DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32650 and Coq8b

DIOPT Version :9

Sequence 1:	NP_727647.1	Gene:	CG32650 / 326227	FlyBaseID:	FBgn0052650	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	NP_598531.2	Gene:	Coq8b / 76889	MGIID:	1924139	Length:	533	Species:	Mus musculus

Alignment Length:	239	Identity:	57/239 - (23%)
Similarity:	82/239 - (34%)	Gaps:	79/239 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 EIGAM-NRTLDEIQAQLAIDFHERDGG------------RSCWEE--EQEALAKGLEPEDSRWMI 104
            |:||| .||...:...:.:..    ||            |||..:  .|:...:||..:|.|
Mouse     4 ELGAMLRRTCGPLGRAVRLPC----GGALGPRPHWWGPCRSCLAQSVHQDQPGRGLSEDDIR--- 61

  Fly   105 MHGSREAALRELQWNNLRIRRQLADLVRCSELGRARIS------------ALDRLFQRQTKELVG 157
              .:|||.||:..      |.||:|..|..::..:|||            .|..|.:...|.|.|
Mouse    62 --RAREARLRKAP------RPQLSDRSRERKVPASRISRLASFGGLAVGLGLGALAEVTKKSLPG 118

  Fly   158 CRQDHERVL---SFHLTKQLEAGKCLQRYRYARDLYASWRELFKMGRHL--------KEAYKKIL 211
            ....||.|.   |.....:..|.:.:|.....|.      ...|:|:.|        ....::|.
Mouse   119 GSLQHEGVSGLGSSPFLSEANAERIVQTLCTVRG------AALKIGQMLSIQDNSFISPQLQRIF 177

  Fly   212 ERTQSRLEYAEIKRQALDEMTVAHEMCLGSTRSLLARVRDLELG 255
            ||.          ||:.|.|          .|..:.||.:.|||
Mouse   178 ERV----------RQSADFM----------PRWQMMRVLEEELG 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32650	NP_727647.1	DUF4763	30..253	CDD:292582	54/235 (23%)
Coq8b	NP_598531.2	KxGQ motif. /evidence=ECO:0000250\|UniProtKB:Q8NI60	156..159		1/2 (50%)
		ABC1_ADCK3	176..425	CDD:270872	13/46 (28%)
		AAAS motif. /evidence=ECO:0000250\|UniProtKB:Q8NI60	217..220
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0661
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900