Protein Alignment Arp2 and ACTR1B

DIOPT Version :9

• Sequence 1: NP_001259621.1
• Gene: Arp2 / 32623
• FlyBaseID: FBgn0011742
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: NP_005726.1
• Gene: ACTR1B / 10120
• HGNCID: 168
• Length: 376
• Species: Homo sapiens
• Alignment Length: 388
• Identity: 169/388 - (43%)
• Similarity: 239/388 - (61%)
• Gaps: 29/388 - (7%)

  Fly     9 IVCDNGTGFVKCGYAGSNFPTHIFPSMVGRPMIRAVNKIGDIEVKDLHVDDLMVGDEASQLRSLL 73
            :|.|||:|.:|.|:||...|.:.||:.||||....| ..|.:|      .||.:|.:|.:.|.||
Human    12 VVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRV-MAGALE------GDLFIGPKAEEHRGLL 69

  Fly    74 EVSYPMENGVVRNWDDMCHVWDYTFGPKKMDIDPTNTKILLTEPPMNPTKNREKMIEVMFEKYGF 138
            .:.||||:||||:|:||..:|.|.:...::........:||||.|:||:|||||..||.||.:..
Human    70 TIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNREKAAEVFFETFNV 134

  Fly   139 DSAYIAIQAVLTLYAQGLISGVVIDSGDGVTHICPVYEEFALPHLTRRLDIAGRDITRYLIKLLL 203
            .:.:|::||||:|||.|..:|||:||||||||..|:||.||:||...|:||||||::|||..||.
Human   135 PALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVSRYLRLLLR 199

  Fly   204 LRGYAFNHSADFETVRIMKEKLCYIGYDIEMEQRLALETTVLVESYTLPDGRVIKVGGERFEAPE 268
            ..|..|:.||:||.||.:||:.||:..:.:.::  ||||..:  .||||||..:.||..||.|||
Human   200 KEGVDFHTSAEFEVVRTIKERACYLSINPQKDE--ALETEKV--QYTLPDGSTLDVGPARFRAPE 260

  Fly   269 ALFQPHLINVEGPGIAELAFNTIQAADIDIRPELYKHIVLSGGSTMYPGLPSRLEREIKQLYLER 333
            .||||.|:..|..|:.|:....|..:|:|:|..|:.:||||||||::.|...||..|:|:|..:.
Human   261 LLFQPDLVGDESEGLHEVVAFAIHKSDMDLRRTLFANIVLSGGSTLFKGFGDRLLSEVKKLAPKD 325

  Fly   334 VLKNDTEKLAKFKIRIEDPPRRKDMVFIGGAVLAEVTKDRDGF---WMSKQEYQEQGLKVLQK 393
            :           ||:|..|..|....:|||::||.:    |.|   |:||:||:|.|.:.:.:
Human   326 I-----------KIKISAPQERLYSTWIGGSILASL----DTFKKMWVSKKEYEEDGSRAIHR 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp2	NP_001259621.1	ACTIN	6..393	CDD:214592	169/386 (44%)
ACTR1B	NP_005726.1	NBD_sugar-kinase_HSP70_actin	5..376	CDD:418402	169/388 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820