DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32669 and CG7720

DIOPT Version :9

Sequence 1:	NP_727460.1	Gene:	CG32669 / 326229	FlyBaseID:	FBgn0052669	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_001163649.1	Gene:	CG7720 / 42257	FlyBaseID:	FBgn0038652	Length:	681	Species:	Drosophila melanogaster

Alignment Length:	650	Identity:	180/650 - (27%)
Similarity:	309/650 - (47%)	Gaps:	81/650 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MATLGAWDYTILAVVLIISVAIGIYYRFVG-GKQSTTTEYLLADRSMNVAPVAFSLMASFMSAVT 64
            ::|:| |||.:..:.:.::|...::.|..| .|:.:..:|:.|...:::..|..|:....:...:
  Fly     5 LSTMG-WDYLMFVLFIALTVLGPLWKRIFGKKKERSKADYVFATGGVSIVAVMISIARGTLGVRS 68

  Fly    65 ILGVSMENYQYGTMFVVINLSYVLSTPVAAYLIIPVFYRLKTASVYEYLELRFGYAT-RLAASLS 128
            :||...|.|..|:....|....:.:.|:..::.:||::.|...|||:|::|||...| |..||.:
  Fly    69 VLGYPSELYYRGSAMWEIIYGMMSAYPIVCFMFVPVYFNLGITSVYQYIDLRFKSRTVRCLASAT 133

  Fly   129 FSLQMVLYMGIVVYAPALALEAVTGLSQVFSIVIVGVVCTFYATLGGMKAVLITDIYQSLLMFAA 193
            :.::.:..:||.||.|::||..|.|:....||..:.|:|.|:..:||:||.:..|:.|::.:...
  Fly   134 YIVRQICNLGITVYTPSVALSTVIGIPYWASITGMAVICIFFTIMGGLKAAINADVIQTVTILVV 198

  Fly   194 VFSVIICAWVKAGSLEVIWRVAQENGRINLTNFSVDPTERHTWFTQILGGCATYLAIYGVNQTQV 258
            ..:|.|...:..|.::.::::.::|||:|..||:.|.|.|....:..||.....|:..|..|..:
  Fly   199 TVAVCIQGTISTGGVKKVYQLNRDNGRLNFWNFTGDMTVRVDTTSAWLGQLFMSLSQIGCQQNFM 263

  Fly   259 QRLMAVKSLSAARAALWWCLPILCLLSLSTCFSGLCIYWYYRDCDPLLEGRVNSRDQVMPLFVVD 323
            ||.:::|||...|..:...:|::......:..||:.||..|.:|||..||.:...|:::|.||.|
  Fly   264 QRYVSLKSLKQVRRVMLTNVPLVFFFFSISWISGMVIYSTYINCDPYAEGYIKKPDEILPFFVED 328

  Fly   324 TMGEYTGLAGLFVSGIFCASLSTISSIISSLAAVTLEDYLKPLVSCCAKRTLTDRQTLWYSKLLS 388
            .:|...|..|:|::.:|..:|..:.|.::|||.|..||::..|...   :.|:|:|.|...|.::
  Fly   329 QLGFLPGFVGIFMATLFNGALCMMVSNLNSLATVIWEDFISQLPKF---KGLSDKQQLRILKSIT 390

  Fly   389 LFFGALCIGMAFMAGSIGGLLQAALSIFGIIGGPLLGLFTLGMYVTKANEKGAIGGLLISLAFCF 453
            :..|.:.:|:||..|.:.|:::::|.:|....|||||.|.|.|.|..||.||...|::.:.||..
  Fly   391 VVCGLIIMGVAFGVGLLAGVIESSLLVFSATSGPLLGCFILAMMVPIANWKGTSAGMVTACAFVL 455

  Fly   454 W-IGFGQ---PKPPLVSLDMSTAGCPVDRSFARDI-------------------------FLKTV 489
            | ||.|.   ...||  |..||.||..| :||:.|                         |:.|.
  Fly   456 WIIGGGMTVTKDNPL--LPTSTDGCTND-TFAQSIGKPIVEQGQMPWLLSHTPIDGFNQSFVPTQ 517

  Fly   490 IAVAEEEHYF-YLYRISYMWYAALGFLITFFGGWLLSWL-----------------FALLKWDNN 536
            ..:|.|.... ..|.||:|:|:.:|..:|...|.::|.|                 |.|.:..:.
  Fly   518 PTIAPERSGLETFYSISFMYYSLIGTALTVIIGTVISLLTQHPDDAYDGKLLHPLIFRLCERFSG 582

  Fly   537 RRIY---------------QDADCTL-------IKHDLFVPPIAKRLQRRQMPLLVVTGTSSEIG 579
            |:.|               .|:..|.       :.|.....|..|   .:..|:.||..||...|
  Fly   583 RKPYYVKHEEESGLNGRSSSDSSATTTTCKAEKVNHGYESSPEDK---EKSSPIAVVFTTSEGTG 644

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32669	NP_727460.1	SLC5sbd_NIS-SMVT	7..527	CDD:271383	162/551 (29%)
CG7720	NP_001163649.1	SLC5sbd_NIS-SMVT	10..556	CDD:271383	162/551 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I2508
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I307
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.970