Protein Alignment Sk2 and sphk-1

DIOPT Version :9

• Sequence 1: NP_647762.3
• Gene: Sk2 / 326219
• FlyBaseID: FBgn0052484
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: NP_001022017.1
• Gene: sphk-1 / 183197
• WormBaseID: WBGene00007918
• Length: 473
• Species: Caenorhabditis elegans
• Alignment Length: 446
• Identity: 134/446 - (30%)
• Similarity: 211/446 - (47%)
• Gaps: 82/446 - (18%)

  Fly   208 PTVDERRRRVLVLLNPKSGSGDAREVFNMHVTPVLNEAEVPYDLYVTKHSNFAIEFLSTRC-LDA 271
            |..::.|..:||.:||.||:|.:.|.|...|.|.|:::.:.|::.||...|.|...|.|:. |..
 Worm    79 PPQEQCRGNLLVFINPNSGTGKSLETFANTVGPKLDKSLIRYEVVVTTGPNHARNVLMTKADLGK 143

  Fly   272 WCCVVAVGGDGLFHEIVNGLLQRQDWAHVLPHLALGIIPCGSGNGLARSIAHCYNEPYFSKPVLG 336
            :..|:.:.||||..|.:||:|.|:|...:.|.|.:||:|.||||||..|:...|......|.|:.
 Worm   144 FNGVLILSGDGLVFEALNGILCREDAFRIFPTLPIGIVPSGSGNGLLCSVLSKYGTKMNEKSVME 208

  Fly   337 AALTVISGRSSPMDVV---RVQLQSRSLYSFLSIGWGLISDVDIESERIR-MLGYQRFTVWTLYR 397
            .||.:.:..::..:.|   .|:..::|..|||||||||::|:||:||:.| .||:.||||....|
 Worm   209 RALEIATSPTAKAESVALYSVKTDNQSYASFLSIGWGLMADIDIDSEKWRKSLGHHRFTVMGFIR 273

  Fly   398 LVNLRTYNGRISYLLTDHEVSSTHSATGYAAQRRMQSSRSCNTHIDMLNGPAPIYHSSAEYLPQE 462
            ..|||:|.||::|                                             ..|.|:.
 Worm   274 SCNLRSYKGRLTY---------------------------------------------RPYKPKG 293

  Fly   463 FADVISLETSINQSFRSRCDSWLSGGSRRSFYYSISESIYHSLADESEFAGLAAASLENRQQNYG 527
            |....::.:...::.:.|.|.     |:.....|:|:|       |.|       ::|.:.||:
 Worm   294 FHPSSNVFSVYEKTTQQRIDD-----SKVKTNGSVSDS-------EEE-------TMETKFQNW- 338

  Fly   528 PASELPDLNEPL----SEDQGWLVEEGEFVMMHAVYQTHLGIDCHFAPKAQLNDGTIYL--ILIR 586
               .|||.:|.|    |:.:..:|.|..||.::||..:|:..|..|||.|:|.|..|:|  ||.:
 Worm   339 ---TLPDSDETLAVGSSDLEETVVIEDNFVNIYAVTLSHIAADGPFAPSAKLEDNRIHLSYILWK 400

  Fly   587 AGISRPHLLSFLYNMSSGTHLPESHDDHVKVLPVRAFRLEPYDNHGIITVDGERVE 642
            ...:|.::..:|..:...|||......||:   |.:.:||.......:.:|||.|:
 Worm   401 DIGTRVNIAKYLLAIEHETHLDLPFVKHVE---VSSMKLEVISEGSHVVLDGEVVD 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sk2	NP_647762.3	PLN02958	<213..639	CDD:215517	130/436 (30%)
		DAGK_cat	216..354	CDD:279163	49/141 (35%)
sphk-1	NP_001022017.1	DAGK_cat	88..>189	CDD:279163	40/100 (40%)
		LCB5	89..469	CDD:224513	132/436 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158680
Domainoid	1	1.000	115	1.000	Domainoid score	I3774
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	204	1.000	Inparanoid score	I2443
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D561206at33208
OrthoFinder	1	1.000	-	-		FOG0001465
OrthoInspector	1	1.000	-	-		otm14570
orthoMCL	1	0.900	-	-		OOG6_101566
Panther	1	1.100	-	-	O	PTHR12358
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X918
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.900