Protein Alignment Mco4 and F21D5.3

DIOPT Version :9

• Sequence 1: NP_573249.1
• Gene: Mco4 / 326221
• FlyBaseID: FBgn0052557
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_001255321.1
• Gene: F21D5.3 / 177680
• WormBaseID: WBGene00009008
• Length: 743
• Species: Caenorhabditis elegans
• Alignment Length: 641
• Identity: 145/641 - (22%)
• Similarity: 241/641 - (37%)
• Gaps: 164/641 - (25%)

  Fly   126 DDCKYADGLESEVMVVNGQLPGMNIEVCYGDTVVADVINS-MHETTTIHWHGMHQRLTPFMDGVP 189
            :|....|||...|:.:||.:||..:.|.|...|...|.|. :.::.|||.||:.:....:||||.
 Worm   104 EDVLVVDGLHKRVISINGDMPGAPVVVPYMSEVWIRVSNQILMDSMTIHVHGIDKHGMWYMDGVA 168

  Fly   190 HVTQYPIEAGQAFRYRFEVDHGGTNWWHSHTEHQRAFGLAGPLVV-----RMPPKLNPHAHLYDF 249
            .|.|.||::...|.|||..|:.||:|:|.|.:..|..|:||..:|     ...|.|:....:  .
 Worm   169 FVQQCPIQSTNKFEYRFIADNKGTHWYHGHMQTDRGDGIAGGFIVVDQNDTSVPTLDDRKRI--V 231

  Fly   250 DMSEHVIMIQDWVHNFVESV--------------------------------------AENILIN 276
            ...|:..::|||.....|..                                      ...||:|
 Worm   232 PSREYFFLLQDWATKVGEEAWMQLEDKTMKWMYGYDDFTKCWEPTRTSDGGNVGGAVPISAILLN 296

  Fly   277 GRGRNLKKGVKAAKPTL-YAHFPVVRGGRYRFRVIFNGVSNCPISFSIDKHDLVVIASDGNDIEP 340
            .:|......:|:....| ...|.:.......||::..||:. .:...::.|.:.|:|:||:::.|
 Worm   297 DKGWYDHDIIKSQPFNLPLERFQIKPNEDILFRIVNGGVAQ-ELMLYVEGHPMTVVAADGDEVVP 360

  Fly   341 VEVQRIMFHGAERFDFVLH--ANQEVSNYWIRVK----------------GYSF----------- 376
            ::|.|::....||:|.::.  |.....:|.|:|:                |:.:
 Worm   361 MKVDRLIVFPGERYDILIKGLATPTKKSYRIQVETVQKYFFDWKEIPIVYGFGYIEYETDGLPED 425

  Fly   377 -CAKNQLHQE-------AVLHYRDADTRALDTHTLSYAYDAPGKTLNELGDDASGARAGNSISLA 433
             ...|.:|.|       .||:....:..|....| ..:||                      .|.
 Worm   426 KTTPNLMHPECTQNKKCTVLNCPFQEWMAQPNFT-CISYD----------------------KLE 467

  Fly   434 NLNAQRPEPEVAPSVTFYTSMNAFEVRQGEGF-----RFQMDDISFSMP------KMSLLQTRNL 487
            |.|.::.|.|:..:..|   ...||    |.|     ..|||...|..|      ....::|.:.
 Worm   468 NPNPEKIEAEILQATQF---NGGFE----EHFINMHHDSQMDQFLFQFPWGIPYYHDGDMETIST 525

  Fly   488 GVGQFFCNRSQQADLGFNCRQRHCQCSNVIQVPANQQVEFVISSL-------SQTPHPIHLHGYT 545
            ...|..|..:..:||...||     |...::...|..|:..:.::       :...||.||||:.
 Worm   526 SCSQTACANNSMSDLDTTCR-----CFYHLEHKLNNIVQITLYNMGLGGAMGTGYAHPFHLHGHH 585

  Fly   546 FRVVGMGVLGEQKIGQIEQIDKKTPLPRR-----------------------AKGAPLKDSVQVP 587
            |.|:.:|.......|.|:|:::....|.|                       .|....:|::.:|
 Worm   586 FYVMKVGWPSYNGSGFIDQMNQDIDCPGRDVSCNGKKWRNKDWLGGALEAMNTKNPTKRDTITLP 650

  Fly   588 AFGYTILRFYSNSPGYWMFHCHISPHSENGMAAVVRVGEDVEMKMCPVS---NCGL 640
            ..||..:||.:.:||:|..|||:..|...|.....:||:..::.|.|.:   :||:
 Worm   651 VGGYITIRFRAVNPGWWFAHCHLELHLMGGTGYAYKVGDQNQIYMPPDNFPHDCGV 706

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mco4	NP_573249.1	ascorbase	132..626	CDD:274555	139/616 (23%)
		CuRO_1_tcLCC2_insect_like	132..235	CDD:259927	41/108 (38%)
		CuRO_2_tcLCC_insect_like	253..390	CDD:259951	37/212 (17%)
		CuRO_3_tcLLC2_insect_like	468..633	CDD:259972	46/200 (23%)
F21D5.3	NP_001255321.1	CuRO_1_tcLCC2_insect_like	110..213	CDD:259927	40/102 (39%)
		PLN02191	116..708	CDD:177843	141/629 (22%)
		CuRO_3_tcLLC2_insect_like	500..696	CDD:259972	46/200 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167260
Domainoid	1	1.000	87	1.000	Domainoid score	I5086
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	210	1.000	Inparanoid score	I2375
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58299
OrthoDB	1	1.010	-	-		D454773at2759
OrthoFinder	1	1.000	-	-		FOG0000424
OrthoInspector	1	1.000	-	-		otm14491
orthoMCL	1	0.900	-	-		OOG6_100257
Panther	1	1.100	-	-	LDO	PTHR11709
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X253
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.910