DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cubn and neto1l

DIOPT Version :9

Sequence 1:NP_727348.2 Gene:Cubn / 326235 FlyBaseID:FBgn0052702 Length:3750 Species:Drosophila melanogaster
Sequence 2:XP_021325973.1 Gene:neto1l / 100331363 ZFINID:ZDB-GENE-091207-1 Length:548 Species:Danio rerio


Alignment Length:565 Identity:129/565 - (22%)
Similarity:198/565 - (35%) Gaps:153/565 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly  1792 CGS-IYNALSGKFTSPYYPASYPPNIECLWLLEASMGNSLSLTL-ESMDLEKSESCNRDYLEVRE 1854
            ||: :.....|.||||.||..|||..||::::||.....:.|.. |...:|.|..|..|::|||:
Zfish    40 CGTWVKEPEGGLFTSPNYPNKYPPERECIYIIEAPPRQCIDLFFDEKYSIEPSWECKFDHIEVRD 104

  Fly  1855 ESES-GQLIGVYCGNEVPGVIHSRGA-IWMKFKSDDDNVGEGFMASYNYEH-------------- 1903
            .... ..:||.|||.:.|..|.|.|. :|:||.:|.:....||.||||:..              
Zfish   105 GPFGFSPIIGRYCGQQNPPYIRSSGRYLWIKFVADGELEAMGFSASYNFTSDPDFKDIGVPKPLP 169

  Fly  1904 --HNELNGTEGTIESPHFPSKFQ----DPVPYSWRITVDKEYVVAISLLYLRDLD---------- 1952
              ..|:.|.||.|||.......:    :.|...|.|.....     |.:|||.||          
Zfish   170 FCEFEMGGPEGIIESQQITKDGRALQTEAVDCKWYIRAPPR-----SKIYLRFLDYEMQNSNECK 229

  Fly  1953 QPHLNFYDGYSDI----GARIEVTDPDETIISSTNVVYFTSNRGP----FKLNWNRLSKEALRSN 2009
            :.::..|||.|.:    .........|..::|:..|:...::.|.    |::.:....:....::
Zfish   230 RNYVAVYDGSSSVEDLRNKFCSTVANDVMLVSALGVIRMWADEGSRKSRFRILFTTFQEPPCEAD 294

  Fly  2010 RTAEERTRQCGNQLITIDRSVIGFHSPGYP---------------------NGYEQDLNCFWTLV 2053
             |....:..|.|..:..:    |..:..||                     ||....:.|...|:
Zfish   295 -TFFCHSNMCINNTLVCN----GIQNCVYPWDENHCKEKRKANILDSLNNTNGTIIGVTCCIVLI 354

  Fly  2054 ---------PSNPAMHAVLTLSQIDLEIFSEDCIADYVKIFSGSDLQNWSELRTLCSLPTESSDR 2109
                     ...|....:|.....|..:|.|        :|....   ..||.||.|....|:|.
Zfish   355 LLIVSVIVQIKQPRKKYILRREDFDPTMFQE--------VFQEPP---HYELCTLRSAAATSADL 408

  Fly  2110 VFHGRPYLRVEFVTDPSVNKTGFNGIVRTACG-SEITASKGLVNITEILKVLPRPNHDCVWTIKV 2173
            .     .|..:|.:...:.:.....|....|| |:|:::||           .|.|      :..
Zfish   409 A-----ELAEDFESYHKLRRASSRCIHEHHCGSSQISSNKG-----------SRTN------LSA 451

  Fly  2174 RQGRRIKI--DFPDFQL-----QNNMASGSSDCRNYLLLRNGNDEDSPFLGRGKYCE--DVVHEV 2229
            |......|  |.|...:     |.|.       ||.|::|:...:|:.     ..||  |.:.||
Zfish   452 RDAAAAAILTDLPPQPMRPLPPQTNR-------RNILVMRHTYSQDAT-----DACELDDELEEV 504

  Fly  2230 LNTSSNKAYIKFHFASPPRFL-----------VSFRFEEL--RYT 2261
            ..||..   :..|..:..|.|           .|.::|.:  |||
Zfish   505 PTTSHR---LSRHEKAVQRLLENSAILDQYERASMKYENVDRRYT 546

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CubnNP_727348.2 EGF_CA 156..190 CDD:238011
EGF_CA 192..233 CDD:238011
EGF_CA 282..322 CDD:214542
EGF_3 328..366 CDD:289699
EGF 430..457 CDD:278437
EGF_CA 469..503 CDD:238011
CUB 509..622 CDD:238001
CUB 627..737 CDD:238001
CUB 744..849 CDD:294042
CUB 853..970 CDD:238001
CUB 978..1094 CDD:238001
CUB 1100..1211 CDD:238001
CUB 1216..1330 CDD:238001
CUB 1446..1549 CDD:238001
CUB 1554..1667 CDD:238001
CUB 1792..1899 CDD:238001 41/110 (37%)
CUB 1910..1998 CDD:294042 23/109 (21%)
CUB 2019..2133 CDD:238001 24/143 (17%)
CUB 2140..2242 CDD:238001 26/111 (23%)
CUB 2263..2379 CDD:238001
CUB 2385..2511 CDD:238001
CUB 2516..2630 CDD:238001
CUB <2833..2892 CDD:294042
CUB 2898..3008 CDD:238001
CUB 3011..3127 CDD:238001
CUB 3130..3241 CDD:238001
CUB 3254..3363 CDD:238001
CUB 3379..3508 CDD:238001
CUB 3531..3601 CDD:294042
CUB 3623..3733 CDD:238001
neto1lXP_021325973.1 CUB 40..153 CDD:238001 43/112 (38%)
CUB <199..285 CDD:238001 18/90 (20%)
LDLa 291..325 CDD:238060 6/38 (16%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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