DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32488 and pho2

DIOPT Version :9

Sequence 1:	NP_001286926.1	Gene:	CG32488 / 326220	FlyBaseID:	FBgn0052488	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_596255.1	Gene:	pho2 / 2539960	PomBaseID:	SPBC15D4.15	Length:	298	Species:	Schizosaccharomyces pombe

Alignment Length:	300	Identity:	102/300 - (34%)
Similarity:	158/300 - (52%)	Gaps:	19/300 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PKQRVRQWLSTFESVILDADGVLWHFSKAIDGAVDTFNYMNTTGRKIFIISNNSEISRQEMADKA 77
            ||: .::::..|:..:.|.|||||..||.|.|..||...:.:.|::|..:||||..||:...:|.
pombe     8 PKE-YKEFIDKFDVFLFDCDGVLWSGSKPIPGVTDTMKLLRSLGKQIIFVSNNSTKSRETYMNKI 71

  Fly    78 KGFGIEIKEDNVLTSSFSCANFLAVKNF-----QKKVFVMGEKGVHFELEKFGICSLKMSE-KLE 136
            ...||..|.:.:..|::|.|.:  ||..     .|||||:||.|:..||::.|:..:..:: .|.
pombe    72 NEHGIAAKLEEIYPSAYSSATY--VKKVLKLPADKKVFVLGEAGIEDELDRVGVAHIGGTDPSLR 134

  Fly   137 KPM-HEFVTELELDPDVGAVIVGRDEGFNMAKLVRTGSYLLNPDVIFLGTCLDAAYPIGNNRVMV 200
            :.: .|.|.::..||.||||:.|.|......|......||.:|:..||.|..|:.:|. |.:.:.
pombe   135 RALASEDVEKIGPDPSVGAVLCGMDMHVTYLKYCMAFQYLQDPNCAFLLTNQDSTFPT-NGKFLP 198

  Fly   201 GAGATLAAMKAYTGRSPLVLGKPNPWMASTLMQSGAIKPETTLMVGDTLQTDMHFASNCGF-QSL 264
            |:||....:...|||.|.:||||...|...::.:.....:....|||.|.||:.||.|... .||
pombe   199 GSGAISYPLIFSTGRQPKILGKPYDEMMEAIIANVNFDRKKACFVGDRLNTDIQFAKNSNLGGSL 263

  Fly   265 MVGSGVNTPKEVQQIIEEGDPKKKILVPDTYLPSLGHMLE 304
            :|.:||:  || ::|:|:..|    :|||.|:.||..:.|
pombe   264 LVLTGVS--KE-EEILEKDAP----VVPDYYVESLAKLAE 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32488	NP_001286926.1	PGP_euk	23..300	CDD:273635	98/284 (35%)
		Hydrolase_6	27..127	CDD:290083	40/104 (38%)
		Hydrolase_like	219..285	CDD:289983	23/66 (35%)
pho2	NP_596255.1	NagD	11..298	CDD:223720	99/295 (34%)
		Hydrolase_6	21..123	CDD:290083	39/103 (38%)
		Hydrolase_like	217..294	CDD:289983	30/83 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	78	1.000	Domainoid score	I2380
eggNOG	1	0.900	-	-		E1_COG0647
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	169	1.000	Inparanoid score	I1198
OMA	1	1.010	-	-		QHG60740
OrthoFinder	1	1.000	-	-		FOG0000783
OrthoInspector	1	1.000	-	-		otm47201
orthoMCL	1	0.900	-	-		OOG6_100677
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R944
SonicParanoid	1	1.000	-	-		X675
TreeFam	1	0.960	-	-
	11	10.850