Protein Alignment Mco4 and F21D5.3

DIOPT Version :10

• Sequence 1: NP_573249.1
• Gene: Mco4 / 326221
• FlyBaseID: FBgn0052557
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_001255321.1
• Gene: F21D5.3 / 177680
• WormBaseID: WBGene00009008
• Length: 743
• Species: Caenorhabditis elegans
• Alignment Length: 641
• Identity: 145/641 - (22%)
• Similarity: 241/641 - (37%)
• Gaps: 164/641 - (25%)

  Fly   126 DDCKYADGLESEVMVVNGQLPGMNIEVCYGDTVVADVINS-MHETTTIHWHGMHQRLTPFMDGVP 189
            :|....|||...|:.:||.:||..:.|.|...|...|.|. :.::.|||.||:.:....:||||.
 Worm   104 EDVLVVDGLHKRVISINGDMPGAPVVVPYMSEVWIRVSNQILMDSMTIHVHGIDKHGMWYMDGVA 168

  Fly   190 HVTQYPIEAGQAFRYRFEVDHGGTNWWHSHTEHQRAFGLAGPLVV-----RMPPKLNPHAHLYDF 249
            .|.|.||::...|.|||..|:.||:|:|.|.:..|..|:||..:|     ...|.|:....:  .
 Worm   169 FVQQCPIQSTNKFEYRFIADNKGTHWYHGHMQTDRGDGIAGGFIVVDQNDTSVPTLDDRKRI--V 231

  Fly   250 DMSEHVIMIQDWVHNFVESV--------------------------------------AENILIN 276
            ...|:..::|||.....|..                                      ...||:|
 Worm   232 PSREYFFLLQDWATKVGEEAWMQLEDKTMKWMYGYDDFTKCWEPTRTSDGGNVGGAVPISAILLN 296

  Fly   277 GRGRNLKKGVKAAKPTL-YAHFPVVRGGRYRFRVIFNGVSNCPISFSIDKHDLVVIASDGNDIEP 340
            .:|......:|:....| ...|.:.......||::..||:. .:...::.|.:.|:|:||:::.|
 Worm   297 DKGWYDHDIIKSQPFNLPLERFQIKPNEDILFRIVNGGVAQ-ELMLYVEGHPMTVVAADGDEVVP 360

  Fly   341 VEVQRIMFHGAERFDFVLH--ANQEVSNYWIRVK----------------GYSF----------- 376
            ::|.|::....||:|.::.  |.....:|.|:|:                |:.:
 Worm   361 MKVDRLIVFPGERYDILIKGLATPTKKSYRIQVETVQKYFFDWKEIPIVYGFGYIEYETDGLPED 425

  Fly   377 -CAKNQLHQE-------AVLHYRDADTRALDTHTLSYAYDAPGKTLNELGDDASGARAGNSISLA 433
             ...|.:|.|       .||:....:..|....| ..:||                      .|.
 Worm   426 KTTPNLMHPECTQNKKCTVLNCPFQEWMAQPNFT-CISYD----------------------KLE 467

  Fly   434 NLNAQRPEPEVAPSVTFYTSMNAFEVRQGEGF-----RFQMDDISFSMP------KMSLLQTRNL 487
            |.|.::.|.|:..:..|   ...||    |.|     ..|||...|..|      ....::|.:.
 Worm   468 NPNPEKIEAEILQATQF---NGGFE----EHFINMHHDSQMDQFLFQFPWGIPYYHDGDMETIST 525

  Fly   488 GVGQFFCNRSQQADLGFNCRQRHCQCSNVIQVPANQQVEFVISSL-------SQTPHPIHLHGYT 545
            ...|..|..:..:||...||     |...::...|..|:..:.::       :...||.||||:.
 Worm   526 SCSQTACANNSMSDLDTTCR-----CFYHLEHKLNNIVQITLYNMGLGGAMGTGYAHPFHLHGHH 585

  Fly   546 FRVVGMGVLGEQKIGQIEQIDKKTPLPRR-----------------------AKGAPLKDSVQVP 587
            |.|:.:|.......|.|:|:::....|.|                       .|....:|::.:|
 Worm   586 FYVMKVGWPSYNGSGFIDQMNQDIDCPGRDVSCNGKKWRNKDWLGGALEAMNTKNPTKRDTITLP 650

  Fly   588 AFGYTILRFYSNSPGYWMFHCHISPHSENGMAAVVRVGEDVEMKMCPVS---NCGL 640
            ..||..:||.:.:||:|..|||:..|...|.....:||:..::.|.|.:   :||:
 Worm   651 VGGYITIRFRAVNPGWWFAHCHLELHLMGGTGYAYKVGDQNQIYMPPDNFPHDCGV 706

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mco4	NP_573249.1	SufI	131..624	CDD:441735	138/615 (22%)
F21D5.3	NP_001255321.1	CuRO_1_tcLCC2_insect_like	110..213	CDD:259927	40/102 (39%)
		PLN02191	116..708	CDD:177843	141/629 (22%)
		CuRO_3_tcLLC2_insect_like	500..696	CDD:259972	46/200 (23%)