DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mco4 and sks3

DIOPT Version :9

Sequence 1:	NP_573249.1	Gene:	Mco4 / 326221	FlyBaseID:	FBgn0052557	Length:	645	Species:	Drosophila melanogaster
Sequence 2:	NP_199656.2	Gene:	sks3 / 834900	AraportID:	AT5G48450	Length:	621	Species:	Arabidopsis thaliana

Alignment Length:	514	Identity:	126/514 - (24%)
Similarity:	205/514 - (39%)	Gaps:	98/514 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 GLESEVMVVNGQLPGMNIEVCYGDTVVADVINSMHETTTIHWHGMHQRLTPFMDGVPHVTQYPIE 197
            |...:|:.:|||.||..:.|.....||.:|.|::.|...:.|:|:..|...:.|||.. |..||.
plant    44 GTRQQVIGINGQFPGPILNVTTNWNVVMNVKNNLDEPLLLTWNGIQHRKNSWQDGVLG-TNCPIP 107

  Fly   198 AGQAFRYRFEV-DHGGTNWWHSHTEHQRAFGLAGPLVVRMPPKLNPHAHLYDFDMSEHVIMIQDW 261
            :|..:.|.|:| |..|:.::...|..|||.|..|.::|.....:.....|.|.|::   :.|.||
plant   108 SGWNWTYEFQVKDQIGSFFYFPSTNFQRASGGYGGIIVNNRAIIPVPFALPDGDVT---LFISDW 169

  Fly   262 -------VHNFVES-----VAENILINGRGRNLKKGVKAAKPTLYAHFPVVRGGRYRFRVIFNGV 314
                   :...|||     ..:.|:|||.|.....|      :.:....|..|..|||||..:|:
plant   170 YTKSHKKLRKDVESKNGLRPPDGIVINGFGPFASNG------SPFGTINVEPGRTYRFRVHNSGI 228

  Fly   315 SNCPISFSIDKHDLVVIASDGNDIEPVEVQRIMFHGAERFDFVLHANQEVSNYWIRVKGYSFCAK 379
            :. .::|.|..|:|:::.::|:.........:..|..:.|.|::..:|..||.:..|....|...
plant   229 AT-SLNFRIQNHNLLLVETEGSYTIQQNYTNMDIHVGQSFSFLVTMDQSGSNDYYIVASPRFATS 292

  Fly   380 NQLHQEAVLHYRDADTRA----------LDTHTLSYAYDAPGKTLNELGDDASGARAGNSISLAN 434
            .:....|||.|.::...|          |||..          ::|:          ..|:.| |
plant   293 IKASGVAVLRYSNSQGPASGPLPDPPIELDTFF----------SMNQ----------ARSLRL-N 336

  Fly   435 LN--AQRPEPEVAPSVTFYTSMNAF-------EVRQGEGFRFQMDDISFSMP--KMSLLQTRNL- 487
            |:  |.||.|:.:......|..:.:       |:.:|. .|..::.||:..|  .:.|.|..|:
plant   337 LSSGAARPNPQGSFKYGQITVTDVYVIVNRPPEMIEGR-LRATLNGISYLPPATPLKLAQQYNIS 400

  Fly   488 GVGQFF-----CNRSQQADLGFNCRQRHCQCSNVIQVPANQQVEFVISSLSQTPHPIHLHGYTFR 547
            ||.:..     .||..:.|            ::||.......||.:..:...|....||.||.|.
plant   401 GVYKLDFPKRPMNRHPRVD------------TSVINGTFKGFVEIIFQNSDTTVKSYHLDGYAFF 453

  Fly   548 VVGM--GVLGEQKIGQIEQIDKKTPLPRRAKGAPLKDSVQVPAFGYTILRFYSNSPGYW 604
            ||||  |:..|.......:.|           |..:.:.||....:|.:....::.|.|
plant   454 VVGMDFGLWTENSRSTYNKGD-----------AVARSTTQVFPGAWTAVLVSLDNAGMW 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mco4	NP_573249.1	ascorbase	132..626	CDD:274555	126/514 (25%)
		CuRO_1_tcLCC2_insect_like	132..235	CDD:259927	34/102 (33%)
		CuRO_2_tcLCC_insect_like	253..390	CDD:259951	36/148 (24%)
		CuRO_3_tcLLC2_insect_like	468..633	CDD:259972	34/147 (23%)
sks3	NP_199656.2	PLN00044	17..559	CDD:165622	126/514 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2132
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D454773at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11709
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.880