Protein Alignment Mco4 and cp

DIOPT Version :10

• Sequence 1: NP_573249.1
• Gene: Mco4 / 326221
• FlyBaseID: FBgn0052557
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_571877.1
• Gene: cp / 84702
• ZFINID: ZDB-GENE-010522-1
• Length: 1087
• Species: Danio rerio
• Alignment Length: 762
• Identity: 149/762 - (19%)
• Similarity: 238/762 - (31%)
• Gaps: 316/762 - (41%)

  Fly    17 SVQIYGIQ---DASGK---------------RIVSKYERIMQMYP--QLSSGAGESSQWRAAEKD 61
            |:|.:|:|   |..|.               |.:.|..|:::..|  .:........:| ...||
Zfish   475 SIQPHGVQYNIDMDGTLYHNVLEESYTDKKLRELKKQPRVIEPLPAAMVRPDTTYKYEW-VVPKD 538

  Fly    62 ---NQRHPCRRDCADKQPMTCYYYMVVHYDDTMAET----------CKRYLQSKFRFKLSGKEYI 113
               .::.|   ||     :|..||..|   |.:.:|          ||.......:.|...||:
Zfish   539 GGPTEKDP---DC-----LTYLYYSAV---DPIRDTNSGLVGPLLICKPKTLKSGKQKNVDKEF- 591

  Fly   114 DGIALATQLAAN-----DD--CKY-----------ADGLESEVM-----VVNGQLPGMNIEVCYG 155
              ..|||....|     ||  .:|           ||..||..|     .:.|.|.|:|  :|.|
Zfish   592 --HLLATVFDENLSWYLDDNINRYAKQPKSVNKEDADFQESNKMHSLNGYMYGNLKGLN--MCKG 652

  Fly   156 DTVVADVINSMHETTTIHWHGMHQRLTPFM------DGV---PHVT----QYPIEAGQAFRYRFE 207
            |.|...:.....||..   ||::.....|:      |.:   ||::    ..|...||     ||
Zfish   653 DKVSWHLSGLGSETDI---HGLYFEGNRFLYKETRRDTINVFPHISHTVIMEPDSMGQ-----FE 709

  Fly   208 VD-------HGG---------TNWWHSHTE---HQRAFGLAGPLVVRMPPKLNPHAHLYDFDMSE 253
            |:       |||         ..:|:..:|   ||:.:.:|   .|.|           |:|.|.
Zfish   710 VNCKTTDHYHGGMRANYTVEKCRFWNRQSETMLHQKKYYIA---AVEM-----------DWDYSP 760

  Fly   254 HVIMIQDWVHNFVESVAENILINGRGRNLKKGVKAAKPTLYAHF--------------------- 297
             ....:|.:||.::....|..:...|:.:  |.| .|..||..:
Zfish   761 -TRTWEDKMHNGLKESPGNEFLKKEGKFI--GSK-YKKVLYKEYTDETFTKLKERTADMEHLGIM 821

  Fly   298 -PVVRG--GRYRFRVIFNGVSNCPISFSIDKHDLVVIASDGNDI---EPVEVQRIMFHGAERFDF 356
             |::.|  |. :.:::|..::..|  :||..|.   :.:|...:   .|.|.|        .:.:
Zfish   822 GPMIHGKVGE-KVKIVFKNMARRP--YSIHAHG---VKTDSPQVPLTRPGETQ--------TYTW 872

  Fly   357 VLHAN------QE---VSNYWIRV----KGYS-------FCAKN---------QLHQEAVLH--Y 390
            .|..|      ||   |..|:..|    ..||       .|.|:         ::.:.|:|.  :
Zfish   873 YLPKNSGPTEEQEECSVGAYYSTVDVIKDMYSGLVGPLVICKKSLARTLGLKKEVEEFALLFMVF 937

  Fly   391 RDADTRALDTHTLSYAYDAPGKTLNELGD----DASGARAGNSISLANLNAQRPEPEVAPSVTFY 451
            .:.::..|:.:..::..:.| |.|.|  |    :::.....|.:...||...  ..:|...|.:|
Zfish   938 DENESWYLEENIKTHVKNPP-KALTE--DQQFIESNKMHGINGLVFGNLKGL--NMKVGDKVYWY 997

  Fly   452 TSMNAFEVRQGEGFRFQMDDISFSMPKMSLLQTRNLGVGQFFCNRSQQADLGFNCRQRHCQCSNV 516
            .                                  :|:|                        |.
Zfish   998 L----------------------------------MGLG------------------------NE 1004

  Fly   517 IQVPANQQVEFVISSLSQTPHPIHLHGYTFRVVGMGVLGEQKIGQIEQIDKKTPLPRRAKGAPLK 581
            :.:                 |..|.||::|                   |.|.....||....|
Zfish  1005 VDI-----------------HTAHFHGHSF-------------------DYKVSGTHRADVFDL- 1032

  Fly   582 DSVQVPAFGYTILR--FYSNSPGYWMFHCHISPHSENGMAAVVRVGE 626
                ||....|:..  .||   |.|:.|||::.|.:.||.....|.|
Zfish  1033 ----VPGTFQTVTMRPLYS---GTWLLHCHVTDHIQAGMETTYTVLE 1072

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mco4	NP_573249.1	SufI	131..624	CDD:441735	113/593 (19%)
cp	NP_571877.1	CuRO_1_ceruloplasmin	23..205	CDD:259884
		CuRO_2_ceruloplasmin	217..357	CDD:259907
		Cupredoxin	371..585	CDD:473140	24/121 (20%)
		CuRO_4_ceruloplasmin	588..731	CDD:259908	39/155 (25%)
		CuRO_5_ceruloplasmin	745..915	CDD:259887	38/201 (19%)
		CuRO_6_ceruloplasmin	927..1071	CDD:259898	40/250 (16%)