Protein Alignment Arp2 and ACTL6A

DIOPT Version :9

• Sequence 1: NP_001259621.1
• Gene: Arp2 / 32623
• FlyBaseID: FBgn0011742
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: NP_004292.1
• Gene: ACTL6A / 86
• HGNCID: 24124
• Length: 429
• Species: Homo sapiens
• Alignment Length: 455
• Identity: 129/455 - (28%)
• Similarity: 202/455 - (44%)
• Gaps: 112/455 - (24%)

  Fly     9 IVCDNGTGFVKCGYAGSNFPTHIFPSMVGRPMIRAVNKIGDIEVKD----LHVDDLMVGDEASQ- 68
            :|.|.|:..|:.||||.:.|...||:.:|  |:        :|..|    :.:|    ||:..|
Human    14 LVFDIGSYTVRAGYAGEDCPKVDFPTAIG--MV--------VERDDGSTLMEID----GDKGKQG 64

  Fly    69 -------------LRSLLEVSYPMENGVVRNWDDMCHVWDYTFGPKKMDI--DPTNTKILLTEPP 118
                         .|..:|...|::||:|.:||....:.|:|:   ||.:  :.:...:|::|.|
Human    65 GPTYYIDTNALRVPRENMEAISPLKNGMVEDWDSFQAILDHTY---KMHVKSEASLHPVLMSEAP 126

  Fly   119 MNPTKNREKMIEVMFEKYGFDSAYIAIQAVLTLYAQGLISGVVIDSGDGVTHICPVYEEFALPHL 183
            .|....|||:.|:|||.|...:.::...||||.:|.|..:|:::|||...|...||::.:.|...
Human   127 WNTRAKREKLTELMFEHYNIPAFFLCKTAVLTAFANGRSTGLILDSGATHTTAIPVHDGYVLQQG 191

  Fly   184 TRRLDIAGRDITRYLIKLL------LLRGYAFNHSADFETVR-------IMKEKL---------- 225
            ..:..:||..||....:|.      |:..|..   |..|.||       ..||||
Human   192 IVKSPLAGDFITMQCRELFQEMNIELVPPYMI---ASKEAVREGSPANWKRKEKLPQVTRSWHNY 253

  Fly   226 ---CYI-------------GYDIEMEQRLALETTVLVESYTLPDGRVIKVGGERFEAPEALFQPH 274
               |.|             .||   ||..|...||   .|..|:|.....|.||.:.||.||.|.
Human   254 MCNCVIQDFQASVLQVSDSTYD---EQVAAQMPTV---HYEFPNGYNCDFGAERLKIPEGLFDPS 312

  Fly   275 LINVEG------PGIAELAFNTIQAADIDIRPELYKHIVLSGGSTMYPGLPSRLEREIKQ----- 328
              ||:|      .|::.:...::...||||||.||..::::||:|:......||.||:.|
Human   313 --NVKGLSGNTMLGVSHVVTTSVGMCDIDIRPGLYGSVIVAGGNTLIQSFTDRLNRELSQKTPPS 375

  Fly   329 LYLERVLKNDTEKLAKFKIRIEDPPRRKDMVFIGGAVLAEVTKDRDGFWMSKQEYQEQGLKVLQK 393
            :.|:.:..|.|.:             |:...:|||::||.:...:. .|:|||||:|.|.:.:::
Human   376 MRLKLIANNTTVE-------------RRFSSWIGGSILASLGTFQQ-MWISKQEYEEGGKQCVER 426

  Fly   394  393
            Human   427  426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp2	NP_001259621.1	ACTIN	6..393	CDD:214592	129/453 (28%)
ACTL6A	NP_004292.1	Actin	11..429	CDD:394979	129/455 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910