Protein Alignment Mco4 and GMC1

DIOPT Version :9

• Sequence 1: NP_573249.1
• Gene: Mco4 / 326221
• FlyBaseID: FBgn0052557
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_010794.3
• Gene: GMC1 / 852117
• SGDID: S000002914
• Length: 608
• Species: Saccharomyces cerevisiae
• Alignment Length: 573
• Identity: 128/573 - (22%)
• Similarity: 213/573 - (37%)
• Gaps: 149/573 - (26%)

  Fly   138 VMVVNGQLP--GMNIEVCYGDTVVADVIN---SMHE------------TTTIHWHGMHQRLTPFM 185
            |:.:||...  |..|.|..|||:...:.|   |..|            :|.:|:||:......|
Yeast    48 VISINGYSATFGPEIRVKSGDTLNLKLTNWICSEEEASKDSDVWKDYCSTALHFHGVVPLANEF- 111

  Fly   186 DGVPHVTQYPIEAGQAFRYRFEVDHG--GTNWWHSHTEHQRAFGLAGPLVVR------------- 235
            ||:|.:||..|..|:::.|.|.:|..  ||.|:|||:..|...|:.|.|:|.
Yeast   112 DGIPGLTQPTIGYGESYWYNFTIDQSTCGTFWYHSHSSVQYGDGMRGVLIVECDDYDNHVANTIN 176

  Fly   236 ------------MPPKLNPHA-HLYDFDMSEHVIMIQDWVHNF---------------VESVAEN 272
                        :..|.:.|. .|.|:::.|.:|.:.||..|:               .:...:.
Yeast   177 SVRDIETLDDGVVTMKKDKHTKELTDYEVQERIITLSDWYTNWNLDILNDKVLSSTGGTDPKFDG 241

  Fly   273 ILINGR---GRNLKKGVKAAKPTLYAHFPVVRGGRYRFRVIFNGVSNCPISFSIDKHDLVVIASD 334
            .||||:   |..:|.|.......|              |::.:|:|...: |.:|...|:|:.:|
Yeast   242 SLINGKSSDGETIKIGFNTEYLLL--------------RIVNSGMSGTQV-FHLDGFQLIVLEAD 291

  Fly   335 GNDIEPVEVQRIMFHGAERFDFVLHANQEVS-----NYWIRVKGYS----FCAKNQLHQEAVLHY 390
            |..|:|..||.|.....:|:..::....:.|     |...::.||.    :..|...|.:...:.
Yeast   292 GIMIKPFIVQTINLAVGQRYTILVKLKSDTSFIRMINGCNKMMGYITKQWWFYKEGAHLDLPKNP 356

  Fly   391 RDADTRALDTHTLSYAYDAPGKTLNELGDDASGARAGNSISLANLNAQRPEPEVAPSVTFYTSMN 455
            .|.....|           ||.|..||..|....:..|         ::...:..|...|
Yeast   357 NDVSIEHL-----------PGFTKAELYRDIEPTQEEN---------KKLRTKADPVAVF----- 396

  Fly   456 AFEVRQGEGFRFQMDDISFSMPKMSLLQTRNLGVGQFFCNRSQQADLGFNCRQRHCQCSNVIQVP 520
            .|:      :.:..|:.:          .:..|.|.:..|....::          ...:.::..
Yeast   397 EFD------YAYYKDEST----------KQKYGTGMYKVNERTFSE----------YVKDPVRFG 435

  Fly   521 ANQQVEFVISSLSQTPHPIHLHGYTFRVVGMGVLG---------EQKIGQIEQIDKKTPLPRRAK 576
            .|:..:.||:||....||.|:||:.|:::.:|..|         |.|.....|.|.: .|.|..|
Yeast   436 FNETYDIVINSLDHMRHPWHMHGHHFQIISLGNKGDGPFHKDVQEGKAWSRYQNDLR-HLARTGK 499

  Fly   577 GAPLKDSVQVPAFGYTILRFYSNSPGYWMFHCHISPHSENGMAAVVRVGEDVE 629
            ...::||:.:....|.:||..:..||.|:.|||:..|...|:..|..|....|
Yeast   500 APMVRDSINIAGNSYAVLRINTEMPGKWLLHCHVEWHMMKGLGIVFEVPTTTE 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mco4	NP_573249.1	ascorbase	132..626	CDD:274555	127/568 (22%)
		CuRO_1_tcLCC2_insect_like	132..235	CDD:259927	37/115 (32%)
		CuRO_2_tcLCC_insect_like	253..390	CDD:259951	34/163 (21%)
		CuRO_3_tcLLC2_insect_like	468..633	CDD:259972	40/171 (23%)
GMC1	NP_010794.3	SufI	24..547	CDD:225043	126/566 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343592
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2132
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S12213
OMA	1	1.010	-	-		QHG58299
OrthoFinder	1	1.000	-	-		FOG0000424
OrthoInspector	1	1.000	-	-		mtm9215
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11709
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.800