Protein Alignment Arp2 and ACTBL2

DIOPT Version :9

• Sequence 1: NP_001259621.1
• Gene: Arp2 / 32623
• FlyBaseID: FBgn0011742
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: NP_001017992.1
• Gene: ACTBL2 / 345651
• HGNCID: 17780
• Length: 376
• Species: Homo sapiens
• Alignment Length: 387
• Identity: 183/387 - (47%)
• Similarity: 249/387 - (64%)
• Gaps: 20/387 - (5%)

  Fly     7 NVIVCDNGTGFVKCGYAGSNFPTHIFPSMVGRPMIRAVNKIGDIEVKDLHVDDLMVGDEASQLRS 71
            :.:|.|||:|..|.|:.|.:.|..:||||:|||..:.| .:|      :...|..|||||...|.
Human     7 SALVVDNGSGMCKAGFGGDDAPRAVFPSMIGRPRHQGV-MVG------MGQKDCYVGDEAQSKRG 64

  Fly    72 LLEVSYPMENGVVRNWDDMCHVWDYTFGPKKMDIDPTNTKILLTEPPMNPTKNREKMIEVMFEKY 136
            :|.:.||:|:|||.|||||..:|.:|| ..::.:.|....|||||.|:||..|||||.::|||.:
Human    65 VLTLKYPIEHGVVTNWDDMEKIWYHTF-YNELRVAPDEHPILLTEAPLNPKINREKMTQIMFEAF 128

  Fly   137 GFDSAYIAIQAVLTLYAQGLISGVVIDSGDGVTHICPVYEEFALPHLTRRLDIAGRDITRYLIKL 201
            ...:.|:||||||:|||.|..:|:|:|||||||||.|:||.:||||...|||:||||:|.||:|:
Human   129 NTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHIVPIYEGYALPHAILRLDLAGRDLTDYLMKI 193

  Fly   202 LLLRGYAFNHSADFETVRIMKEKLCYIGYDIEMEQRLALETTVLVESYTLPDGRVIKVGGERFEA 266
            |..|||.|..:|:.|.||.:||||||:..|.|.|...|..::....||.||||:||.:|.|||..
Human   194 LTERGYNFTTTAEREIVRDVKEKLCYVALDFEQEMVRAAASSSPERSYELPDGQVITIGNERFRC 258

  Fly   267 PEALFQPHLINVEGPGIAELAFNTIQAADIDIRPELYKHIVLSGGSTMYPGLPSRLEREIKQLYL 331
            |||:|||..:.:|..||.|..||:|...|:|||.:||.:.|||||||||||:..|:::||..|
Human   259 PEAIFQPSFLGIESSGIHETTFNSIMKCDVDIRKDLYANTVLSGGSTMYPGIADRMQKEIITL-- 321

  Fly   332 ERVLKNDTEKLAKFKIRIEDPPRRKDMVFIGGAVLAEVTKDRDGFWMSKQEYQEQGLKVLQK 393
                     ..:..||:|..||.||..|:|||::||.::..:. .|:|||||.|.|..::.:
Human   322 ---------APSTMKIKIIAPPERKYSVWIGGSILASLSTFQQ-MWISKQEYDEAGPPIVHR 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp2	NP_001259621.1	ACTIN	6..393	CDD:214592	183/385 (48%)
ACTBL2	NP_001017992.1	NBD_sugar-kinase_HSP70_actin	1..376	CDD:327376	183/387 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820