DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cubn and tll2l

DIOPT Version :9

Sequence 1:NP_727348.2 Gene:Cubn / 326235 FlyBaseID:FBgn0052702 Length:3750 Species:Drosophila melanogaster
Sequence 2:NP_001016661.1 Gene:tll2l / 549415 XenbaseID:XB-GENE-478930 Length:500 Species:Xenopus tropicalis


Alignment Length:236 Identity:73/236 - (30%)
Similarity:115/236 - (48%) Gaps:9/236 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly  1434 YRIDGCMEELRGTFGFFQSPNYPKMYPNNLECYWLITVEQDSAIELTINNIDLEDSPNCTKDALT 1498
            |..|.|...|....|...||:||..||:|..|.|||.:..:. :.:......|:.|.||..|.:.
 Frog   266 YNCDVCSTLLSDVNGTLFSPSYPSAYPDNANCVWLIRIPSNQ-VSVQFIAFSLQTSQNCVSDYVK 329

  Fly  1499 VSN--HKNSVEVHERHCGSTTKLVITSSGHRLHVRFISDNSHNGLGFEATYRTVKATCGGKLTAR 1561
            :.:  .::...:.::.|||.....||:|.:.:.:.|:|:..:...||||||.||  :|||..|::
 Frog   330 IYDGATRSDPVLLDKACGSLLLPPITASSNLMLLEFVSNEGNTMTGFEATYSTV--SCGGTYTSQ 392

  Fly  1562 NGVIESPNYPLNYPAHSRCEWQVEVSQHHQIVFEMADLNLESGYDCNWDYLEAYDLTEDDTEGER 1626
            :....||.||:.||..:.|.|.:......:||..:..:.:|.|..|.:|.|..||  ..:|....
 Frog   393 SNSFSSPGYPVAYPPLTTCIWSIYAPVGFKIVLTINKIEVEYGLLCMYDSLTIYD--GYNTTAPI 455

  Fly  1627 LFKVCGDETEDDKLLSSSSNMAVVRFISDDSVSKKGFRLHF 1667
            |...||:....:::....|.:.|  |.||.||.||||:..:
 Frog   456 LRCACGNTAVPNQISRGRSMLLV--FSSDISVQKKGFQASY 494

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CubnNP_727348.2 EGF_CA 156..190 CDD:238011
EGF_CA 192..233 CDD:238011
EGF_CA 282..322 CDD:214542
EGF_3 328..366 CDD:289699
EGF 430..457 CDD:278437
EGF_CA 469..503 CDD:238011
CUB 509..622 CDD:238001
CUB 627..737 CDD:238001
CUB 744..849 CDD:294042
CUB 853..970 CDD:238001
CUB 978..1094 CDD:238001
CUB 1100..1211 CDD:238001
CUB 1216..1330 CDD:238001
CUB 1446..1549 CDD:238001 31/104 (30%)
CUB 1554..1667 CDD:238001 36/112 (32%)
CUB 1792..1899 CDD:238001
CUB 1910..1998 CDD:294042
CUB 2019..2133 CDD:238001
CUB 2140..2242 CDD:238001
CUB 2263..2379 CDD:238001
CUB 2385..2511 CDD:238001
CUB 2516..2630 CDD:238001
CUB <2833..2892 CDD:294042
CUB 2898..3008 CDD:238001
CUB 3011..3127 CDD:238001
CUB 3130..3241 CDD:238001
CUB 3254..3363 CDD:238001
CUB 3379..3508 CDD:238001
CUB 3531..3601 CDD:294042
CUB 3623..3733 CDD:238001
tll2lNP_001016661.1 ZnMc_hatching_enzyme 86..268 CDD:239810 1/1 (100%)
CUB 272..382 CDD:238001 32/110 (29%)
CUB 385..495 CDD:238001 36/114 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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