DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32488 and pgp

DIOPT Version :9

Sequence 1:	NP_001286926.1	Gene:	CG32488 / 326220	FlyBaseID:	FBgn0052488	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001363850.1	Gene:	pgp / 100488448	XenbaseID:	XB-GENE-999283	Length:	306	Species:	Xenopus tropicalis

Alignment Length:	298	Identity:	85/298 - (28%)
Similarity:	155/298 - (52%)	Gaps:	4/298 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 TKLPKQRVRQWLSTFESVILDADGVLWHFSKAIDGAVDTFNYMNTTGRKIFIISNNSEISRQEMA 74
            ::|..:..|::|::.::|:.|.|||||...:||.||.|..|.:....:::|.::|||..:|...|
Frog     7 SRLNGELSRRFLASVDTVLFDCDGVLWRGDEAIPGAPDLINGLKRANKRVFFLTNNSTKTRSMYA 71

  Fly    75 DKAKGFGIEIKEDNVLTSSFSCANFLA-VKNFQKKVFVMGEKGVHFELEKFGICSLKMSEKLEKP 138
            :|....|.:.:.:.|..:::..|.:|. :...:.||:::|.:.:..|....||..|.........
Frog    72 EKLGRLGFKAEPEEVFGTAYCTAIYLRDIARLKGKVYLIGGRALSEEFGAAGIPHLGCGADHVTG 136

  Fly   139 MHEFVTELELDPDVGAVIVGRDEGFNMAKLVRTGSYLLNPDVIFLGTCLDAAYPIGNNRVMVGAG 203
            ..:....::.|.||.||:||.||.|:..||.|...||.:|..:|:.|..|...|:...|.:.|.|
Frog   137 TQKDWASVQGDSDVKAVVVGFDEHFSYMKLNRALQYLQDPSCLFIATNTDTRLPLEGGRAIPGTG 201

  Fly   204 ATLAAMKAYTGRSPLVLGKPNPWMASTLMQSGAIKPETTLMVGDTLQTDMHFASNCGFQSLMVGS 268
            ..:.|::....|...|:|||:.::...:::...:.|..|:||||.|.||:...|.||.::|:..:
Frog   202 CLVRAVETAAHRKAQVIGKPSSFLYDCVVKDCGLDPARTVMVGDRLDTDIQMGSTCGIRTLLTLT 266

  Fly   269 GVNTPKEVQQIIEEGDPKKKILVPDTYLPSLGHMLEFL 306
            |.::.::.:...:.|   ...:|||.|:.|:..:|..|
Frog   267 GFSSLEDAKSYQDSG---ALSMVPDYYVNSVADLLPAL 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32488	NP_001286926.1	PGP_euk	23..300	CDD:273635	80/277 (29%)
		Hydrolase_6	27..127	CDD:290083	29/100 (29%)
		Hydrolase_like	219..285	CDD:289983	19/65 (29%)
pgp	NP_001363850.1	HAD_like	21..301	CDD:389748	81/282 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	59	1.000	Domainoid score	I10473
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60740
OrthoDB	1	1.010	-	-		D337140at33208
OrthoFinder	1	1.000	-	-		FOG0000783
OrthoInspector	1	1.000	-	-		otm48314
Panther	1	1.100	-	-	O	PTHR19288
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R944
SonicParanoid	1	1.000	-	-		X675
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.150