DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arp2 and Actr2

DIOPT Version :9

Sequence 1:	NP_001259621.1	Gene:	Arp2 / 32623	FlyBaseID:	FBgn0011742	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	XP_017454617.1	Gene:	Actr2 / 289820	RGDID:	1310826	Length:	399	Species:	Rattus norvegicus

Alignment Length:	394	Identity:	320/394 - (81%)
Similarity:	365/394 - (92%)	Gaps:	0/394 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDSKGRNVIVCDNGTGFVKCGYAGSNFPTHIFPSMVGRPMIRAVNKIGDIEVKDLHVDDLMVGDE 65
            |||:||.|:|||||||||||||||||||.||||::||||:||:..|:|:||:|:....|||||||
  Rat     1 MDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKNNKKMDLMVGDE 65

  Fly    66 ASQLRSLLEVSYPMENGVVRNWDDMCHVWDYTFGPKKMDIDPTNTKILLTEPPMNPTKNREKMIE 130
            ||:|||:|||:||||||:|||||||.|:|||||||:|::||..:.|||||||||||||||||::|
  Rat    66 ASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRSCKILLTEPPMNPTKNREKIVE 130

  Fly   131 VMFEKYGFDSAYIAIQAVLTLYAQGLISGVVIDSGDGVTHICPVYEEFALPHLTRRLDIAGRDIT 195
            ||||.|.|...|:|||||||||||||::|||:||||||||||||||.|:||||||||||||||||
  Rat   131 VMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDIT 195

  Fly   196 RYLIKLLLLRGYAFNHSADFETVRIMKEKLCYIGYDIEMEQRLALETTVLVESYTLPDGRVIKVG 260
            ||||||||||||||||||||||||::||||||:||:||.||:||||||||||||||||||:||||
  Rat   196 RYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVG 260

  Fly   261 GERFEAPEALFQPHLINVEGPGIAELAFNTIQAADIDIRPELYKHIVLSGGSTMYPGLPSRLERE 325
            ||||||||||||||||||||.|:|||.||||||||||.|.|.|||||||||||||||||||||||
  Rat   261 GERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERE 325

  Fly   326 IKQLYLERVLKNDTEKLAKFKIRIEDPPRRKDMVFIGGAVLAEVTKDRDGFWMSKQEYQEQGLKV 390
            :||||||||||.|.|||:|||||||||||||.|||:||||||::.||:|.|||::|||||:|::|
  Rat   326 LKQLYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRV 390

  Fly   391 LQKL 394
            |:||
  Rat   391 LEKL 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp2	NP_001259621.1	ACTIN	6..393	CDD:214592	314/386 (81%)
Actr2	XP_017454617.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334372
Domainoid	1	1.000	663	1.000	Domainoid score	I146
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4181
Inparanoid	1	1.050	673	1.000	Inparanoid score	I701
OMA	1	1.010	-	-		QHG54319
OrthoDB	1	1.010	-	-		D280976at33208
OrthoFinder	1	1.000	-	-		FOG0003456
OrthoInspector	1	1.000	-	-		oto98718
orthoMCL	1	0.900	-	-		OOG6_102757
Panther	1	1.100	-	-	LDO	PTHR11937
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2348
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770