DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32488 and CG32487

DIOPT Version :9

Sequence 1:	NP_001286926.1	Gene:	CG32488 / 326220	FlyBaseID:	FBgn0052488	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_728791.1	Gene:	CG32487 / 38358	FlyBaseID:	FBgn0052487	Length:	320	Species:	Drosophila melanogaster

Alignment Length:	302	Identity:	120/302 - (39%)
Similarity:	181/302 - (59%)	Gaps:	12/302 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LPKQRVRQWLSTFESVILDADGVLWHFSKAIDGAVDTFNYMNTTGRKIFIISNNSEISRQEMADK 76
            |.|..::|||.|.:::|.|.:||||...|.::.|.:|||.:...|:|.||.:|||..|.:.:...
  Fly    19 LNKYGIQQWLKTIDTIIFDGNGVLWSHGKVLENAAETFNALRAMGKKAFICTNNSVTSVEGICKY 83

  Fly    77 AKGFGIEIKEDNVLTSSFSCANFLAVKNFQKKVFVMGEKGVHFELEKFGICSLKMS----EKLEK 137
            |:..|..:.::.:|:|..:.|.|:..|.|:||.:|:|.:|:..||:..||.||.:.    :....
  Fly    84 AQEMGFLVAKNEILSSVQTLAKFMKEKKFKKKCYVVGGQGIVDELKLVGIESLPLDHSSLQGFSM 148

  Fly   138 PMHEFVTELELDPDVGAVIVGRDEGFNMAKLVRTGSYLLNPDVIFLGTCLDAAYPIGNNRVMVGA 202
            |.|  :..:.|||:||||:||.|:.||..||.:...||.:.:|:|:.|..|||.|....|::..|
  Fly   149 PDH--IHSIYLDPNVGAVVVGSDKDFNTIKLTKACCYLRDSEVMFVATSRDAALPAAPGRMVPSA 211

  Fly   203 GATLAAMKAYTGRSPLVLGKPNPWMASTLMQSGAIKPETTLMVGDTLQTDMHFASNCGFQSLMVG 267
            |..:||::|.:.|.|...|||||:|...|||.|.|:|:.||::|||:.||:.....||||:|:||
  Fly   212 GVMVAAIQAASQRMPFTCGKPNPYMCIDLMQKGVIQPDRTLIIGDTMCTDILLGYKCGFQTLLVG 276

  Fly   268 SGVNTPKEVQQIIEEGDPKKKIL---VPDTYLPSLGHMLEFL 306
            :|||:   .|..||....|..:|   |||.|:|.|.::|.||
  Fly   277 TGVNS---YQDAIEAQGSKAPLLYQQVPDLYMPKLSNLLPFL 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32488	NP_001286926.1	PGP_euk	23..300	CDD:273635	111/283 (39%)
		Hydrolase_6	27..127	CDD:290083	35/99 (35%)
		Hydrolase_like	219..285	CDD:289983	32/65 (49%)
CG32487	NP_728791.1	PGP_euk	30..311	CDD:273635	112/285 (39%)
		Hydrolase_6	34..134	CDD:290083	35/99 (35%)
		Hydrolase_like	229..>281	CDD:289983	28/51 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469117
Domainoid	1	1.000	66	1.000	Domainoid score	I6520
eggNOG	1	0.900	-	-		E1_COG0647
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1438
Isobase	1	0.950	-	0	Normalized mean entropy	S1709
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D337140at33208
OrthoFinder	1	1.000	-	-		FOG0000783
OrthoInspector	1	1.000	-	-		mtm8827
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19288
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X675
	10	9.940