DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cubn and cubn

DIOPT Version :9

Sequence 1:	NP_727348.2	Gene:	Cubn / 326235	FlyBaseID:	FBgn0052702	Length:	3750	Species:	Drosophila melanogaster
Sequence 2:	XP_021326049.1	Gene:	cubn / 100144772	ZFINID:	ZDB-GENE-060228-6	Length:	3626	Species:	Danio rerio

Alignment Length:	3909	Identity:	1192/3909 - (30%)
Similarity:	1788/3909 - (45%)	Gaps:	563/3909 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 PKIISKDGNLIFESGANRNISFRLSGNSRLTINEELDVMELLLATSGSKK--------RSGGKDD 89
            |::||::|:|.|.:|.|::|.|..||...|.:..|    :|:|..:..||        ::.|..:
Zfish    41 PRMISENGHLTFSAGYNKDIRFTTSGTGSLKVGAE----DLILQINQIKKNKEDIDTIKNSGPSE 101

  Fly    90 DFVDARELADQLADFNRRAFGANGLSAMLRVQQNRTRGSMALLRRFQTRLRALENRVDRMKTDLE 154
            |..:...|.|                                     ||:..||::|..::..::
Zfish   102 DIKNQLHLLD-------------------------------------TRVTTLESKVQSIEQTVQ 129

  Fly   155 ANSCASGPCENGGTCYNTYTGFRCQCRSAFEGTKCEMDVNECALYEGTDLGCQNGGQCQNHFGTY 219
            ..:|:|.||:|.|||.|....|.|.|...::|..|.:|||||.:..||.||||||..|.|..|:|
Zfish   130 RKTCSSNPCQNTGTCLNLLDAFHCLCPDNWQGPTCAVDVNECQVLAGTPLGCQNGATCNNTPGSY 194

  Fly   220 SCLCQPGWHGMHCTQRKADCSQSSAWELCGHGSCVPS----ADDAGYRCICEPGWKTNGLTPICG 280
            :|.|.|.|:|.|||.|..||:..|. :||.||.|:.|    .::..|:|||:.||.:......|.
Zfish   195 TCTCTPEWYGPHCTSRYDDCAGGSQ-DLCVHGLCIDSDRVNPNEPKYKCICDAGWTSPPGVAACT 258

  Fly   281 EDVDECSDSAAHKPCSTS----CINLPGSFTCAPCPAGLTGNGVSCRDLDECQTNNGGCSLSPKV 341
            .|:|||  |...|||||:    |.|..|||.|..||:|..|||.||:|:|||.|||||||.||.|
Zfish   259 ADIDEC--SLPTKPCSTNPPVECFNTLGSFYCGACPSGWQGNGYSCQDVDECATNNGGCSTSPFV 321

  Fly   342 DCINTYGSYHCGECPVGWTGDGRKCERSPQDIDIPAGQTPRTCPAGNNPCYPTASCFLISGTT-- 404
            .|:||.||:|||:||.|:.|||:.|.::    ||        |...|..|:|.|:|....|:|
Zfish   322 PCLNTMGSFHCGQCPPGYEGDGKTCTQA----DI--------CSTNNGGCFPLATCTSTPGSTIP 374

  Fly   405 SCRCPMGMVGTGYGPNGCVNGTTTNCKENPCLNGGICLFAGPSNYTCLCPIGFRPPICEPQPSPC 469
            .|.||.|.||.||||.||...:......|||:||.....|  :.|.|.|..|:....|:...:.|
Zfish   375 LCTCPPGYVGNGYGPTGCTQISDICGTSNPCVNGQCENTA--TGYVCHCDPGWAGQNCDQNMNEC 437

  Fly   470 DQHPCKNGGRCRPTTSGDLFVCQCLPGYRGRLCETRFSSCNGMLSAQSGRLRYPPE-GTG-YEHN 532
            ..:||:|||.|....:|  :.|.|...:.|..|:|....|.|:|.:.:|...||.. ||| |:|.
Zfish   438 SSNPCQNGGTCTDGING--YTCTCTAQWTGPQCQTPQQECGGILESPAGTFSYPNNPGTGDYDHQ 500

  Fly   533 AQCAWVIRTNESLVVNVTFNSFDVEDSTECRFDWLQINDGRSAAAQIIGRYCGNHLPHGGNIVSS 597
            ..|||||||:.:.::.:||..||:|:|..|.||:||::||.||:|.:||:|||:..|  ..:.||
Zfish   501 VSCAWVIRTDPNQILRITFPFFDIENSASCNFDFLQVHDGESASAFVIGKYCGSAAP--AELFSS 563

  Fly   598 GNQLYLWFRSDNSTAKEGFDLTWNSMEPQCGGRLNFETHGTLASPGSPGNYPKNRDCRWQLVAPT 662
            .|.||.|||||:|.:..||.:.|.|..|.|||:|. .|:|.:.|||.|||||.||||.|.:....
Zfish   564 HNSLYFWFRSDHSVSAGGFTVAWQSQAPVCGGQLT-NTYGDIKSPGYPGNYPPNRDCYWTVNVNP 627

  Fly   663 TKRIKLTFFSLQLEQHANCNFDYVLIKDSISGRE--LAKYCTTGAPAPLLLPTHLAEIHFHSDAE 725
            ...|...|.:|.||.|.|||||::.|:|.:...:  |.|||:|.:|.||......|.||||||..
Zfish   628 GLLITFAFGTLSLEHHDNCNFDFLEIRDGLLPEDSLLGKYCSTASPPPLQTTGPSAWIHFHSDFS 692

  Fly   726 GSDTGFQLHYSVEERVPGCGGVYTAKEGTISESSTANTEPGGVSCEYEIHLAVGEQVVIQFARLE 790
            .||.||.:.|:.....||||||:|..||.|...:..|.......|.|.|.:...|||.:.|..::
Zfish   693 ISDRGFHITYTTSPSDPGCGGVFTETEGIIISPNWPNNYAHNRQCIYIIRMPRSEQVALNFTHMD 757

  Fly   791 LD-----PLDCLEVLDITDEGGSILQEKICGSDASRLNPPTFTSEFNRLKIKF-----YARAGSF 845
            |:     ..|.:||.|.|.|...:: .|.||:..    |....|..|.|.|:|     .:||| |
Zfish   758 LEIHTGCLFDFVEVRDGTGETDPLI-GKYCGNTL----PAPILSTTNGLWIRFQSDSSVSRAG-F 816

  Fly   846 QLNYRMACDYKLNNEQGTITSPGYPNLTRSDRICTYTISTATNTVISLKRIDFQLTNGESDDDDN 910
            :..|.:||...|:. .|.|.:|.:|:....:::|.:.|:.....|::|..:.|       |.:.:
Zfish   817 RAMYELACGGTLSG-TGQIRTPFHPDPYPHNKVCEWVINQPEGYVVTLNFLTF-------DVEGS 873

  Fly   911 DECLTTNLRINDG--LNRKILGPYCGKNQPEENFVSETNYLQLHLSTDVDSMGRGFKFEYRALAT 973
            ..|...::.:.||  .:..::|.|||...| ....|....:.:...||......||..|:.:...
Zfish   874 STCAFDHVEVRDGPSSSSPLIGRYCGVEMP-PMLESTQKSMFIQFKTDASVSNHGFTAEFGSAEQ 937

  Fly   974 GNDKCGGVHTRSGDHIRLPVHDDSYAGEATCYWVIMAPANKAIRLHWNSFSLENAVDCIYDYLEI 1038
            |   ||...|........|.|...|...|.|.|.|..|....|||.::.|::|...:|.|||:::
Zfish   938 G---CGETLTEPTGSFTSPGHPTEYPHGANCTWYISVPPGHLIRLSFSYFNMEFHTNCAYDYVDV 999

  Fly  1039 YDSLGAQVNDERSKPLAKYCGNSVPEDLLSHSRQLVLKFVSDYSESDGGFDLTY-TFEDRAKCGG 1102
            ||: |..:.   ...|.::||.|||..|.|....:.:..|||.|.|..||...| :......|..
Zfish  1000 YDN-GTALT---GTLLGRFCGRSVPPSLTSTDSLMTVLLVSDSSLSAEGFSADYISINATTDCSK 1060

  Fly  1103 HIHASSGELTSPEYPANYSAGLDCDWHLTGTIDHLLEIQVENFELEQSPNCSADYLEVRNGGGTD 1167
            ....|:|||:||.||.||....:|.:.:...::..:.:...:|:||...:|..||||:|:||...
Zfish  1061 VFRTSTGELSSPNYPDNYPTNRECVYRIIVEVNMQIMLNFTDFQLEGFSSCGFDYLEIRDGGYET 1125

  Fly  1168 SPLIGRFCGRDIPARIPGFSHEMRLILHTDSAINGRGFRLRWRIFAFGCGGSLRSNMGAISSPRY 1232
            |||||::||.:.|..|...|:.:.:...:|.::..|||:..|.....||||:|.::.|..:||.|
Zfish  1126 SPLIGQYCGTNAPPIIVSHSNRLWMKFRSDHSLTYRGFQAHWDGTQTGCGGTLTTSSGGFTSPNY 1190

  Fly  1233 PNSYPNMAHCEWRISLHPGSGISLLIEDLELEGLSNCYYDSVKIYTGIKLPNQSPCKVLCK--DD 1295
            |..||..|.|.|.|....||.|.|...|..||...:||:|.:.:|.|    |.|....|.|  .:
Zfish  1191 PLPYPANAECYWHIKTSAGSRIQLSFGDFHLEDTVDCYFDYLMVYDG----NNSNAHQLAKLCGN 1251

  Fly  1296 DLHNPLIQLENNKGTIVFDSDASNTFRGFRISYKANCIRNLTA--TTGTIESLNYMEPFWETIP- 1357
            .:..|:.....|. .:...:|:.....||..:|.:.|...|.|  :.|.||||||...:    |
Zfish  1252 QIPAPISSSRENM-YVKLRTDSIIHTGGFLANYHSTCNGMLIANRSRGMIESLNYPNDY----PS 1311

  Fly  1358 -INCSWTIRAPKGNRV-------LVEVSHLARHEQHVPTATMPGGLYIVDGRNVQE--------I 1406
             .:|||||:|..||.:       .||.|....:: ||.       ||  ||.|.|.        .
Zfish  1312 HADCSWTIQAYMGNTINYTFIAFEVEQSDGCGYD-HVK-------LY--DGPNDQANLIGTFCGN 1366

  Fly  1407 VTPQAMNISGEVLTVVHNA----SNVNFQLDYRIDGCMEELRGTFGFFQSPNYPKMYPNNLECYW 1467
            |.|.|...||..|.:|..:    |...||:|:..:||..||.|..|.|.||.||..||.|.||.|
Zfish  1367 VPPPAGTTSGTSLHIVFRSDMSISYRGFQMDWYQNGCGGELFGPVGTFNSPGYPGQYPMNRECVW 1431

  Fly  1468 LITVEQDSAIELTINNIDLEDSPNCTKDALTVSNHKN-SVEVHERHCGSTTK-----LVITSSGH 1526
            .|.....|:|.:||...|:|..|:|..|.|.|....: |.....:.|  ||:     |.::|:|:
Zfish  1432 HIHTSPGSSISITILEFDVEYHPDCNYDKLEVYGGPDLSAPRLAQLC--TTRPPSNPLQVSSTGN 1494

  Fly  1527 RLHVRFISDNSHNGLGFEATYRTVKATCGGKLTARNGVIESPNYPLNYPAHSRCEWQVEVSQHHQ 1591
            .:.|||.||...:|.||.||:..|...|||.:||.:|.|.||.||.|||.::.|.|.:.|...|:
Zfish  1495 AVTVRFTSDAVVSGRGFNATWVEVPGGCGGSVTAPSGEIHSPQYPSNYPDNADCSWVITVDAGHR 1559

  Fly  1592 IVFEMADLNLESGYDCNWDYLEAYDLTEDDTEGERLFKVCGDETEDDKLLSSSSNMAVVRFISDD 1656
            :.|...||::|:.:.|::||:..:|...:  ....|.:|||  |.....::||:|:..|.|.||.
Zfish  1560 VFFNFTDLDIENQFSCSYDYVAIHDGPHE--HSPLLAQVCG--TSRPPPVTSSTNVIYVCFRSDH 1620

  Fly  1657 SVSKKGFRLHFHESCGQTIIVDET-------MFDYIQMSRQAARNESCLWVFQAVEPNKRIIFTP 1714
            |::.:||...|.|:||..|:.|:.       .:.|     ....|:.|.|:.:|.||...:..:.
Zfish  1621 SLNHRGFSAQFSEACGSFIVTDDVGGEIASPRYPY-----PYPPNQDCSWIIRAQEPFNHVTLSF 1680

  Fly  1715 THVKLREDANQQYPTEGDCLNVGVKIYEGTEPQGTPRLKFCRS---HPPALISNGQALTVSVPLQ 1776
            |..:| |..|      .:|.:..|:|.:|...|.....::|.|   ||...:||      ::.::
Zfish  1681 TDFEL-EMLN------SNCTHDSVEILDGDNVQAPSVGRYCGSNLPHPVTSLSN------AMVVK 1732

  Fly  1777 LVEE-------FQGHYMTMDTSCGSIYNALSGKFTSPYYPASYPPNIECLWLLEASMGNSLSLTL 1834
            .|.:       |:..||...:.||.:.|..||.|.||.||..||||:||:|.|.:|.||.:.|:.
Zfish  1733 FVSDHAVGRKGFRATYMASTSGCGGLLNMESGAFNSPNYPDVYPPNVECVWTLTSSPGNRIQLSF 1797

  Fly  1835 ESMDLEKSESCNRDYLEVREESESGQLIGVYCGNEVP-------GVIHSRGAIWMKFKSDDDNVG 1892
            ....|:.|..|:.||||:||...:|.|:|.:||:.:|       |.|     :|:||.||....|
Zfish  1798 IMFQLQPSSDCSNDYLEIREGHSTGALVGRFCGDSLPTNYTSITGHI-----LWIKFISDSSISG 1857

  Fly  1893 EGFMASYNYEHHNELNGTEGTIESPHFPSKFQDPVPYSWRITVDKEYVVAISLLYLRDLD----- 1952
            .||.|.:::.:.|::.|:.|.|.||.:|..:.:...|.|.:|||.:..:.|..|   |:|
Zfish  1858 AGFRAVFSHLYGNDITGSTGLIASPLYPRTYPNNADYRWTVTVDSDSHIQIQFL---DIDIEDLF 1919

  Fly  1953 ---QPHLNFYDGYSD----IGARIEVTDPDETIISSTNV-VYFTSN-----RGPFKLNWNRLSKE 2004
               ...|..|||.|.    :|....:|.|:....|.:.: :.|.|:     :| |.:.|..:.
Zfish  1920 NCLYDKLKIYDGPSTNSFLLGEFCGLTLPNPVRSSGSAITLEFQSDTVIGGKG-FLIEWTAVQ-- 1981

  Fly  2005 ALRSNRTAEERTRQCGNQLITIDRSVIGFHSPGYPNGYEQDLNCFWTLVPSNPAMHAVLTLSQID 2069
              .|..........||..|:|.|.....| |||:|..|:.:|:|.|.:  .:|:......|..:|
Zfish  1982 --GSGPLPTIEPGACGGTLVTGDTPQFLF-SPGWPELYQHNLDCSWVI--RSPSSIVEFNLLSLD 2041

  Fly  2070 LEIFSEDCIADYVKIFSGSDLQNWSEL-RTLCSLPTESSDRVFHGR-PYLRVEFVTDPSVNKTGF 2132
            :| ....|:.|.:.|..|.  .|.|.| ..:|......|   .|.. ..:.:.|.:|.|:|..||
Zfish  2042 ME-DEVSCLHDSLDIRDGE--TNASPLIAKVCGRQLPGS---LHSTGDAMLLRFTSDGSINGRGF 2100

  Fly  2133 NGIVRTACGSEITASKGLVNITEILKVLP---RPNHDCVWTIKVRQGRRIKIDFPD-FQLQ---N 2190
            |......||..:...:|:::..:    .|   :||.:|.|.:.|..|.|:.:.|.. ||:|   |
Zfish  2101 NATFSRGCGGFLHTDRGVLSSPQ----YPQNYKPNLNCNWQVMVTPGFRVSVTFQSPFQVQGYGN 2161

  Fly  2191 NMASGSSDCRNYLLLRNGNDEDSPFLGRGKYCEDVVHEVLNTSSNKAYIKFHFASPP-------R 2248
            ..::|     :||.||||.|.:||.|. |:.|...|.....|:.|..|.  ||.|..       :
Zfish  2162 QCSTG-----DYLELRNGPDGNSPTLS-GRLCGSNVPSTFQTTDNSLYA--HFVSDGSNEGNGFK 2218

  Fly  2249 FLVSFRFEELRYTDSGRIRLSASGDEQFISSPYYPHLPHPHSECIWIVEAPPEHRIMLHFQGAFD 2313
            .|    ||.......|.|.|:......:|:||.||.....:.:|:||:..|....:.|.|:|.|.
Zfish  2219 LL----FEAHSSACGGLIELNDGDPPGYITSPDYPSNYPQNIDCVWIITVPNGEAVQLDFEGDFY 2279

  Fly  2314 MLDATGEPEE-CQREFVLINDGSTELRPEIGRYCGNRKPDTIYSTGNQMRIRYFTDVSEPHMGFN 2377
            :     ||.. |..:::.|.||.|.....|||.|||.:|.|.:|:|..|.:|:.||.|..|:||.
Zfish  2280 I-----EPHSGCLFDYIEIRDGPTSDADLIGRLCGNTRPSTQHSSGTTMYLRFRTDASVTHIGFK 2339

  Fly  2378 ASLSVARCGGSFHSPEGVIASPSRDLLLIHEEGKQLQE---CVYTIELEKGSTIDLTSEYLQIPT 2439
            |..|:|.|||::....|||.||.       ..|....:   |.:.:|...|..:.||  |.....
Zfish  2340 AKYSIAVCGGTYIGQNGVIRSPG-------FPGSNYPDNSNCEWYLEGPTGHYLTLT--YTAFDL 2395

  Fly  2440 LRNGSCSQRNHLMLEEMDAFG-LDGEEKIVDTLMLCGMEAKHLISETNKIVFRYRFLDGIPAENQ 2503
            ..:.:|:. :::.:.|.:|.| |.|:.        ||......:...:...: .:|:....|...
Zfish  2396 QSSANCNS-DYVEIREYNASGRLLGKH--------CGNNLPAPMDTGDSFAY-VKFVSDASANAG 2450

  Fly  2504 GFRLKYTSLGSRCGETIYASVGVLQTPGYPLGVPHPMHCKWQVQVPKGRRVRLEILDFNTGTNMD 2568
            ||.|.:.:....||..:.|..|.:.:|.||...||...|:|.:.||:||||.|.|.|
Zfish  2451 GFSLSFEASIEECGGDLNAPFGTISSPNYPNLYPHSRICRWSITVPQGRRVTLTIND-------- 2507

  Fly  2569 LRGRLGFRGRLTVANDF------------KMQSILGRYNVDPPAEVLSSDNTMGIDAFLLPIVQN 2621
                |....:.|.|.||            ::..:.|  .|....:|.||.|||.:.......|.|
Zfish  2508 ----LRLEDQSTCAFDFVEILNGLTPSAPRLDRLCG--TVPAGTQVKSSGNTMTVIFSTDSSVSN 2566

  Fly  2622 HGIKLRFSAYGSSSCPGFTVMMNEVADI---QFQRFNISRPLHCSYKVVPP--SNSTLLIRVKEY 2681
            .|....:|:..|:.|.|   ::||..:.   .|...|.|..|:|.:.:..|  :||::::.:.|.
Zfish  2567 GGFTADYSSEESAVCGG---ILNEPGNFTSPDFGNGNYSNNLNCEWLIQNPHHTNSSIVVIIDEL 2628

  Fly  2682 NTTSVMMWNTHMCALLSPLKFNRLEQEEELMERILCDYQSPAPGKPL----PSIRLPFPIQLVVS 2742
            :.      ..|.......|:|...:...||:.| ||. |:| |..|:    ||:.:.|.....|.
Zfish  2629 HL------EHHQTCEWDYLEFRLGDHNGELLTR-LCG-QTP-PSIPIVVSTPSLWVHFLSDEAVG 2684

  Fly  2743 ASARNAMTNLVLSYSTQSCGGVIILEPGDNMTVHQPSGMVSAAGAID-------CAWAIGPYTDA 2800
            .....|      :|....|||.   :.||       .|::|:.|..:       |.|.:
Zfish  2685 DLGFKA------TYYFSECGGT---QSGD-------GGVISSPGYPNVYPSPSRCTWLL------ 2727

  Fly  2801 SGEDEVLVPQDIQLEVSVYNVNLPAPSPSAQSPEAPCLHHYLKVYNGPDQNSPSLGLFCN----- 2860
                |..|...:.|..:.:.|          ...:.|:...:.::||....||.:|.:|.
Zfish  2728 ----EAPVGHTVVLTFTYFEV----------EEHSQCVWDSVTIFNGASSGSPIIGQYCGHNSPG 2778

  Fly  2861 --QATAVNMVVERGLFLEYHSDS---FSANATFNVSIKYGSGCGGKLVY----PYRAIDFAEQYK 2916
              ::.:..:||   :||..|:.|   |:  ||::..   .:|||| :::    ..::.::.:.:.
Zfish  2779 TIRSGSNKLVV---VFLADHTVSKGGFA--ATWSTD---STGCGG-IIHADTGTIKSPNYPQNFP 2834

  Fly  2917 NNVECIWEVEATMGYHIGLTFQGRFYIEDSPG-CTKDYLLVQQRNETTGNWTD--------LQRI 2972
            .|:||.|.:.|..|.|:.:.|...|.|.||.| |...|:.:         |:|        |...
Zfish  2835 TNIECSWTIIAHDGNHLEMGFASDFQIPDSSGQCQNSYIKM---------WSDNIQNDENLLATG 2890

  Fly  2973 CGRVAPEMINTTSPYLRLIFRSDGDVVADGFLAKFERNCGGLLYADSTEQELASPGFPNGYEKYL 3037
            ||..||..|......:...|:| .|....||.|.|...||....|.|  ..:.||.:|:.|....
Zfish  2891 CGTTAPAAIIAPRNVITARFQS-SDTPGKGFSAAFYTTCGANFTASS--GRVVSPNYPDHYPANS 2952

  Fly  3038 QCNWTIVPRSPSMGGVLVSFVNFDLEQGPISVCLYDNLTVTTKDKGKDPQQTTLCG--VKHNHEY 3100
            .||:.|  .:.....|:::|..|.:|..  |.|:||.:.:.:..........||||  :......
Zfish  2953 NCNYII--NAGEQFVVVLTFRTFQIEAH--STCVYDGVKIYSGTTASSSPLATLCGNTIPGIFTT 3013

  Fly  3101 RGKEYVNLLLRTDGSYSGRGFTLLYTSRLCGGIISRTSMVESPVQHTDNTLPPGSDCYWNLTAPA 3165
            .|...:|..  :|......||...||:..|||:.:.|:.......|:.:......:|.:::....
Zfish  3014 FGPMLINFY--SDSIIHDNGFLAEYTTIPCGGVFNGTAGTIGSPSHSISNYHHNINCTYHIYVRN 3076

  Fly  3166 GYKFNIKFLFIDFEANSNCAYDGVEVFSG-----PIPDERYRWGRFCGRINEDLPLISIPQERGI 3225
            ....|:||...:.||:|.|.:|.|.|:.|     |:      .|:|||   .:||    |..|..
Zfish  3077 NRVINLKFNSFNLEASSTCNFDYVAVYDGESTLAPL------MGKFCG---HELP----PNLRSS 3128

  Fly  3226 I-HSF----SDDRDPSRGFRA----LVRVMPNCDEKISLNGSSRYVYSKFNNAGGYQNDLDCQIV 3281
            . |.|    :|....:.|:||    .:.....|...:| :.|..:.....:..|.|:..:||...
Zfish  3129 TNHMFLQFVTDSSVAAEGWRATYSETLGPQQGCGGFLS-SPSGMFGSPDIDMNGQYEPHMDCMWT 3192

  Fly  3282 FRVNPDQQISVEFSNFHVQDTDG--CRSDYVELRDGGGTFADIIGRFCGQNQPPTLRTTRHTLYM 3344
            ..|..::.|::.|.:|.::.:.|  ||.|:|.:.||......::|.|||...|....:..:.|.:
Zfish  3193 IAVEVNKAINLTFISFELEGSTGTLCRYDHVTIYDGDSANFPLVGTFCGDVIPAPFISASNFLTV 3257

  Fly  3345 RFVTDNKVTDTGFQVTINAIPRLCGSSEITLSADGTKEVTINSPARTPGGNYPNG----VSCFWK 3405
            .|::|..|:..||..|.:.:..|||.:   .:|..|.: ||.||.      |||.    .||.|.
Zfish  3258 HFISDGTVSRRGFNATYSTVNSLCGGA---FNATATSQ-TITSPL------YPNAYPPFTSCRWV 3312

  Fly  3406 IKGDSL--LRVQFVNFDLHGPNQNGSCVDDYLKIYNSEDAPLLEQGLGTDLVFNGQTSSKNGFGF 3468
            :...|.  ::|....|.|   :.:.||..::|:.   :|.|:            |.....:.|..
Zfish  3313 LDAPSQEGVKVSVQQFHL---DTSQSCTSNFLEF---KDFPV------------GDYGQAHKFCS 3359

  Fly  3469 ATEHVYCGNVKPDIY-YGRSSEVYLKFRSKGLEQHGGFQL--QVALNSN-RERHYDGLQ--GRVH 3527
            |..||      ||.| |||:  :::.|:|:......||.|  |||..|. .|:.|..|:  |...
Zfish  3360 ADSHV------PDFYSYGRT--MHITFKSEAFMTGNGFSLSYQVAGCSRVYEQEYGYLKSPGWPD 3416

  Fly  3528 L-SQSADCNIIIRAPPNYTLSLYYTELIFGTY-DCEMENLEVFD---RTNRSLQRVCSFVDMGKS 3587
            | ..:.:|:|:::||.|..:||::|.....|: .|..:.|||.:   .|:..|.:.|     |.:
Zfish  3417 LYPHNLECSIVLQAPQNSFISLFFTSFDVETHPSCNFDYLEVRNGSTATSPLLGKHC-----GNT 3476

  Fly  3588 L----FSNANELRLQMKTGSYLT--SLDLTYLASPVEKGPGCGGQFYNTEGIFSNPFYPNNVRNN 3646
            |    |..:|||.:..|:....|  ..::|:.:||    .||||..|...|.|::|.||....|.
Zfish  3477 LPNPVFPGSNELFIFFKSDFTTTRNGFEITWTSSP----QGCGGVLYGDHGSFTSPNYPGTYANG 3537

  Fly  3647 SECQWIVRVPSNNVVFLTFEVFNLGSKTTCHTDYLQILE-QDATGEEREMRRFCG-EDNPKYYKS 3709
            |.|:|.:|.||..||.:||...::.....|..:||::.: .||...  .:..:|| |.|...:::
Zfish  3538 SSCEWSIRAPSGRVVTVTFNQISIDDPGDCQNNYLKLFDGPDANSP--AVGPYCGLETNIAPFRA 3600

  Fly  3710 RRSQVLVRF 3718
            ..:.|.|:|
Zfish  3601 SSNLVFVKF 3609

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cubn	NP_727348.2	EGF_CA	156..190	CDD:238011	13/33 (39%)
		EGF_CA	192..233	CDD:238011	23/40 (58%)
		EGF_CA	282..322	CDD:214542	22/43 (51%)
		EGF_3	328..366	CDD:289699	25/37 (68%)
		EGF	430..457	CDD:278437	9/26 (35%)
		EGF_CA	469..503	CDD:238011	11/33 (33%)
		CUB	509..622	CDD:238001	54/114 (47%)
		CUB	627..737	CDD:238001	52/111 (47%)
		CUB	744..849	CDD:294042	36/114 (32%)
		CUB	853..970	CDD:238001	26/118 (22%)
		CUB	978..1094	CDD:238001	39/116 (34%)
		CUB	1100..1211	CDD:238001	38/110 (35%)
		CUB	1216..1330	CDD:238001	37/115 (32%)
		CUB	1446..1549	CDD:238001	41/108 (38%)
		CUB	1554..1667	CDD:238001	41/112 (37%)
		CUB	1792..1899	CDD:238001	48/113 (42%)
		CUB	1910..1998	CDD:294042	27/105 (26%)
		CUB	2019..2133	CDD:238001	33/115 (29%)
		CUB	2140..2242	CDD:238001	33/108 (31%)
		CUB	2263..2379	CDD:238001	41/116 (35%)
		CUB	2385..2511	CDD:238001	28/129 (22%)
		CUB	2516..2630	CDD:238001	36/125 (29%)
		CUB	<2833..2892	CDD:294042	16/68 (24%)
		CUB	2898..3008	CDD:238001	32/122 (26%)
		CUB	3011..3127	CDD:238001	29/117 (25%)
		CUB	3130..3241	CDD:238001	30/120 (25%)
		CUB	3254..3363	CDD:238001	29/110 (26%)
		CUB	3379..3508	CDD:238001	36/137 (26%)
		CUB	3531..3601	CDD:294042	22/77 (29%)
		CUB	3623..3733	CDD:238001	32/98 (33%)
cubn	XP_021326049.1	EGF_CA	133..164	CDD:238011	13/30 (43%)
		EGF_CA	167..208	CDD:238011	23/40 (58%)
		EGF_CA	260..299	CDD:311536	20/40 (50%)
		EGF_3	308..346	CDD:315598	25/37 (68%)
		EGF_3	352..387	CDD:315598	14/34 (41%)
		EGF_CA	397..430	CDD:238011	10/34 (29%)
		EGF_CA	433..469	CDD:238011	11/37 (30%)
		CUB	475..588	CDD:238001	54/114 (47%)
		CUB	593..704	CDD:238001	52/111 (47%)
		CUB	711..820	CDD:278839	36/114 (32%)
		CUB	824..932	CDD:238001	25/116 (22%)
		CUB	939..1049	CDD:278839	38/113 (34%)
		CUB	1058..1166	CDD:278839	37/107 (35%)
		CUB	1174..1285	CDD:238001	37/115 (32%)
		CUB	1287..1399	CDD:238001	41/125 (33%)
		CUB	1403..1515	CDD:238001	44/113 (39%)
		CUB	1522..1632	CDD:238001	41/113 (36%)
		CUB	1635..1750	CDD:238001	29/132 (22%)
		CUB	1755..1865	CDD:238001	48/114 (42%)
		CUB	1869..1979	CDD:238001	30/113 (27%)
		CUB	1994..2105	CDD:238001	35/119 (29%)
		CUB	2108..2223	CDD:238001	38/130 (29%)
		CUB	2228..2344	CDD:238001	42/120 (35%)
		CUB	2347..2458	CDD:238001	28/129 (22%)
		CUB	2463..2575	CDD:238001	36/125 (29%)
		CUB	2581..2694	CDD:238001	31/130 (24%)
		CUB	2697..2808	CDD:238001	30/145 (21%)
		CUB	2813..2926	CDD:238001	33/123 (27%)
		CUB	2928..3038	CDD:238001	29/117 (25%)
		CUB	3041..3152	CDD:238001	32/123 (26%)
		CUB	3161..3274	CDD:278839	29/113 (26%)
		CUB	3281..3395	CDD:238001	39/149 (26%)
		CUB	3399..3509	CDD:238001	31/114 (27%)
		CUB	3514..3626	CDD:238001	32/98 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	114	1.000	Domainoid score	I6050
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37434
Inparanoid	1	1.050	1565	1.000	Inparanoid score	I85
OMA	1	1.010	-	-		QHG46457
OrthoDB	1	1.010	-	-		D3206at33208
OrthoFinder	1	1.000	-	-		FOG0006182
OrthoInspector	1	1.000	-	-		oto41476
orthoMCL	1	0.900	-	-		OOG6_106358
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4462
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.880