Protein Alignment CG32669 and Slc5a12

DIOPT Version :10

• Sequence 1: NP_727460.1
• Gene: CG32669 / 326229
• FlyBaseID: FBgn0052669
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_001102058.1
• Gene: Slc5a12 / 362188
• RGDID: 1311652
• Length: 619
• Species: Rattus norvegicus
• Alignment Length: 550
• Identity: 220/550 - (40%)
• Similarity: 327/550 - (59%)
• Gaps: 23/550 - (4%)

  Fly     6 AWDYTILAVVLIISVAIGIYYRFVGGKQSTTTEYLLADRSMNVAPVAFSLMASFMSAVTILGVSM 70
            ||||.:.|.:.:||..||:::.....|::|:.|:|:..|.|:.||||.||.||||||||:||...
  Rat     8 AWDYVVFAALFVISSGIGVFFAIKERKKTTSREFLVGGRQMSFAPVALSLTASFMSAVTVLGTPA 72

  Fly    71 ENYQYGTMFVVINLSYVLSTPVAAYLIIPVFYRLKTASVYEYLELRFGYATRLAASLSFSLQMVL 135
            |.|::|..|::..:||.......:.|.:|||||....|.||||:|||....|.||::.:.||.:|
  Rat    73 EVYRFGASFLIFLISYAFVVFFTSELFLPVFYRSGITSTYEYLQLRFNKPVRYAATIIYILQTIL 137

  Fly   136 YMGIVVYAPALALEAVTGLSQVFSIVIVGVVCTFYATLGGMKAVLITDIYQSLLMFAAVFSVIIC 200
            |.|:|||||||||..|||.:...|:...|:|||||.:|||:|||:.||.:|.::|.....:|:|.
  Rat   138 YTGVVVYAPALALNQVTGFNLWASVFATGIVCTFYCSLGGLKAVVWTDAFQMVVMIVGFLTVLIQ 202

  Fly   201 AWVKAGSLEVIWRVAQENGRINLTNFSVDPTERHTWFTQILGGCATYLAIYGVNQTQVQRLMAVK 265
            .....|..:.:...|:...|:::.:|.|||..|||::|..:||..|:|.||||||:.:||.::.|
  Rat   203 GSNHVGGFDNVLEQARNGSRLDIVDFDVDPLRRHTFWTIAVGGTFTWLGIYGVNQSTIQRCISCK 267

  Fly   266 SLSAARAALWWCLPILCLLSLSTCFSGLCIYWYYRDCDPLLEGRVNSRDQVMPLFVVDTMGEYTG 330
            :...|:.||::.|..|.::.:...|.||.:|.||:||||...|.:.:.||:||.||::......|
  Rat   268 TEKHAKLALYFNLLGLWIIVVCAVFCGLIMYAYYKDCDPWTSGAILAPDQLMPYFVMEIFATMPG 332

  Fly   331 LAGLFVSGIFCASLSTISSIISSLAAVTLEDYLKPLVSCCAKRTLTDRQTLWYSKLLSLFFGALC 395
            |.||||:..|..:|||:::.|::||.||.||::|   ||...  |:|..:.|.||.|.|.||.:|
  Rat   333 LPGLFVACAFSGTLSTVAASINALATVTFEDFVK---SCFPH--LSDTLSTWISKGLCLLFGIIC 392

  Fly   396 IGMAFMAGSIGGLLQAALSIFGIIGGPLLGLFTLGMYVTKANEKGAIGGLLISLAFCFWIGFG-- 458
            ..||.:|..:|.::||||||.|:.|||:|||||||:.....|.|||:||||..:...||:|.|
  Rat   393 TSMAVLASLMGSVVQAALSIHGMCGGPMLGLFTLGLVFPFVNWKGALGGLLTGITLSFWVGIGAF 457

  Fly   459 ---QPKPPLVSLDMSTAGCPVDRSFARDIF-LKTVIAVAEEEHYFYLYRISYMWYAALGFLITFF 519
               .|....:.|.:||..|........:.: |.:...:|:.     .|.:||::::|:|.|....
  Rat   458 VYPAPDSKTLPLPLSTEFCVQQNKTTTEAYQLSSRPVLADT-----WYSLSYLYFSAVGCLGCIA 517

  Fly   520 GGWLLSWLFALLKWDNNRRIYQDADCTLIK 549
            .|.::|:|       ..|:..:|.|..||:
  Rat   518 AGIIISFL-------TGRQRGKDVDPLLIR 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32669	NP_727460.1	SLC5sbd_NIS-SMVT	7..527	CDD:271383	213/525 (41%)
Slc5a12	NP_001102058.1	SLC5sbd_SMCT2	3..527	CDD:212089	215/535 (40%)