Protein Alignment Sk2 and LOC1273031

DIOPT Version :10

• Sequence 1: NP_647762.3
• Gene: Sk2 / 326219
• FlyBaseID: FBgn0052484
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: XP_563184.4
• Gene: LOC1273031 / 1273031
• VectorBaseID: AGAMI1_007656
• Length: 637
• Species: Anopheles gambiae
• Alignment Length: 724
• Identity: 148/724 - (20%)
• Similarity: 251/724 - (34%)
• Gaps: 245/724 - (33%)

  Fly    27 DEGHDVSDTFYTSQRKKGSHVFRVRLDATGFTLQRESPGGSIVKEQHVRISDIVGARCMR-PKKS 90
            |:.|:|....:...:|:    :||..:|.....:.||   |...:..|.|:|::.....: |..:
Mosquito     2 DKEHEVLLNAFVIAKKR----YRVFYNAGILVWEDES---SKKAKTTVPITDVLSVSVSKLPHAN 59

  Fly    91 RR--LAMSGACACSSGNPNSPAIS-------ASGDHHR-----PATTPSKCSTNSRDNIPS---- 137
            .:  :..|.|.|.:...|:.||.:       .|.|..|     .:||.:..:|.| .|||.
Mosquito    60 GKQWMKRSKAAAAAPPPPHPPAAAIVRNEAHGSLDSDRIPVLSGSTTTNTLATTS-SNIPHNHSN 123

  Fly   138 -------------------DGGDVSA------FLYVFAYVLKKRSLRSELHRERTVLTLRFRSFD 177
                               |.|.:.|      .|:..|.|.:|.:            ..|.|:..
Mosquito   124 RGSLNDLSDDDRREASDYLDAGTIQAADFKYLILHYAALVCQKTN------------RWRVRAVA 176

  Fly   178 TFEDNMREADRWYRSLRWQLHRTLEEIFVAPTVDERR-RRVLVLLNPKSGSGDAREVFNMHVTPV 241
            ......|..:.||..|...|.            |:.| :.:|:.|||..|..:|..::..:..|:
Mosquito   177 LHNSEPRLVELWYNRLSSDLR------------DQNRPKHLLLFLNPYGGKKNALALYERYAKPL 229

  Fly   242 LNEAEVPYDLYVTKHSNFAIEFLSTR--CLDAWCCVVAVGGDGLFHEIVNGLLQRQDW------- 297
            ...|.|..:|.:|:.:....:.::::  .||.:..:|..||||.|.|:.|||:.|...
Mosquito   230 FRLAGVDINLIITQRAQQIYDIVTSKSILLDNYDGLVCCGGDGTFAELFNGLVTRTMMDCGIDIK 294

  Fly   298 --AHV-LPHLALGIIPCGSGNGLARSIAHCYNEPYFSKPVLGAALTVISGRSSPMDVVRV----- 354
              |:: .|::.:|:||.||.:    ::|.|.|.   :..:....:.:|.|:.|.:|:..|
Mosquito   295 YPAYLPKPNIPIGVIPAGSTD----TVACCLNG---TTDIKTCIIHIILGQHSGLDISAVYSADA 352

  Fly   355 --------------QLQSRSLYSFLS-IGWGLISDVDIESERIRMLGYQRFTVWTLYRLVNLRTY 404
                          :.:.:.|..|.| :.:|.:.|:..:||:.|.:|.:|:......:.:..|.|
Mosquito   353 AAKCDEGASPAGTGRPRPQLLKLFASALSYGYLGDIAYDSEKYRWMGPKRYDYSGFKKFLANRGY 417

  Fly   405 NGRISYLLTDHEVSSTHSATGYAAQRRMQSSRSCNTHIDMLNGPAPIYHSSAEYLPQEFADVISL 469
            |..|.                              .|:|......|
Mosquito   418 NAEIV------------------------------VHLDRRGKQDP------------------- 433

  Fly   470 ETSINQSFR-----SRCDSWLSGGSRRSFYYSISESIYHSLADESEFAGLAAASLENRQQNYGPA 529
                |...|     :||        |::.|              ....|...||.|:
Mosquito   434 ----NDGVRCLDKCARC--------RKAKY--------------GRDCGGERASYED-------- 464

  Fly   530 SELPDLNEPLSEDQGWLVEEGEFVMMHAVYQTHLGIDCH-----FAPKAQLNDGTIYLILIRAGI 589
                |..||       ||..|:|:|   |...::...|.     |:|...|.||.:.|:|:| ..
Mosquito   465 ----DDTEP-------LVVRGKFLM---VSGANISCSCERSPQGFSPYCHLGDGLLDLVLVR-HT 514

  Fly   590 SRPHLLSFLYNMSSGT----HLPESHDDHVKVLPVRAFRLEPYDNHGIITVDGERVEFGPLQAEV 650
            |..:.|..|..|:|.|    .||     .|::...:.||         .|.:|:....|   .|:
Mosquito   515 SMFNNLRLLLTMTSKTKKLSELP-----FVEIYRTKEFR---------FTANGQSETNG---GEI 562

  Fly   651 LPGIARVMV 659
            .|.|:..|:
Mosquito   563 APAISSEMM 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sk2	NP_647762.3	PLN02958	<213..639	CDD:215517	97/472 (21%)
LOC1273031	XP_563184.4	DAGK_cat	<188..611	CDD:445337	108/518 (21%)