DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arp2 and Actc1

DIOPT Version :9

Sequence 1:	NP_001259621.1	Gene:	Arp2 / 32623	FlyBaseID:	FBgn0011742	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_062056.1	Gene:	Actc1 / 29275	RGDID:	2026	Length:	377	Species:	Rattus norvegicus

Alignment Length:	392	Identity:	184/392 - (46%)
Similarity:	253/392 - (64%)	Gaps:	20/392 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DSKGRNVIVCDNGTGFVKCGYAGSNFPTHIFPSMVGRPMIRAVNKIGDIEVKDLHVDDLMVGDEA 66
            |.:....:|||||:|.||.|:||.:.|..:|||:||||..:.| .:|      :...|..|||||
  Rat     3 DDEETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGV-MVG------MGQKDSYVGDEA 60

  Fly    67 SQLRSLLEVSYPMENGVVRNWDDMCHVWDYTFGPKKMDIDPTNTKILLTEPPMNPTKNREKMIEV 131
            ...|.:|.:.||:|:|::.|||||..:|.:|| ..::.:.|.....||||.|:||..|||||.::
  Rat    61 QSKRGILTLKYPIEHGIITNWDDMEKIWHHTF-YNELRVAPEEHPTLLTEAPLNPKANREKMTQI 124

  Fly   132 MFEKYGFDSAYIAIQAVLTLYAQGLISGVVIDSGDGVTHICPVYEEFALPHLTRRLDIAGRDITR 196
            |||.:...:.|:||||||:|||.|..:|:|:||||||||..|:||.:||||...|||:||||:|.
  Rat   125 MFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTD 189

  Fly   197 YLIKLLLLRGYAFNHSADFETVRIMKEKLCYIGYDIEMEQRLALETTVLVESYTLPDGRVIKVGG 261
            ||:|:|..|||:|..:|:.|.||.:||||||:..|.|.|...|..::.|.:||.||||:||.:|.
  Rat   190 YLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGN 254

  Fly   262 ERFEAPEALFQPHLINVEGPGIAELAFNTIQAADIDIRPELYKHIVLSGGSTMYPGLPSRLEREI 326
            |||..||.||||..|.:|..||.|..:|:|...|||||.:||.:.|||||:|||||:..|:::||
  Rat   255 ERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEI 319

  Fly   327 KQLYLERVLKNDTEKLAKFKIRIEDPPRRKDMVFIGGAVLAEVTKDRDGFWMSKQEYQEQGLKVL 391
            ..|           ..:..||:|..||.||..|:|||::||.::..:. .|:|||||.|.|..::
  Rat   320 TAL-----------APSTMKIKIIAPPERKYSVWIGGSILASLSTFQQ-MWISKQEYDEAGPSIV 372

  Fly   392 QK 393
            .:
  Rat   373 HR 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp2	NP_001259621.1	ACTIN	6..393	CDD:214592	183/386 (47%)
Actc1	NP_062056.1	PTZ00281	4..377	CDD:173506	183/391 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820