DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32669 and Smvt

DIOPT Version :9

Sequence 1:	NP_727460.1	Gene:	CG32669 / 326229	FlyBaseID:	FBgn0052669	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_651891.2	Gene:	Smvt / 43744	FlyBaseID:	FBgn0039873	Length:	591	Species:	Drosophila melanogaster

Alignment Length:	541	Identity:	186/541 - (34%)
Similarity:	285/541 - (52%)	Gaps:	37/541 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 AWDYTILAVVLIISVAIGIYYRFVGGKQSTTTEYLLADRSMNVAPVAFSLMASFMSAVTILGVSM 70
            |.||.:.|:||.||.|||:|:.|....:.||.|||:..:.|...|:|.||:||.:||::|:.:..
  Fly    26 ATDYGVFALVLSISAAIGVYFGFFAKGEDTTEEYLMGGKRMKTIPIAISLVASQLSAISIMTIPA 90

  Fly    71 ENYQYGTMFVVINLSYVLSTPVAAYLIIPVFYRLKTASVYEYLELRFGYATRLAASLSFSLQMVL 135
            |.|.||..:|...:..||..|:..||:|||||.....:.|||||:||....|:..:..|.|.|..
  Fly    91 EMYAYGINWVFNVVCMVLVVPLLNYLVIPVFYNNNITNCYEYLEMRFCRKVRVLQTFIFILTMFF 155

  Fly   136 YMGIVVYAPALALEAVTGLSQVFSIVIVGVVCTFYATLGGMKAVLITDIYQSLLMFAAVFSVIIC 200
            .:.|.::.|:||...|||.:......:|..:|.||...||:|||:.||:.|:.:|.|:|..|.:.
  Fly   156 MLPIFIFLPSLAFAQVTGFNVHLINTVVCSICVFYTMFGGIKAVVWTDVIQAAIMVASVVLVGVL 220

  Fly   201 AWVKAGSLEVIWRVAQENGRINLTNFSVDPTERHTWFTQILGGCATYLAIYGVNQTQVQRLMAVK 265
            ...:.|....:.|:|.|.||::: |::.|.|.|.|.:.........:....|:||:.|||::::.
  Fly   221 GAHRVGGFFEVLRIAGEGGRLDI-NYNFDLTTRSTIWNIFTSATMMWTGYVGLNQSCVQRIVSLP 284

  Fly   266 SLSAARAALWWCLPIL-----CLLSLSTCFSGLCIYWYYRDCDPLLEGRVNSRDQVMPLFVVDTM 325
            ||..||.:|     :|     .|:....||:|:.||..:.||||:..|.|:..|:::|.||.||:
  Fly   285 SLGHARRSL-----VLFGFGFILIMFFNCFTGIVIYSRFHDCDPIQSGHVSKVDKMVPYFVQDTV 344

  Fly   326 GEYTGLAGLFVSGIFCASLSTISSIISSLAAVTLEDYLKPLVSCCAKRTLTDRQTLWYSKLLSLF 390
            |...|:.|:|:|.:|.|:|||:|:.|:||..|...||:||.:      ..|:.:.....||...|
  Fly   345 GNLWGMPGVFISCVFSAALSTLSASINSLGGVVYFDYIKPHI------RHTEHRANVIMKLFVFF 403

  Fly   391 FGALCIGMAFMAGSIGGLLQAALSIFGIIGGPLLGLFTLGMYVTKANEKGAIGGLLISLAFCF-- 453
            .|..||....:..:...:||...||.|:..|...|:|.|||.|.|::.:.|:.|:|.|:| |.
  Fly   404 TGIYCILGGMVIENFNSILQVIYSIGGMSFGSTCGVFMLGMLVPKSHGRAALVGVLASIA-CMAT 467

  Fly   454 -----WIGFGQPKPPLVSLDMSTAGCPV-------DRSFARDIFLKTVIAVAEEEHYFYLYRISY 506
                 |     .:....:|..||:.||.       |.|.|..:||.:.......|..|.:..:|:
  Fly   468 IVILSW-----GRNHYDTLPTSTSACPASLNGTIKDISTASPLFLGSTTEAPVGEKEFSILDLSF 527

  Fly   507 MWYAALGFLITFFGGWLLSWL 527
            .||...||:||:..|..||::
  Fly   528 NWYTVTGFVITWLIGIPLSYI 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32669	NP_727460.1	SLC5sbd_NIS-SMVT	7..527	CDD:271383	185/538 (34%)
Smvt	NP_651891.2	SLC5sbd_NIS-SMVT	27..548	CDD:271383	185/538 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448246
Domainoid	1	1.000	97	1.000	Domainoid score	I370
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I307
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
	10	9.900