DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32669 and Slc5a10

DIOPT Version :9

Sequence 1:	NP_727460.1	Gene:	CG32669 / 326229	FlyBaseID:	FBgn0052669	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	XP_006532041.1	Gene:	Slc5a10 / 109342	MGIID:	1926089	Length:	611	Species:	Mus musculus

Alignment Length:	554	Identity:	127/554 - (22%)
Similarity:	217/554 - (39%)	Gaps:	124/554 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LGAWDYTILAVVLIISVAIGIYYRFVGGKQSTTTEYLLADRSMNVAPVAFSLMASFMSAVTILGV 68
            |...|..:::|...::||:||:......| :|.:.|.||.|.|...|:..||.||...:...:|:
Mouse    51 LSVTDIIVISVYFALNVAVGIWSACRANK-NTVSGYFLAGRDMAWWPIGASLFASSEGSGLFVGL 114

  Fly    69 SMENYQYGTMFVVINLSYVLSTPVAAYLIIPVFYRLKTASVYEYLELRFG---YATRLAASLSFS 130
            :                   .:..|..|.:..| .....::.||::.|||   ..|.|:. ||..
Mouse   115 A-------------------GSGAAGGLAVAGF-EWNIVTLPEYIQKRFGGQRIRTYLSV-LSLM 158

  Fly   131 LQMVLYMGIVVYAPALALEAVTGLSQVFSIVIVGVVCTFYATLGGMKAVLITDIYQSLLMFAAVF 195
            |.:...:.|.:||.||.:....|.:...|.::...:...|...||:..|:.||..|:::|.....
Mouse   159 LSVFTKISIDLYAGALFVHICLGWNFYLSTILTLAITALYTIAGGLATVIYTDALQTIIMVVGAV 223

  Fly   196 SVIICAWVKAG---SLEVIWRVA------------------------QENGRINLTNFSVDPTER 233
            .:.:.|:.:.|   .||..:..|                        ...|.:..|..:...|..
Mouse   224 ILAVKAFNQIGGYEQLEAAYAQAIPSRTIPNTTCHLPRADAMHMFRDPSTGDLPWTGMTFGLTIM 288

  Fly   234 HTWFTQILGGCATYLAIYGVNQTQVQRLMAVKSLSAARAALWWCLPILCLLS--LSTCFSGLCIY 296
            .||:             :..:|..|||.::.::|:.|:|.        .:|:  |.....||.|.
Mouse   289 ATWY-------------WCTDQVIVQRSLSARNLNHAKAG--------SILASYLKMLPMGLMIM 332

  Fly   297 WYYRDCDPLLEGRVNSRDQV----------------------MPLFVVDTMGEYTGLAGLFVSGI 339
                   |.:..||...|.|                      .|..|::.|.  .||.||.::.:
Mouse   333 -------PGMISRVLFPDDVGCVVPSECLRACGAEIGCSNIAYPKLVMELMP--IGLRGLMIAVM 388

  Fly   340 FCASLSTISSIISSLAAVTLEDYLKPLVSCCAKRTLTDRQTLWYSKL-LSLFFGALCIGMAFMAG 403
            ..|.||:::||.:|.:.:...|..:.|     :.:..:|:.|...:| :.:..|.....:..:.|
Mouse   389 MAALLSSLTSIFNSSSTLFTMDIWRQL-----RPSAGERELLLVGRLVIVVLIGVSVAWIPVLQG 448

  Fly   404 SIGGLLQAAL-SIFGIIGGPLLGLFTLGMYVTKANEKGAIGGLLISL---AFCFWIGFGQPKPPL 464
            |..|.|...: |:...:..|:..:|.||::..:|||:||..||:..|   |....:.|..|:||.
Mouse   449 SNSGQLFIYMQSVTSSLAPPVTAIFILGIFWRRANEQGAFWGLMAGLVVGALRLVLEFLYPEPPC 513

  Fly   465 VSLDMSTAGCPVDRS-----FARDIFLKTVIAVA 493
            ..:|  |...|: ||     ||..:||.|...:|
Mouse   514 GQID--TRPAPL-RSLHYLHFAIALFLLTCAVMA 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32669	NP_727460.1	SLC5sbd_NIS-SMVT	7..527	CDD:271383	126/551 (23%)
Slc5a10	XP_006532041.1	SLC5-6-like_sbd	52..611	CDD:382020	126/553 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810