DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arp2 and ARP2

DIOPT Version :9

Sequence 1:	NP_001259621.1	Gene:	Arp2 / 32623	FlyBaseID:	FBgn0011742	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_189336.1	Gene:	ARP2 / 822317	AraportID:	AT3G27000	Length:	389	Species:	Arabidopsis thaliana

Alignment Length:	396	Identity:	239/396 - (60%)
Similarity:	314/396 - (79%)	Gaps:	8/396 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDSKGRNVIVCDNGTGFVKCGYAGSNFPTHIFPSMVGRPMIRAVNKIGDIEVKDLHVDDLMVGDE 65
            ||:|  ||:|||||||:||||:||.||||.:||.:||||::|....:.:.:||     |::||:.
plant     1 MDNK--NVVVCDNGTGYVKCGFAGENFPTSVFPCVVGRPLLRYEESLMEQQVK-----DIVVGET 58

  Fly    66 ASQLRSLLEVSYPMENGVVRNWDDMCHVWDYTFGPKKMDIDPTNTKILLTEPPMNPTKNREKMIE 130
            .|:||..|:::||:.||:|:|||||.||||:.| ..::.|:|::.|||||:||:||:||||||||
plant    59 CSELRHQLDINYPVHNGIVQNWDDMEHVWDHAF-YNELKINPSDCKILLTDPPLNPSKNREKMIE 122

  Fly   131 VMFEKYGFDSAYIAIQAVLTLYAQGLISGVVIDSGDGVTHICPVYEEFALPHLTRRLDIAGRDIT 195
            .|||||.|...:|.||||||||||||::|:||||||||||:.||.:.::.||||:|:::|||.||
plant   123 TMFEKYNFAGVFIQIQAVLTLYAQGLLTGLVIDSGDGVTHVVPVVDGYSFPHLTKRMNVAGRHIT 187

  Fly   196 RYLIKLLLLRGYAFNHSADFETVRIMKEKLCYIGYDIEMEQRLALETTVLVESYTLPDGRVIKVG 260
            .||:.||..||||.|.:|||||||.:|||||||.||.:.|.:|.||||:||::||||||||||||
plant   188 AYLVDLLSRRGYAMNKTADFETVREIKEKLCYISYDYKRESQLGLETTILVKNYTLPDGRVIKVG 252

  Fly   261 GERFEAPEALFQPHLINVEGPGIAELAFNTIQAADIDIRPELYKHIVLSGGSTMYPGLPSRLERE 325
            .|||:||||||.|.||:|||.|:|::.|..||..|||.|..||:|||||||||||||||||||:|
plant   253 TERFQAPEALFTPELIDVEGDGMADMVFRCIQEMDIDNRMMLYQHIVLSGGSTMYPGLPSRLEKE 317

  Fly   326 IKQLYLERVLKNDTEKLAKFKIRIEDPPRRKDMVFIGGAVLAEVTKDRDGFWMSKQEYQEQGLKV 390
            |:..||:.|||.:.:.|.|.::|||||||||.||::||||||.:.||...||:::::|.|:|:..
plant   318 IQDRYLDTVLKGNKDGLKKLRLRIEDPPRRKHMVYLGGAVLAGIMKDAPEFWINREDYMEEGINC 382

  Fly   391 LQKLQK 396
            |.|:.:
plant   383 LNKMSQ 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp2	NP_001259621.1	ACTIN	6..393	CDD:214592	235/386 (61%)
ARP2	NP_189336.1	ACTIN	4..387	CDD:214592	237/390 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	498	1.000	Domainoid score	I75
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4181
Inparanoid	1	1.050	502	1.000	Inparanoid score	I315
OMA	1	1.010	-	-		QHG54319
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	1	1.000	-	-		FOG0003456
OrthoInspector	1	1.000	-	-		oto4230
orthoMCL	1	0.900	-	-		OOG6_102757
Panther	1	1.100	-	-	LDO	PTHR11937
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2348
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.930