Protein Alignment Arp2 and ACTL8

DIOPT Version :9

• Sequence 1: NP_001259621.1
• Gene: Arp2 / 32623
• FlyBaseID: FBgn0011742
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: NP_110439.2
• Gene: ACTL8 / 81569
• HGNCID: 24018
• Length: 366
• Species: Homo sapiens
• Alignment Length: 403
• Identity: 118/403 - (29%)
• Similarity: 201/403 - (49%)
• Gaps: 67/403 - (16%)

  Fly     6 RNVIVCDNGTGFVKCGYAGSNFPTHIFPSMV---------GRPMIRAVNKIGDIEVKDLHVDDLM 61
            |.||: |:|:||:|.|.||.|.|..:||::|         |....|....:| |::  .|.|..
Human     4 RTVII-DHGSGFLKAGTAGWNEPQMVFPNIVNYLPCKENPGPSYARRRVSLG-IDI--CHPDTF- 63

  Fly    62 VGDEASQLRSLLEVSYPMENGVVRNWDDMCHVWDYTF--GPKKMDIDPTNTKILLTEPPMNPTKN 124
                          |||:|.|.:.||:.:.::|.:..  ..::.::.|    :::||.|:....:
Human    64 --------------SYPIERGRILNWEGVQYLWSFVLENHRREQEVPP----VIITETPLREPAD 110

  Fly   125 REKMIEVMFEKYGFDSAYIAIQAVLTLYAQGLISGVVIDSGDGVTHICPVYEEFALPHLTRRLDI 189
            |:||:|::||.....|..:|.|..::|||.||::|||:|||.|:|.:.|.::...||...:.|:.
Human   111 RKKMLEILFELLHVPSVLLADQLQMSLYASGLLTGVVVDSGYGLTRVQPFHQGRPLPASGKTLEF 175

  Fly   190 AGRDITRYLIKLLLLRGYAFNHSAD------FETVRIMKEKLCYI------GYDIEMEQRLALET 242
            ||:|::.||:|.|      |....|      .|||.:.:...||:      ..|....|:.||:.
Human   176 AGQDLSAYLLKSL------FKEDCDRRCLFQLETVAVTQMNKCYVPQNLGEALDFRERQQSALDE 234

  Fly   243 TVLVESYTLPDGRVIKVGGERFEAPEALFQPHLINVEGPGIAELAFNTIQAADIDIRPELYKHIV 307
            :   .:|.||||..:::...:..|||..|.|.:....||.|......::::.:|.:||.|..|::
Human   235 S---NTYQLPDGSRVELTPMQRVAPEMFFSPQVFEQPGPSIPRAIVESVESCEISLRPLLVSHVM 296

  Fly   308 LSGGSTMYPGLPSRLEREIKQLYLERVLKNDTEKLAKFKIRIEDPPRRKDMVFIGGAVLAEVTKD 372
            ..||:|:|||...||.||:.           .:.::..|..:.:...|...|::|.:|:|.::..
Human   297 ACGGNTLYPGFTKRLFRELM-----------GDHVSSTKATVWEGSNRNFSVWLGASVVAHLSTY 350

  Fly   373 RDGFWMSKQEYQE 385
            :.. |||::||.|
Human   351 QSE-WMSREEYGE 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp2	NP_001259621.1	ACTIN	6..393	CDD:214592	118/403 (29%)
ACTL8	NP_110439.2	ACTIN	4..363	CDD:214592	118/403 (29%)
		NBD_sugar-kinase_HSP70_actin	7..362	CDD:302596	115/398 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820