DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arp2 and arp2

DIOPT Version :9

Sequence 1:	NP_001259621.1	Gene:	Arp2 / 32623	FlyBaseID:	FBgn0011742	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_001342919.1	Gene:	arp2 / 5802965	PomBaseID:	SPAC11H11.06	Length:	390	Species:	Schizosaccharomyces pombe

Alignment Length:	386	Identity:	249/386 - (64%)
Similarity:	304/386 - (78%)	Gaps:	6/386 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 IVCDNGTGFVKCGYAGSNFPTHIFPSMVGRPMIRAVNKIGDIEVKDLHVDDLMVGDEASQLRSLL 73
            ||.||||||||.|||..|||...|||:||||::||..|.|::::|     |:||||||..:||||
pombe     6 IVLDNGTGFVKVGYAKDNFPRFQFPSIVGRPILRAEEKTGNVQIK-----DVMVGDEAEAVRSLL 65

  Fly    74 EVSYPMENGVVRNWDDMCHVWDYTFGPKKMDIDPTNTKILLTEPPMNPTKNREKMIEVMFEKYGF 138
            :|.||||||::|::::|..:|||||. :|:.|||...|||||||||||..|||||.|.|||:|||
pombe    66 QVKYPMENGIIRDFEEMNQLWDYTFF-EKLKIDPRGRKILLTEPPMNPVANREKMCETMFERYGF 129

  Fly   139 DSAYIAIQAVLTLYAQGLISGVVIDSGDGVTHICPVYEEFALPHLTRRLDIAGRDITRYLIKLLL 203
            ...|:||||||:||||||.||||:|||||||||.||||...|.||..|||:||||.|||||.|||
pombe   130 GGVYVAIQAVLSLYAQGLSSGVVVDSGDGVTHIVPVYESVVLNHLVGRLDVAGRDATRYLISLLL 194

  Fly   204 LRGYAFNHSADFETVRIMKEKLCYIGYDIEMEQRLALETTVLVESYTLPDGRVIKVGGERFEAPE 268
            .:|||||.:|||||||.|||||||:.||:|::.:|:.|||||:.:||||||||||||.||:|.||
pombe   195 RKGYAFNRTADFETVREMKEKLCYVSYDLELDHKLSEETTVLMRNYTLPDGRVIKVGSERYECPE 259

  Fly   269 ALFQPHLINVEGPGIAELAFNTIQAADIDIRPELYKHIVLSGGSTMYPGLPSRLEREIKQLYLER 333
            .||||||:..|.||::|..|:||||||:|||..||:.|||||||:||.|||||||:|||||:.||
pombe   260 CLFQPHLVGSEQPGLSEFIFDTIQAADVDIRKYLYRAIVLSGGSSMYAGLPSRLEKEIKQLWFER 324

  Fly   334 VLKNDTEKLAKFKIRIEDPPRRKDMVFIGGAVLAEVTKDRDGFWMSKQEYQEQGLKVLQKL 394
            ||..|..:|..||::|||.|||:..|||||||||::....|..|:||.|::|.|::.|.||
pombe   325 VLHGDPARLPNFKVKIEDAPRRRHAVFIGGAVLADIMAQNDHMWVSKAEWEEYGVRALDKL 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp2	NP_001259621.1	ACTIN	6..393	CDD:214592	247/383 (64%)
arp2	NP_001342919.1	ACTIN	4..382	CDD:214592	246/381 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	509	1.000	Domainoid score	I54
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4181
Inparanoid	1	1.050	511	1.000	Inparanoid score	I233
OMA	1	1.010	-	-		QHG54319
OrthoFinder	1	1.000	-	-		FOG0003456
OrthoInspector	1	1.000	-	-		oto102080
orthoMCL	1	0.900	-	-		OOG6_102757
Panther	1	1.100	-	-	LDO	PTHR11937
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R82
SonicParanoid	1	1.000	-	-		X2348
TreeFam	1	0.960	-	-
	14	13.860