Protein Alignment Sk2 and Sphk1

DIOPT Version :9

• Sequence 1: NP_647762.3
• Gene: Sk2 / 326219
• FlyBaseID: FBgn0052484
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: NP_001257740.1
• Gene: Sphk1 / 170897
• RGDID: 620048
• Length: 458
• Species: Rattus norvegicus
• Alignment Length: 442
• Identity: 135/442 - (30%)
• Similarity: 198/442 - (44%)
• Gaps: 107/442 - (24%)

  Fly   216 RVLVLLNPKSGSGDAREVFNMHVTPVLNEAEVPYDLYVTKHSNFAIEFLSTRCLDAWCCVVAVGG 280
            ||||||||:.|.|.|.::|...|.|:|.||||.:.|.:|:..|.|.|.:....|..|..:..:.|
  Rat    91 RVLVLLNPRGGKGKALKLFQSRVRPLLEEAEVSFKLMLTERQNHARELVCAEELGHWDALAVMSG 155

  Fly   281 DGLFHEIVNGLLQRQDWAHVLPHLALGIIPCGSGNGLARSIAHCYNEPYFSKP--VLGAALTVIS 343
            |||.||:||||::|.||...: ...|..:|.||||.||.|:.:.......:..  ::...|.:..
  Rat   156 DGLMHEVVNGLMERPDWESAI-QKPLCSLPGGSGNALAASLNYYAGHEQVTNEDLLINCTLLLCC 219

  Fly   344 GRSSPMDVVRVQLQS-RSLYSFLSIGWGLISDVDIESERIRMLGYQRFTVWTLYRLVNLRTYNGR 407
            .:.|||:::.:...| |.|||.||:.||.::|||:|||:.|.||..||||.|.:||.:||.|.|:
  Rat   220 RQLSPMNLLSLHTASGRQLYSVLSLSWGFVADVDLESEKYRSLGEIRFTVGTFFRLASLRIYQGQ 284

  Fly   408 ISYLLTDHEVSSTHSATGYAAQRRMQSSRSCNTHIDMLNGPAPIYHSSAEYLPQEFADVISLETS 472
            ::||           ..|.||.:
  Rat   285 LAYL-----------PVGKAASK------------------------------------------ 296

  Fly   473 INQSFRSRCDSWLSGGSRRSFYYSISESIYHSLADESEFAGLAAASLENRQQNYGPASE-LPDLN 536
                                                     :.|:||..:    |||:. |..|.
  Rat   297 -----------------------------------------IPASSLAQK----GPANTYLVPLE 316

  Fly   537 EPLSEDQGW-LVEEGEFVMMHAVYQTHLGIDCHFAPKAQLNDGTIYLILIRAGISRPHLLSFLYN 600
            ||:...  | :|.|.:||::..:..|||..:...||..:...|.::|..||||:||..||.....
  Rat   317 EPVPPH--WTVVPEQDFVLVLVLLHTHLSTEMFAAPMGRCEAGVMHLFYIRAGVSRAMLLRLFLA 379

  Fly   601 MSSGTHLPESHDDHVKVLPVRAFRLEPYDNHGIITVDGERVEFGPLQAEVLP 652
            |..|.|: :....::..:||.||||||.:..|:.:||||.:....:|.:|.|
  Rat   380 MQKGKHM-DLDCPYLVHVPVVAFRLEPRNQRGVFSVDGELMVCEAVQGQVHP 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sk2	NP_647762.3	PLN02958	<213..639	CDD:215517	130/427 (30%)
		DAGK_cat	216..354	CDD:279163	52/139 (37%)
Sphk1	NP_001257740.1	LCB5	91..443	CDD:224513	135/442 (31%)
		DAGK_cat	91..197	CDD:279163	48/106 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339908
Domainoid	1	1.000	101	1.000	Domainoid score	I6760
eggNOG	1	0.900	-	-		E1_COG1597
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H39748
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D561206at33208
OrthoFinder	1	1.000	-	-		FOG0001465
OrthoInspector	1	1.000	-	-		otm46146
orthoMCL	1	0.900	-	-		OOG6_101566
Panther	1	1.100	-	-	O	PTHR12358
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X918
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.710