Protein Alignment CG32669 and SLC5A6

DIOPT Version :10

• Sequence 1: NP_727460.1
• Gene: CG32669 / 326229
• FlyBaseID: FBgn0052669
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_066918.2
• Gene: SLC5A6 / 8884
• HGNCID: 11041
• Length: 635
• Species: Homo sapiens
• Alignment Length: 572
• Identity: 219/572 - (38%)
• Similarity: 327/572 - (57%)
• Gaps: 42/572 - (7%)

  Fly     1 MATLGAWDYTILAVVLIISVAIGIYYRFVGGKQSTTTEYLLADRSMNVAPVAFSLMASFMSAVTI 65
            |:|....||.:..::|::|:|||:|:...|..:.|..|.|:|||.|...|||.||:|:|.|||.|
Human    21 MSTFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSAVAI 85

  Fly    66 LGVSMENYQYGTMFVVINLSYVLSTPVAAYLIIPVFYRLKTASVYEYLELRFGYATRLAASLSFS 130
            |||..|.|::||.:..:...|.|...:.|::.|||||||...|.||||||||....|:..:::|.
Human    86 LGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYLELRFNKTVRVCGTVTFI 150

  Fly   131 LQMVLYMGIVVYAPALALEAVTGLSQVFSIVIVGVVCTFYATLGGMKAVLITDIYQSLLMFAAVF 195
            .|||:|||:|:|||:|||.||||.....|::.:|:|||.|..|||:|||:.||::|:|:||....
Human   151 FQMVIYMGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAVIWTDVFQTLVMFLGQL 215

  Fly   196 SVIICAWVKAGSLEVIWRVAQENGRINLTNFSVDPTERHTWFTQILGGCATYLAIYGVNQTQVQR 260
            :|||....|.|.|..:|.||.::|||:......||..|||::|...||....|::|||||.||||
Human   216 AVIIVGSAKVGGLGRVWAVASQHGRISGFELDPDPFVRHTFWTLAFGGVFMMLSLYGVNQAQVQR 280

  Fly   261 LMAVKSLSAARAALWWCLPI----LCLLSLSTCFSGLCIYWYYRDCDPLLEGRVNSRDQVMPLFV 321
            .::.::..||..:.:...|.    ||:    .|..||.::.||::....::....:.||.:..||
Human   281 YLSSRTEKAAVLSCYAVFPFQQVSLCV----GCLIGLVMFAYYQEYPMSIQQAQAAPDQFVLYFV 341

  Fly   322 VDTMGEYTGLAGLFVSGIFCASLSTISSIISSLAAVTLEDYLKPLVSCCAKRTLTDRQTLWYSKL 386
            :|.:....||.|||::.:|..|||||||..:|||.||:||.::|...     ..::.:.:..|:.
Human   342 MDLLKGLPGLPGLFIACLFSGSLSTISSAFNSLATVTMEDLIRPWFP-----EFSEARAIMLSRG 401

  Fly   387 LSLFFGALCIGMAFMAGSIGGLLQAALSIFGIIGGPLLGLFTLGMYVTKANEKGAIGGLLISLAF 451
            |:..:|.||:|||:::..:|.:||||:||||::||||||||.|||:...||..||:.|||..|..
Human   402 LAFGYGLLCLGMAYISSQMGPVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVM 466

  Fly   452 CFWIG-------FGQPKPPLVSLDMSTAGCPVDRSFARDIFLKTVIAVAEEEHYFYLYRISYMWY 509
            .||||       .|...||..| :.|:...|.:.:.|....|..:...::.......|.:||:||
Human   467 AFWIGIGSIVTSMGSSMPPSPS-NGSSFSLPTNLTVATVTTLMPLTTFSKPTGLQRFYSLSYLWY 530

  Fly   510 AA--------LGFLITFFGGWL-------------LSWLFALLKWDNNRRIY 540
            :|        :|.:::...|.:             |..|.:||.....:|::
Human   531 SAHNSTTVIVVGLIVSLLTGRMRGRSLNPATIYPVLPKLLSLLPLSCQKRLH 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32669	NP_727460.1	SLC5sbd_NIS-SMVT	7..527	CDD:271383	213/551 (39%)
SLC5A6	NP_066918.2	SLC5sbd_SMVT	24..550	CDD:271394	211/535 (39%)