Protein Alignment Sk2 and Sk1

DIOPT Version :9

• Sequence 1: NP_647762.3
• Gene: Sk2 / 326219
• FlyBaseID: FBgn0052484
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: NP_572717.1
• Gene: Sk1 / 32089
• FlyBaseID: FBgn0030300
• Length: 641
• Species: Drosophila melanogaster
• Alignment Length: 683
• Identity: 283/683 - (41%)
• Similarity: 401/683 - (58%)
• Gaps: 95/683 - (13%)

  Fly     7 KTTSPSSASSRATPPGTQDADEG--HDVSDTFYT-SQRKKGSHVFRVRLDATGFTLQRESPGGSI 68
            ||..||      ||....:...|  .::|:.|:. :.|:|.|...:|:|...|..|:||:.....
  Fly    18 KTHEPS------TPTSDTEVASGTPTELSEIFFVDNSRRKQSIKIQVKLCPEGVYLRRETEEDDH 76

  Fly    69 VKEQHVRISDIVGARCMRPKKSRRLAMSGACACSSGNPNSPAISASGDHHRPATTPSKCSTNSRD 133
            :.||.:||.||:|:|..|..|.|  |..|..:|.  |||.|...|                   |
  Fly    77 INEQLIRIDDIIGSRYGRRLKKR--ARGGLNSCR--NPNVPGQEA-------------------D 118

  Fly   134 NIPSDGGDVSAFLYVFAYVLKKRSLRSELHRERTVLTLRFRSFDTFEDNMREADRWYRSLRWQLH 198
            :.|.  .|.||:||::||:.|::.||    |.:|:..|||||.:.:..|::.|:.|:.::|  .|
  Fly   119 SEPD--SDNSAYLYIYAYLKKEKPLR----RVQTLRILRFRSSNDYGVNLQTAEMWHHTIR--KH 175

  Fly   199 RTLEEIFVAPTVDERRRRVLVLLNPKSGSGDAREVFNMHVTPVLNEAEVPYDLYVTKHSNFAIEF 263
            :....   :.:..:..:::|:|||||||||..||:|...|.|:|.||||.|||.:|.|..:|.||
  Fly   176 KRGNG---SSSPADCGKQLLILLNPKSGSGKGRELFQKQVAPLLTEAEVQYDLQITTHPQYAKEF 237

  Fly   264 LSTR--CLDAWCCVVAVGGDGLFHEIVNGLLQRQDWAHVLPHLALGIIPCGSGNGLARSIAHCYN 326
            :.||  .|..:..:|...|||||:|::|||::|.||......|.|||||||||||||:|:||..|
  Fly   238 VRTRRDLLTRYSGIVVASGDGLFYEVLNGLMERMDWRRACRELPLGIIPCGSGNGLAKSVAHHCN 302

  Fly   327 EPYFSKPVLGAALTVISGRSSPMDVVRVQLQSRS----LYSFLSIGWGLISDVDIESERIRMLGY 387
            |||..||:|.|.||.::|:|:|||||||:|.:|.    :|||||:|||||:|:||||||:|.:|.
  Fly   303 EPYEPKPILHATLTCMAGKSTPMDVVRVELATRDKHFVMYSFLSVGWGLIADIDIESERLRSIGA 367

  Fly   388 QRFTVWTLYRLVNLRTYNGRISYLL----------TDHEVSSTHSATGYAAQRRMQSSRSCNTHI 442
            ||||:|.:.||:.||:|.||:||||          ...|:.:..:|.|      ::||...|
  Fly   368 QRFTLWAIKRLIGLRSYKGRVSYLLGKGKKEPPVEAARELPAESTAAG------IRSSLPLN--- 423

  Fly   443 DMLNGPAPIYHSSAEYLPQE-----------FADVISLETSINQSFRSRCDSWLSGGSRRSFYYS 496
                  |..:|.    ||:|           |||.|||:.|:   :|...|||.|..|||:.|||
  Fly   424 ------AGEFHD----LPEEEEGEAVLDGEQFADAISLDRSV---YRQHADSWHSAMSRRTAYYS 475

  Fly   497 I-SESIYHSLADESEFAGLAAASLENRQQNYGPASELPDLNEPLSEDQGWLVEEGEFVMMHAVYQ 560
            : ..|:..:.:..|....:.||:.|..::  .|...:|.|..||....||:.|:|:|||:||.|.
  Fly   476 LGGPSMRSNRSRMSISQRIEAANAEFAER--VPTGTIPPLQMPLLSSDGWICEDGDFVMVHAAYT 538

  Fly   561 THLGIDCHFAPKAQLNDGTIYLILIRAGISRPHLLSFLYNMSSGTHLPESHDDHVKVLPVRAFRL 625
            |||..|..|||:::|:||.|||::||.|:||..||:|:.|:::|||||...|..:||:|.||||:
  Fly   539 THLSSDVFFAPESRLDDGLIYLVIIRRGVSRHQLLNFMLNLNAGTHLPIGEDPFIKVVPCRAFRI 603

  Fly   626 EPYDNHGIITVDGERVEFGPLQAEVLPGIARVM 658
            ||..:.||:.|||||||:||:||||:||:..||
  Fly   604 EPSSSDGILVVDGERVEYGPIQAEVMPGLINVM 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sk2	NP_647762.3	PLN02958	<213..639	CDD:215517	207/453 (46%)
		DAGK_cat	216..354	CDD:279163	78/139 (56%)
Sk1	NP_572717.1	PLN02958	<189..622	CDD:215517	212/456 (46%)
		DAGK_cat	191..330	CDD:279163	78/138 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446751
Domainoid	1	1.000	108	1.000	Domainoid score	I2150
eggNOG	1	0.900	-	-		E1_COG1597
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	200	1.000	Inparanoid score	I1316
Isobase	1	0.950	-	0	Normalized mean entropy	S4295
OMA	1	1.010	-	-		QHG47523
OrthoDB	1	1.010	-	-		D561206at33208
OrthoFinder	1	1.000	-	-		FOG0001465
OrthoInspector	1	1.000	-	-		mtm6496
orthoMCL	1	0.900	-	-		OOG6_101566
Panther	1	1.100	-	-	P	PTHR12358
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R653
SonicParanoid	1	1.000	-	-		X918
	14	13.790