Protein Alignment CG32669 and slc5a2

DIOPT Version :10

• Sequence 1: NP_727460.1
• Gene: CG32669 / 326229
• FlyBaseID: FBgn0052669
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_998091.1
• Gene: slc5a2 / 405862
• ZFINID: ZDB-GENE-040426-2498
• Length: 662
• Species: Danio rerio
• Alignment Length: 670
• Identity: 146/670 - (21%)
• Similarity: 257/670 - (38%)
• Gaps: 187/670 - (27%)

  Fly     6 AWDYTILAVVLIISVAIGIYYRF------VGGKQSTTTEYLLADRSMNVAPVAFSLMAS------ 58
            |.|.:::.:..::.:|:||:..|      |||       |.||.|:|...||..||.||
Zfish    14 AADISVIIIYFLVVIAVGIWSTFRTNRGTVGG-------YFLAGRTMVWWPVGTSLFASNIGSGH 71

  Fly    59 ---FMSAVTILGVSMENYQYGTMFVVINLSYVLSTPVAAYLIIPVFYRLKTASVYEYLELRFGYA 120
               ........|:::..:::..:|:|:.|.:|         .:||:......::.:||:.||| .
Zfish    72 FVGLAGTAAASGIAVGGFEWNALFIVLLLGWV---------FVPVYLTAGVITMPQYLKKRFG-G 126

  Fly   121 TRLAASLSFSLQMVLY----MGIVVYAPALALEAVTGLSQVFSIVIVGVVCTFYATLGGMKAVLI 181
            :|::..||. :.:.||    :.:.:::.|:.::...|.:...:::.:..:...|...||:.|::.
Zfish   127 SRISLYLSI-ISLFLYIFTKISVDMFSGAVFIQQALGWNIYVAVIALLCITALYTVTGGLAALMY 190

  Fly   182 TDIYQSLLMFAAVFSVIICAWVKAGSLEVIWRVAQENGRINLTNFSVDPTE----RH-------- 234
            ||..|:.::.|..|.::..::.:.|....:  :.:.|..:.....|::|.|    :|
Zfish   191 TDTVQTFVIIAGAFVLMGFSFYEVGGYSAL--LEKYNSSLPSQTLSLNPNEYNISQHCYMPREDA 253

  Fly   235 ------------TWFTQILGGCATYLAIYG-----VNQTQVQRLMAVKSLSAARAALWWC----- 277
                        .|...|.|     :||.|     .:|..|||.:|.:||:..:|....|
Zfish   254 FHLLRDPTTGDLPWPGVIFG-----IAIIGSWYWCTDQVIVQRCLAARSLTHVKAGCILCGYLKL 313

  Fly   278 LPILCLLSLSTCFSGLCIYWYYRD---------CDPLLEGRVNSRDQVMPLFVVDTMGEYTGLAG 333
            ||:..::     |.|:.....|.|         |:.:....|...:...|..||..|.  |||.|
Zfish   314 LPMFLMV-----FPGMISRVLYPDDVGCVEKSVCNKVCGTEVGCSNIAYPKLVVSVMP--TGLRG 371

  Fly   334 LFVSGIFCASLSTISSIISSLAAVTLEDYLKPLVSCCAKRTLTDRQTLWYSKLLSLFFGALCIGM 398
            |.::.:..|.:|:::||.:|.:.:...|....:......:.|.....:|   :|.:...:.|...
Zfish   372 LMLAVMLAALMSSLASIFNSSSTLFTMDIWTRIRPQARDKELMVVGRVW---ILCIVGISTCWIP 433

  Fly   399 AFMAGSIGGLLQAALSIFGIIGGPLLGLFTLGMYVTKANEKGAIGGLL--ISLAFC-----FWIG 456
            ...|...|.|.....|:...:..|:..:|.|.::|.:.||.||..||:  :.:..|     |..|
Zfish   434 VVQAAQSGQLFDYIQSVTSYLAPPIAAVFFLAIFVKRVNESGAFWGLMGGLVMGLCRMVPEFVFG 498

  Fly   457 FGQPKPPLVSLDMSTAGCPVDRSFARDIFLKTVIAVAEEEHYFYLYRISYMWYAALGFLITFFGG 521
            .|....|        :.||           |.:..|    ||.|.            .::.||
Zfish   499 SGSCLKP--------SNCP-----------KVICGV----HYLYF------------AILLFF-- 526

  Fly   522 WLLSWLFALLKWDNNRRIYQDADCTLIKHDLFV----PPIA-KRLQRRQMPLLVVTGTSSEIGGI 581
                                   ||.|. .|||    |||. |.|.|     ||.|...|
Zfish   527 -----------------------CTAIL-VLFVSYNTPPIKDKHLHR-----LVFTLRHS----- 557

  Fly   582 TTESATAPPRLDEIEWEKHK 601
             ||.     |:| ::||:.:
Zfish   558 -TEE-----RVD-LDWEEEE 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32669	NP_727460.1	SLC5sbd_NIS-SMVT	7..527	CDD:271383	123/588 (21%)
slc5a2	NP_998091.1	SLC5sbd_SGLT2	15..662	CDD:212056	145/669 (22%)