DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32669 and CG31668

DIOPT Version :9

Sequence 1:	NP_727460.1	Gene:	CG32669 / 326229	FlyBaseID:	FBgn0052669	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_001097055.2	Gene:	CG31668 / 33395	FlyBaseID:	FBgn0051668	Length:	590	Species:	Drosophila melanogaster

Alignment Length:	596	Identity:	204/596 - (34%)
Similarity:	312/596 - (52%)	Gaps:	69/596 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 GAWDYTILAVVLIISVAIGIYYRFV-----GGKQSTTT-----------------EYLLADRSMN 47
            |..||.:...|.|:|:|||:|:.|:     |.|.:|.|                 :|::..|::.
  Fly     7 GTVDYAVFLGVTILSIAIGLYFGFIRKSRNGPKTTTPTNEAPERRHQNFGSKKMNDYMMGSRNLR 71

  Fly    48 VAPVAFSLMASFMSAVTILGVSMENYQYGTMFVVINLSYVLSTPVAAYLIIPVFYRLKTASVYEY 112
            |.||..||:||.:|||.|:|...|.|.|||.:..|.::.||.....:|:.:|||..|:..|.|||
  Fly    72 VFPVGMSLIASCISAVAIIGTPSEIYNYGTQYCFIVIALVLQGLAVSYIYLPVFSALQVTSSYEY 136

  Fly   113 LELRFGYATRLAASLSFSLQMVLYMGIVVYAPALALEAVTGLSQVFSIVIVGVVCTFYATLGGMK 177
            ||:||..|.|...|:.|.|.:|||:..:.|.|||||..|:|::.......:.|:|..|..|||:|
  Fly   137 LEMRFHSAIRSIVSIIFILDVVLYLPFLAYLPALALNQVSGMNMYLIEAFIIVICVIYTVLGGLK 201

  Fly   178 AVLITDIYQSLLMFAAVFSVIICAWV----KAGSLEVIWRVAQENGRINLTNFSVDPTERHTWFT 238
            ||:.|||:|.::|||:|.::::.|..    :|..||.:.|    .||:..:..:..|..|||.::
  Fly   202 AVVHTDIWQVVIMFASVLTIVVLATCYIDDQADFLEGLVR----GGRLIFSETNPSPFARHTVWS 262

  Fly   239 QILGGCATYLAIYGVNQTQVQRLMAVKSLSAARAALWWCLPILCLLSLSTCFSGLCIYWYYRDCD 303
            .::|....:.::..|:||.|.|.|::.:|..|||::.:.:..........|:.||.|:..|||||
  Fly   263 VVIGNTFYWTSLNAVHQTVVHRYMSLPTLKMARASIAFLVVGAAFFISLLCYLGLLIFHAYRDCD 327

  Fly   304 PLLEGRVNSRDQVMPLFVVDTMGEYTGLAGLFVSGIFCASLSTISSIISSLAAVTLEDYLKPLVS 368
            ||..|.:.:.||::|||||:::|...|:.|||::|||.||||::|..::|.:.|.|:|    ||.
  Fly   328 PLSAGLIMNDDQLVPLFVVNSLGHVYGMPGLFIAGIFGASLSSLSVYLNSTSLVILQD----LVR 388

  Fly   369 CCAKRTLTDRQTLWYSKLL----SLFFGALCIGMAFMAGSIGGLLQAALSIFGIIGGPLLGLFTL 429
            .|.|..|.:    |.|.::    .:..|.|...|.|:...:.|:|..::|:..|......|:||:
  Fly   389 GCFKMELGE----WASTIVVKGSIVVLGLLAFAMVFVLEKVSGVLSISVSLAAIAASSTFGIFTV 449

  Fly   430 GMYVTKANEKG-AIGGLLISLAFCFWIGFGQ----PKPPLVS--LDMSTAGCPVDRSFARDIFLK 487
            ||.|..||..| |:|| :.|:....||.||.    ....|.|  |.:|..||..:.|.|.:.:
  Fly   450 GMLVPWANTVGTAVGG-IASVLLTGWISFGSQFAAASGQLGSQRLPVSVEGCLANASVAENAW-- 511

  Fly   488 TVIAVAEEEHYFYLYRISYMWYAALGFLITFFGGWLLSWLFALLKWDNNRRIYQDADCTLIKHDL 552
                ||||| .|.|||:||.|.:.:|.|.....|.|:|            .:.:..|...:..||
  Fly   512 ----VAEEE-VFPLYRLSYHWISPIGVLTVVVVGSLVS------------LVTKPTDIKSLDSDL 559

  Fly   553 FVPPIAKRLQR 563
            ..|.|.:.|.:
  Fly   560 ITPVIHRFLPK 570

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32669	NP_727460.1	SLC5sbd_NIS-SMVT	7..527	CDD:271383	197/556 (35%)
CG31668	NP_001097055.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	192/541 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448266
Domainoid	1	1.000	233	1.000	Domainoid score	I1353
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	256	1.000	Inparanoid score	I1946
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
	10	9.900