Protein Alignment Arp2 and ACTRT3

DIOPT Version :9

• Sequence 1: NP_001259621.1
• Gene: Arp2 / 32623
• FlyBaseID: FBgn0011742
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: NP_115876.3
• Gene: ACTRT3 / 84517
• HGNCID: 24022
• Length: 372
• Species: Homo sapiens
• Alignment Length: 389
• Identity: 138/389 - (35%)
• Similarity: 231/389 - (59%)
• Gaps: 31/389 - (7%)

  Fly     9 IVCDNGTGFVKCGYAGSNFPTHIFPSMVGRPMIRAVNKIGDIEVKDLHVDDLMVGDEASQLRSLL 73
            :|.|||:|.:|.|.||...|..|:|:::||...::....|.:|        |.|||:|...||.|
Human     8 VVIDNGSGMIKAGVAGCREPQFIYPNIIGRAKGQSRAAQGGLE--------LCVGDQAQDWRSSL 64

  Fly    74 EVSYPMENGVVRNWDDM----CHVWDYTFGPKKMDIDPTNTKILLTEPPMNPTKNREKMIEVMFE 134
            .:|||:|.|::.:|:||    .|::||     .:.:.|.:..:|:|||.:||..||:::.|:.||
Human    65 FISYPVERGLITSWEDMEIMWKHIYDY-----NLKLKPCDGPVLITEPALNPLANRQQITEMFFE 124

  Fly   135 KYGFDSAYIAIQAVLTLYAQGLISGVVIDSGDGVTHICPVYEEFALPHLTRRLDIAGRDITRYLI 199
            ..|..:.|::|||||.|:|.|..:|:|::||.|||...|::|.:.|||..::||:||.|:|.||:
Human   125 HLGVPAFYMSIQAVLALFAAGFTTGLVLNSGAGVTQSVPIFEGYCLPHGVQQLDLAGLDLTNYLM 189

  Fly   200 KLLLLRGYAFNHSADFETVRIMKEKLCYIGYDIEMEQRLALETTVLVESYTLPDGRVIKVGGERF 264
            .|:...|.....::|.:.|..:||..||:.  :..|:.:|.:...|.:.|.||||:||::..:.|
Human   190 VLMKNHGIMLLSASDRKIVEDIKESFCYVA--MNYEEEMAKKPDCLEKVYQLPDGKVIQLHDQLF 252

  Fly   265 EAPEALFQPHLINVEGPGIAELAFNTIQAADIDIRPELYKHIVLSGGSTMYPGLPSRLEREIKQL 329
            ..|||||.|..:|:|.|||.::.|::|...|..:|...:.:|:|:||||.:|||..||.::|.::
Human   253 SCPEALFSPCHMNLEAPGIDKICFSSIMKCDTGLRNSFFSNIILAGGSTSFPGLDKRLVKDIAKV 317

  Fly   330 YLERVLKNDTEKLAKFKIRIEDPPRRKDMVFIGGAVLAEVTKDRDGFWMSKQEYQEQGLKVLQK 393
                       ..|...:::..||.||..|::||::||.::..:| .|::..|::|.|..::.:
Human   318 -----------APANTAVQVIAPPERKISVWMGGSILASLSAFQD-MWITAAEFKEVGPNIVHQ 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp2	NP_001259621.1	ACTIN	6..393	CDD:214592	138/387 (36%)
ACTRT3	NP_115876.3	ACTIN	7..372	CDD:214592	138/389 (35%)
		NBD_sugar-kinase_HSP70_actin	9..372	CDD:302596	138/388 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820