
OrthoInspector	1	1.000	-	-		otm43532
orthoMCL	1	0.900	-	-		OOG6_106358
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5821
SonicParanoid	1	1.000	-	-		X4462
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.760