Protein Alignment Arp2 and ACTB

DIOPT Version :10

• Sequence 1: NP_001259621.1
• Gene: Arp2 / 32623
• FlyBaseID: FBgn0011742
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: NP_001092.1
• Gene: ACTB / 60
• HGNCID: 132
• Length: 375
• Species: Homo sapiens
• Alignment Length: 385
• Identity: 182/385 - (47%)
• Similarity: 251/385 - (65%)
• Gaps: 20/385 - (5%)

  Fly     9 IVCDNGTGFVKCGYAGSNFPTHIFPSMVGRPMIRAVNKIGDIEVKDLHVDDLMVGDEASQLRSLL 73
            :|.|||:|..|.|:||.:.|..:|||:||||..:.| .:|      :...|..|||||...|.:|
Human     8 LVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGV-MVG------MGQKDSYVGDEAQSKRGIL 65

  Fly    74 EVSYPMENGVVRNWDDMCHVWDYTFGPKKMDIDPTNTKILLTEPPMNPTKNREKMIEVMFEKYGF 138
            .:.||:|:|:|.|||||..:|.:|| ..::.:.|....:||||.|:||..|||||.::|||.:..
Human    66 TLKYPIEHGIVTNWDDMEKIWHHTF-YNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNT 129

  Fly   139 DSAYIAIQAVLTLYAQGLISGVVIDSGDGVTHICPVYEEFALPHLTRRLDIAGRDITRYLIKLLL 203
            .:.|:||||||:|||.|..:|:|:||||||||..|:||.:||||...|||:||||:|.||:|:|.
Human   130 PAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILT 194

  Fly   204 LRGYAFNHSADFETVRIMKEKLCYIGYDIEMEQRLALETTVLVESYTLPDGRVIKVGGERFEAPE 268
            .|||:|..:|:.|.||.:||||||:..|.|.|...|..::.|.:||.||||:||.:|.|||..||
Human   195 ERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPE 259

  Fly   269 ALFQPHLINVEGPGIAELAFNTIQAADIDIRPELYKHIVLSGGSTMYPGLPSRLEREIKQLYLER 333
            |||||..:.:|..||.|..||:|...|:|||.:||.:.|||||:|||||:..|:::||..|
Human   260 ALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITAL---- 320

  Fly   334 VLKNDTEKLAKFKIRIEDPPRRKDMVFIGGAVLAEVTKDRDGFWMSKQEYQEQGLKVLQK 393
                   ..:..||:|..||.||..|:|||::||.::..:. .|:|||||.|.|..::.:
Human   321 -------APSTMKIKIIAPPERKYSVWIGGSILASLSTFQQ-MWISKQEYDESGPSIVHR 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp2	NP_001259621.1	ASKHA_NBD_Arp2	7..393	CDD:466821	182/383 (48%)
ACTB	NP_001092.1	ASKHA_NBD_actin	6..370	CDD:466823	182/381 (48%)