Protein Alignment Cubn and CDCP2

DIOPT Version :9

• Sequence 1: NP_727348.2
• Gene: Cubn / 326235
• FlyBaseID: FBgn0052702
• Length: 3750
• Species: Drosophila melanogaster
• Sequence 2: NP_001340584.1
• Gene: CDCP2 / 200008
• HGNCID: 27297
• Length: 540
• Species: Homo sapiens
• Alignment Length: 393
• Identity: 113/393 - (28%)
• Similarity: 179/393 - (45%)
• Gaps: 44/393 - (11%)

  Fly   960 MGRGFKFEYRALATGNDKCGGVHTRSGDHIRLPVHDDSYAGEATCYWVIMAPANKAIRLHWNSFS 1024
            :|.|.    :|.|....|||||.:....:...|.....|.....|.|:|:.....::.|.:::|.
Human    16 LGPGL----QAQAMEGVKCGGVLSAPSGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTFHAFD 76

  Fly  1025 LENAVDCIYDYLEIYDSLGAQVNDERSKPLAKYCGNSVPEDLLSHSRQLVLKFVSDYSESDGGFD 1089
            ||....|.:|:||||:  ||  :.::...|.::||...|....|....:.:.|.||...:..||.
Human    77 LEYHDTCSFDFLEIYN--GA--SPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVASHGFS 137

  Fly  1090 LTYTFEDRAKCGGHIHASSGELTSPEYPANYSAGLDCDWHLTGTIDHLLEIQVENFELEQSPNCS 1154
            ..|   .:..|||.:...||.|||||||.||...::|.|.:.......:::...:|::|.:..|:
Human   138 AGY---QKDVCGGVLTGLSGVLTSPEYPNNYPNSMECHWVIRAAGPAHVKLVFVDFQVEGNEECT 199

  Fly  1155 ADYLEVRNGGGTDSPLIG-RFCGRDIPARIPGFSHEMRLILHTDSAINGRGFRLRWRIFAFGCGG 1218
            .||:.|..|.|   |..| .:||...|..:....||::::..:|..|.||||:..:  |:..|..
Human   200 YDYVAVLGGPG---PTRGHHYCGSTRPPTLVSLGHELQVVFKSDFNIGGRGFKAYY--FSGECQE 259

  Fly  1219 SLRSNMGAISSPRYPNSYPNMAHCEWRISLHPGSGISLLIEDLELEG----LSNCYYDSVKIYTG 1279
            ...:..|..|||:||:||||...|.|.|.|.||..:.:...||:||.    ...|.:|.:..:.|
Human   260 VYMAMRGNFSSPQYPSSYPNNIRCHWTIRLPPGYQVKVFFLDLDLEEPNSLTKTCDFDHLAAFDG 324

  Fly  1280 IKLPNQSPCKVLCKDDDLHN-------PLIQLENNKGTIVFDSDASNTFRGFRISY------KAN 1331
            ..  .::|.        |.|       |.:...:|:..::..:|.|.|.|||.::|      ..:
Human   325 AS--EEAPL--------LGNWCGHHLPPPVTSSHNQLLLLLHTDRSTTRRGFSVAYIGVVPMNVS 379

  Fly  1332 CIR 1334
            |.|
Human   380 CSR 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cubn	NP_727348.2	EGF_CA	156..190	CDD:238011
		EGF_CA	192..233	CDD:238011
		EGF_CA	282..322	CDD:214542
		EGF_3	328..366	CDD:289699
		EGF	430..457	CDD:278437
		EGF_CA	469..503	CDD:238011
		CUB	509..622	CDD:238001
		CUB	627..737	CDD:238001
		CUB	744..849	CDD:294042
		CUB	853..970	CDD:238001	2/9 (22%)
		CUB	978..1094	CDD:238001	32/115 (28%)
		CUB	1100..1211	CDD:238001	37/111 (33%)
		CUB	1216..1330	CDD:238001	36/130 (28%)
		CUB	1446..1549	CDD:238001
		CUB	1554..1667	CDD:238001
		CUB	1792..1899	CDD:238001
		CUB	1910..1998	CDD:294042
		CUB	2019..2133	CDD:238001
		CUB	2140..2242	CDD:238001
		CUB	2263..2379	CDD:238001
		CUB	2385..2511	CDD:238001
		CUB	2516..2630	CDD:238001
		CUB	<2833..2892	CDD:294042
		CUB	2898..3008	CDD:238001
		CUB	3011..3127	CDD:238001
		CUB	3130..3241	CDD:238001
		CUB	3254..3363	CDD:238001
		CUB	3379..3508	CDD:238001
		CUB	3531..3601	CDD:294042
		CUB	3623..3733	CDD:238001
CDCP2	NP_001340584.1	CUB	30..141	CDD:238001	32/117 (27%)
		CUB	145..254	CDD:238001	37/113 (33%)
		CUB	257..370	CDD:278839	35/122 (29%)
		Zona_pellucida	380..>463	CDD:332579	2/3 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D4105at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920