DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32488 and K02D10.1

DIOPT Version :9

Sequence 1:	NP_001286926.1	Gene:	CG32488 / 326220	FlyBaseID:	FBgn0052488	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_498939.3	Gene:	K02D10.1 / 176232	WormBaseID:	WBGene00019301	Length:	526	Species:	Caenorhabditis elegans

Alignment Length:	281	Identity:	82/281 - (29%)
Similarity:	147/281 - (52%)	Gaps:	24/281 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LSTFESVILDADGVLWHFSKAIDGAVDTFN-YMNTTGRKIFIISNNSEISRQEMADKAK--GFGI 82
            |:.:::.:.|||||||.....:.||::..| .:....:|:|:::|||..:.::...|.:  |||
Worm    12 LANYDTFLFDADGVLWTGDIPVPGAIEWINLLLEDPSKKVFVLTNNSTKTLEQYMKKIEKLGFG- 75

  Fly    83 EIKEDNVLTSSFSCANFL---AVKNFQKKVFVMGEKGVHFELEK------FGICSLKMSEKLEKP 138
            .:..:||::.:...|::|   |.|...:.|:::|.:.:...||.      ||.....:.:..:
Worm    76 HLGRNNVISPAIVLADYLKSNADKFSGEYVYLIGTENLKATLENDGGVKCFGTGPDSIRDHTD-- 138

  Fly   139 MHEFVTELELDPDVGAVIVGRDEGFNMAKLVRTGSYLLNPDVIFLGTCLDAAYPIGNNRVMV-GA 202
             .:|:.::::.....||:...|..|:..|:::..:||.:|.|.:|.|..|..:|.....|:: |:
Worm   139 -GDFIHKVDMSIAPKAVVCSYDAHFSYPKIMKASNYLQDPSVEYLVTNQDYTFPGPVPGVVIPGS 202

  Fly   203 GATLAAMKAYTGRSPLVLGKPNPWMASTLMQSGAIKPETTLMVGDTLQTDMHFASNCGFQSLMVG 267
            |||.||:.|.|||.|.|.|||:..||..|::...:.|:.|:|.||.|.||:.|.:..|..|.
Worm   203 GATSAAVTAVTGRDPKVFGKPHKPMADFLLRRAHVDPKRTVMFGDRLDTDIMFGNANGQLSA--- 264

  Fly   268 SGVNTPKEVQQIIEEGDPKKK 288
                ||.:.|...|..:|:|:
Worm   265 ----TPIQCQNESENSEPQKQ 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32488	NP_001286926.1	PGP_euk	23..300	CDD:273635	81/279 (29%)
		Hydrolase_6	27..127	CDD:290083	31/111 (28%)
		Hydrolase_like	219..285	CDD:289983	22/65 (34%)
K02D10.1	NP_498939.3	HAD-SF-IIA	18..264	CDD:273637	74/249 (30%)
		Hydrolase_6	18..121	CDD:290083	29/103 (28%)
		Hydrolase_like	219..>260	CDD:289983	16/40 (40%)
		NIPSNAP	427..524	CDD:285252
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I8019
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D337140at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R944
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.040