Protein Alignment Sk2 and sphk1

DIOPT Version :9

• Sequence 1: NP_647762.3
• Gene: Sk2 / 326219
• FlyBaseID: FBgn0052484
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: XP_002667585.3
• Gene: sphk1 / 100331840
• -ID: -
• Length: 493
• Species: Danio rerio
• Alignment Length: 667
• Identity: 190/667 - (28%)
• Similarity: 275/667 - (41%)
• Gaps: 219/667 - (32%)

  Fly    25 DADEGH-----DVSDTFYTSQRKKGSHVFRVRLDATGFTLQRESPGGSIVKEQHVRISDIVGARC 84
            |||.|.     .:||:..|.||.                   .||.......:|:.:.|.:|:|.
Zfish    12 DADTGRLTYALSLSDSCLTVQRV-------------------SSPPSQTPAPEHLDLRDCLGSRA 57

  Fly    85 MRPKKSRRLAMSGACACSSGNPNSPAISASGDHHRPATTPSKCSTNSRDNIPSDGGDVSAFLYVF 149
            .|.::..|.|.                                                 :|.|:
Zfish    58 HRGEREDRDAY-------------------------------------------------YLCVY 73

  Fly   150 AYVLKKRSLRSELHRERTVLTLRFRSFDTFEDN---------------MREADRWYRSLRWQLHR 199
            .|..::|.:.....|:|.  ..|||.....:||               :|||:||.|::|.:...
Zfish    74 FYPYRRRWMAWGPVRQRD--ERRFRLVLNSDDNNDDEQEEEDEEEDAKLREAERWARAIRNRPGN 136

  Fly   200 TLEEIFVAPTVDERRRR--VLVLLNPKSGSGDAREVFNMHVTPVLNEAEVPYDLYVTKHSNFAIE 262
            |...:|     .|.||.  |:||:||:||.|.|...:|.||..:|.||::|:.|.:|:..|.|.:
Zfish   137 TRGVLF-----SEVRRACGVMVLVNPQSGRGQAMAQYNGHVQRMLTEADIPHTLVITERQNHARD 196

  Fly   263 FLSTRCLDAWCCVVAVGGDGLFHEIVNGLLQRQDWAHVLPHLALGIIPCGSGNGLARSIAHCYNE 327
            .:.:..|..|..::.:.||||..|:||||::|.||...: ...|||:|.||||.||.|:.| |..
Zfish   197 LVRSTDLSQWDALIILSGDGLLFEVVNGLMERPDWEKAI-QTPLGILPGGSGNALAASVHH-YTR 259

  Fly   328 PYFSKPVLGAAL------TVISGRSSPMDVVRVQLQSRS-LYSFLSIGWGLISDVDIESERIRML 385
               :.||.|..|      .:..|..|.:|::.|||.|.: |:||||:.||.::|||||||..|.:
Zfish   260 ---ASPVWGEDLLTSCGFLLCKGLVSGLDLISVQLSSGARLFSFLSLAWGFVADVDIESETFRQI 321

  Fly   386 GYQRFTVWTLYRLVNLRTYNGRISYL---LTDHEVSSTHSATGYAAQRRMQSSRSCNTHIDMLNG 447
            |..||.:.||.||.:||.|.|:::||   .|| .||||             .....|.|:
Zfish   322 GALRFILGTLVRLASLRIYQGKLAYLPAGETD-SVSST-------------GENLLNDHL----- 367

  Fly   448 PAPIYHSSAEYLPQEFADVISLETSINQSFRSRCDSWLSGGSRRSFYYSISESIYHSLADESEFA 512
                                                                             
Zfish   368 ----------------------------------------------------------------- 367

  Fly   513 GLAAASLENRQQNYGPASELPDLNEPLSEDQGW-LVEEGEFVMMHAVYQTHLGIDCHFAPKAQLN 576
                               :....:|:  .|.| ||||.|||::.|::|:||..|...||.|:.:
Zfish   368 -------------------MAPFGQPV--PQNWTLVEEREFVLVLAMFQSHLSEDLMAAPGARAD 411

  Fly   577 DGTIYLILIRAGISRPHLLSFLYNMSSGTHLPESHDDHVKVLPVRAFRLEPYDNHGIITVDGERV 641
            ||.|:|..:.||:||..||.....|.||||| :....|:..:..:|.||||....|::|||||||
Zfish   412 DGIIHLFYLTAGVSRATLLRLFRAMQSGTHL-DCGCAHLVYVRAQAIRLEPLSADGVLTVDGERV 475

  Fly   642 EFGPLQAEVLPGIARVM 658
            .:||:||:|....||::
Zfish   476 HYGPVQAQVHRAAARII 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sk2	NP_647762.3	PLN02958	<213..639	CDD:215517	140/438 (32%)
		DAGK_cat	216..354	CDD:279163	54/145 (37%)
sphk1	XP_002667585.3	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579707
Domainoid	1	1.000	107	1.000	Domainoid score	I6447
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H39748
Inparanoid	1	1.050	290	1.000	Inparanoid score	I2781
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D561206at33208
OrthoFinder	1	1.000	-	-		FOG0001465
OrthoInspector	1	1.000	-	-		mtm6496
orthoMCL	1	0.900	-	-		OOG6_101566
Panther	1	1.100	-	-	O	PTHR12358
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X918
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.900