Protein Alignment CG32669 and Slc5a7

DIOPT Version :9

• Sequence 1: NP_727460.1
• Gene: CG32669 / 326229
• FlyBaseID: FBgn0052669
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_071308.2
• Gene: Slc5a7 / 63993
• MGIID: 1927126
• Length: 580
• Species: Mus musculus
• Alignment Length: 645
• Identity: 116/645 - (17%)
• Similarity: 227/645 - (35%)
• Gaps: 202/645 - (31%)

  Fly    11 ILAVVL--IISVAIGIYYRF----VGGKQSTTTEYLLADRSMNVAPVAFSLMASFMSAVTILGVS 69
            ::|::|  ::...:||:..:    .|..:..:...::..|.:.:....|::.|:::....|.|.:
Mouse     8 LVAIILFYLLIFLVGIWAAWKTKNSGNPEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTA 72

  Fly    70 MENY--QYGTMFVVINLSYVLSTPVAAYLII-PVFYRLKTASVYEYLELRFGYATRLAASLSFSL 131
            ...|  ..|..:....:.|.||      ||: .:|:.....|.        ||.|.|.     ..
Mouse    73 EAVYGPGCGLAWAQAPIGYSLS------LILGGLFFAKPMRSK--------GYVTMLD-----PF 118

  Fly   132 QMVL--YMGIVVYAPAL----------------ALEAVTGLSQVFSIVIVGVVCTFYATLGGMKA 178
            |.:.  .||.:::.|||                .:..:..:....|:::..::...|..:||:.:
Mouse   119 QQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDVNISVIVSALIAILYTLVGGLYS 183

  Fly   179 VLITDIYQSLLMFAAVFSVIICAWVKAGSLEVIWRVAQENGRINLTNF-------------SVDP 230
            |..||:.|       :|.:.|..|:..       ..|..:..:....|             :::.
Mouse   184 VAYTDVVQ-------LFCIFIGLWISV-------PFALSHPAVTDIGFTAVHAKYQSPWLGTIES 234

  Fly   231 TERHTWFTQILGGCATYLAIYGVN-QTQVQRLMA--------VKSLSAARAALWWCLPILCLLSL 286
            .|.:||....|     .|.:.|:. |...||:::        |.|..||...|...||.:|:.::
Mouse   235 VEVYTWLDNFL-----LLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMALPAICIGAI 294

  Fly   287 STCFSGLCIYW---YYRDCDPLLEGRVNSRDQVMPLFVVDTMGEYTGLAGLFVS--GIFCASLST 346
                 |....|   .|...||..:   ...|.::|:.:     :|  |..:::|  |:...|.:.
Mouse   295 -----GASTDWNQTAYGYPDPKTK---EEADMILPIVL-----QY--LCPVYISFFGLGAVSAAV 344

  Fly   347 ISSIISSLAAVTLEDYLKPLVSCCAKRTLTDRQTLWYSKLLSLFFGALCIGMAFMAGSIGGLLQA 411
            :||..||:.:.: ..:.:.:.....::..:|::.:|..::..|.|||....||.:..::.||...
Mouse   345 MSSADSSILSAS-SMFARNIYQLSFRQNASDKEIVWVMRITVLVFGASATAMALLTKTVYGLWYL 408

  Fly   412 ALSIFGIIGGPLLGLFTLGMYVTKANEKGAIGGLLISLAFCFWIGFGQPKPPLVSLDMSTAGCPV 476
            :..:..||..|.|   ...:::...|..||:.|.:          ||
Mouse   409 SSDLVYIIIFPQL---LCVLFIKGTNTYGAVAGYI----------FG------------------ 442

  Fly   477 DRSFARDIFLKTVIAVAEEEHYFYLYRISYMWYAALGFLITFFGGWLLSWLFALLKWDNNRRIYQ 541
                   :||:    :...|.|.||..            :.|:.|:                 |.
Mouse   443 -------LFLR----ITGGEPYLYLQP------------LIFYPGY-----------------YS 467

  Fly   542 DADCTLIKHDLFVPPIAKRLQRRQMPLLVVTGTSSEIGGITT--------ESATAPPRLD 593
            |      |:.::         .::.|...::..:|....|..        ||.|.||:||
Mouse   468 D------KNGIY---------NQRFPFKTLSMVTSFFTNICVSYLAKYLFESGTLPPKLD 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32669	NP_727460.1	SLC5sbd_NIS-SMVT	7..527	CDD:271383	103/569 (18%)
Slc5a7	NP_071308.2	SLC5sbd_CHT	8..495	CDD:271368	109/626 (17%)
		Mediates interaction with SEC14L1. /evidence=ECO:0000250|UniProtKB:Q9JMD7	502..580		7/11 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900