Protein Alignment CG32669 and SLC5A2

DIOPT Version :9

• Sequence 1: NP_727460.1
• Gene: CG32669 / 326229
• FlyBaseID: FBgn0052669
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: XP_006721135.2
• Gene: SLC5A2 / 6524
• HGNCID: 11037
• Length: 705
• Species: Homo sapiens
• Alignment Length: 589
• Identity: 134/589 - (22%)
• Similarity: 240/589 - (40%)
• Gaps: 133/589 - (22%)

  Fly     8 DYTILAVVLIISVAIGIYYRFVGGKQSTTTEYLLADRSMNVAPVAFSLMASFMSAVTIL------ 66
            |..::|...::.:.:|: :......:.|...|.||.|||...||..||.||.:.:...:
Human    32 DILVIAAYFLLVIGVGL-WSMCRTNRGTVGGYFLAGRSMVWWPVGASLFASNIGSGHFVGLAGTG 95

  Fly    67 ---GVSMENYQYGTMFVVINLSYVLSTPVAAYLIIPVFYRLKTASVYEYLELRFGYATRLAASLS 128
               |:::..:::..:|||:.|         .:|..||:......::.:||..||| ..|:...||
Human    96 AASGLAVAGFEWNALFVVLLL---------GWLFAPVYLTAGVITMPQYLRKRFG-GRRIRLYLS 150

  Fly   129 FSLQMVLY----MGIVVYAPALALEAVTGLSQVFSIVIVGVVCTFYATLGGMKAVLITDIYQSLL 189
            . |.:.||    :.:.:::.|:.::...|.:...|::.:..:...|...||:.|::.||..|:.:
Human   151 V-LSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAALMYTDTVQTFV 214

  Fly   190 MFAAVFSVIICAWVKAGSLEVIW----------RVAQENGRINLTNFSVDPTE------RH---- 234
            :......::..|:.:.|....::          .|:::....|:::|...|..      ||
Human   215 ILGGACILMGYAFHEVGGYSGLFDKYLGAATSLTVSEDPAVGNISSFCYRPRPDSYHLLRHPVTG 279

  Fly   235 --TWFTQILGGCATYLAIYGVNQTQVQRLMAVKSLSAARAALWWCLPILC-LLSLSTCF----SG 292
              .|...:||........:..:|..|||.:|.|||:..:|.   |  ||| .|.|:..|    .|
Human   280 DLPWPALLLGLTIVSGWYWCSDQVIVQRCLAGKSLTHIKAG---C--ILCGYLKLTPMFLMVMPG 339

  Fly   293 LCIYWYYRD---------CDPLLEGRVNSRDQVMPLFVVDTMGEYTGLAGLFVSGIFCASLSTIS 348
            :.....|.|         |..:....|...:...|..||..|.  .||.||.::.:..|.:|:::
Human   340 MISRILYPDEVACVVPEVCRRVCGTEVGCSNIAYPRLVVKLMP--NGLRGLMLAVMLAALMSSLA 402

  Fly   349 SIISSLAAV-TLEDY--LKPLVSCCAKRTLTDRQTLWYSKLLSLFFGALCIG-----MAFMAGSI 405
            ||.:|.:.: |::.|  |:|...        ||:.|...:|..:|...:.:.     .|...|.:
Human   403 SIFNSSSTLFTMDIYTRLRPRAG--------DRELLLVGRLWVVFIVVVSVAWLPVVQAAQGGQL 459

  Fly   406 GGLLQAALSIFGIIGGPLLGLFTLGMYVTKANEKGA----IGGLLISLA-----FCFWIGFGQPK 461
            ...:||..|   .:..|:..:|.|.::|.:.||:||    |||||:.||     |.|  |.|...
Human   460 FDYIQAVSS---YLAPPVSAVFVLALFVPRVNEQGAFWGLIGGLLMGLARLIPEFSF--GSGSCV 519

  Fly   462 PPLVSLDMSTAGCPVDRSFARDIFLKTVIAVAEEEHYFYLYRISYMWYAALGFLITFFGGWLLSW 526
            .|        :.||.                       :|..:.|:::|    ::.||...||:.
Human   520 QP--------SACPA-----------------------FLCGVHYLYFA----IVLFFCSGLLTL 549

  Fly   527 LFAL 530
            ..:|
Human   550 TVSL 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32669	NP_727460.1	SLC5sbd_NIS-SMVT	7..527	CDD:271383	133/584 (23%)
SLC5A2	XP_006721135.2	SLC5sbd_SGLT2	31..705	CDD:212056	134/589 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810