DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arp2 and Actl9

DIOPT Version :9

Sequence 1:	NP_001259621.1	Gene:	Arp2 / 32623	FlyBaseID:	FBgn0011742	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_899105.2	Gene:	Actl9 / 69481	MGIID:	1916731	Length:	415	Species:	Mus musculus

Alignment Length:	387	Identity:	119/387 - (30%)
Similarity:	210/387 - (54%)	Gaps:	27/387 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 IVCDNGTGFVKCGYAGSNFPTHIFPSMVG-RPMIRAVNKIGDIEVKDLHVDDLMVGDEASQLRSL 72
            :|.|.|||..|.|:||.:.||:...:::| :|..:|.....::|.        .:| ||::.|..
Mouse    51 VVIDMGTGTCKVGFAGQSQPTYTVATILGCQPKKQATKDQSELET--------FIG-EAARSRPE 106

  Fly    73 LEVSYPMENGVVRNWDDMCHVWDYTFGPKKMDIDPTNTKILLTEPPMNPTKNREKMIEVMFEKYG 137
            |.:..|:.||:|.:|:....:|.:.. ...:.:......:|.::||.:|..||||::||.||...
Mouse   107 LRLVKPIRNGIVVDWEAAELIWRHIL-EHDLQVATHEHPLLFSDPPFSPATNREKLVEVAFESLH 170

  Fly   138 FDSAYIAIQAVLTLYAQGLISGVVIDSGDGVTHICPVYEEFALPHLTRRLDIAGRDITRYLIKLL 202
            ..:.|:|.|:||::||.|.::|:|:|:|.||::..||.:.:.|||..:|||:||..:|.:|.::|
Mouse   171 SPALYVASQSVLSVYAHGRVNGLVVDTGHGVSYTVPVVQGYNLPHAIQRLDLAGNHLTAFLAEML 235

  Fly   203 LLRGYAFNHSADFETVRIMKEKLCYIGYDIEMEQRLALETTVLVESYTLPDGRVIKVGGERFEAP 267
            |..|::.... |.:.|..:|...||:..|.:.||  |.......:|..|||||.:.:|.|.|:.|
Mouse   236 LGSGFSLQQE-DLDLVENIKHHYCYLAPDFQKEQ--ARPDEECKQSLKLPDGRTVTLGKELFQCP 297

  Fly   268 EALFQPHLINVEGP-GIAELAFNTIQAADIDIRPELYKHIVLSGGSTMYPGLPSRLEREIKQLYL 331
            |.||.|..|....| |:..:|..::.....::||.:.::::|.|||:::.||..|...|:    |
Mouse   298 ELLFHPPEIPGLSPIGLPAMAEQSLLKVPQELRPHVARNVILCGGSSLFTGLEGRFRAEL----L 358

  Fly   332 ERVLKNDTEKLAKFKIRIEDPPRRKDMVFIGGAVLAEVTKDRDGFWMSKQEYQEQGLKVLQK 393
            ..:...|       .:.:...|.|...|:|||::||.:...: ..|:.:::|:|:|.:|:.:
Mouse   359 HSLSPED-------HVVVMAHPNRNLSVWIGGSILASLHAFQ-SCWVLREQYEERGPQVVYR 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp2	NP_001259621.1	ACTIN	6..393	CDD:214592	119/385 (31%)
Actl9	NP_899105.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
Actl9	NP_899105.2	ACTIN	48..414	CDD:214592	119/387 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910