DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Cubn and CG6763

DIOPT Version :9

Sequence 1:NP_727348.2 Gene:Cubn / 326235 FlyBaseID:FBgn0052702 Length:3750 Species:Drosophila melanogaster
Sequence 2:NP_001262871.1 Gene:CG6763 / 42754 FlyBaseID:FBgn0039069 Length:354 Species:Drosophila melanogaster


Alignment Length:380 Identity:76/380 - (20%)
Similarity:120/380 - (31%) Gaps:141/380 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly  1266 LSNCY------YDSVKIYTGIKLPNQSPCKV---LCKDDDLHNPLIQLENNKGTIVFDS-DASNT 1320
            ||:|.      ||.|.....|:||.....::   |.||.....||       ||.:|.. |...|
  Fly    13 LSSCQALPYVSYDDVDDTEVIELPGNGIEEIPPTLGKDIIDLTPL-------GTALFGKPDEELT 70

  Fly  1321 FRGFRISYKANCIRNLTATTGTI--ESL-NYMEPFWETIPINCSWTIRAPKGNRVLVEVSHLARH 1382
                     ||.:.|.:|....:  |.| :|:|                  |:.::.:...:.::
  Fly    71 ---------ANRVGNFSADADEMNPEELGSYLE------------------GDMLVPQTDLIMKN 108

  Fly  1383 EQHVPTATMPGGL--YIVDGR-NVQEIVTPQAMNISGEVLTVVHNASNVNF-----QLDY----- 1434
            .....::..|.|:  |.:.|. |.:::.|.:  |..||    .|..:.:.|     :.||     
  Fly   109 GLPTQSSRWPNGVVPYEIRGNFNARDMATIE--NAIGE----YHRRTCIRFVKRSSERDYISIRG 167

  Fly  1435 ----------RIDG-----------------CMEELRGTFGFFQSPNYPKMYPNNLECYWLITVE 1472
                      |:.|                 .|.||....||....|               .:|
  Fly   168 DNSGCWSSVGRVGGKQEVNLQSPGCLSRPGTAMHELMHALGFLHEQN---------------RME 217

  Fly  1473 QDSAIELTINNIDLEDSPNCTKDALT------------VSNHKNSVEVHERHCGSTTKLVITSSG 1525
            :|..:.:..||:......|..|.|.|            :...||:..::    |..|.|.:.::|
  Fly   218 RDGYVAIQYNNVQSSAMNNFEKAARTEAFGVPYDYGSVMHYSKNAFSIN----GQPTILAMQANG 278

  Fly  1526 HRLHVRFISDNSHNGLGFEATYRTVKAT----CGGKLTARNGVIESPNYPLNYPA 1576
                    :|......|| :.|...|..    ||    ..|.|..:|..|...||
  Fly   279 --------ADKMGQRNGF-SDYDIQKLNRMYDCG----TVNAVPVAPGLPAPAPA 320

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CubnNP_727348.2 EGF_CA 156..190 CDD:238011
EGF_CA 192..233 CDD:238011
EGF_CA 282..322 CDD:214542
EGF_3 328..366 CDD:289699
EGF 430..457 CDD:278437
EGF_CA 469..503 CDD:238011
CUB 509..622 CDD:238001
CUB 627..737 CDD:238001
CUB 744..849 CDD:294042
CUB 853..970 CDD:238001
CUB 978..1094 CDD:238001
CUB 1100..1211 CDD:238001
CUB 1216..1330 CDD:238001 19/73 (26%)
CUB 1446..1549 CDD:238001 21/114 (18%)
CUB 1554..1667 CDD:238001 8/23 (35%)
CUB 1792..1899 CDD:238001
CUB 1910..1998 CDD:294042
CUB 2019..2133 CDD:238001
CUB 2140..2242 CDD:238001
CUB 2263..2379 CDD:238001
CUB 2385..2511 CDD:238001
CUB 2516..2630 CDD:238001
CUB <2833..2892 CDD:294042
CUB 2898..3008 CDD:238001
CUB 3011..3127 CDD:238001
CUB 3130..3241 CDD:238001
CUB 3254..3363 CDD:238001
CUB 3379..3508 CDD:238001
CUB 3531..3601 CDD:294042
CUB 3623..3733 CDD:238001
CG6763NP_001262871.1 Astacin 116..304 CDD:279708 42/225 (19%)
ZnMc_astacin_like 119..300 CDD:239807 39/214 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45444889
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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