| Sequence 1: | NP_996141.2 | Gene: | SMC5 / 326215 | FlyBaseID: | FBgn0052438 | Length: | 1034 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001002800.1 | Gene: | SMC4 / 10051 | HGNCID: | 14013 | Length: | 1288 | Species: | Homo sapiens |
| Alignment Length: | 1258 | Identity: | 256/1258 - (20%) |
|---|---|---|---|
| Similarity: | 458/1258 - (36%) | Gaps: | 341/1258 - (27%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 6 ALSSKQLAGR--IHSVYCKDFVSYS-EITFHPKH-YLNVLTGPNGSGKSTIVSAIILGLGGEPIL 66
Fly 67 LDRSASVADYIQSNKTSATI------------IVRV------------YGRTPNTTETFRRIINS 107
Fly 108 NGLSTFSVNDKDTSKKNFLAAVSSFNIQVSNLCQFLPQDRVQDFSKMNPQ------ELLLNTMSS 166
Fly 167 VCDEDLINSFNSLKQMRTEQANVHANREKEKSDLVKKQK---------RLEHLQMTVSQYKEREE 222
Fly 223 VKQKLQVYSAKKLWVETQAGEAK---------------AAEMKTQVKNAK--------------- 257
Fly 258 -----TQSD--------KLKNQHDKLLQSQEQIEKEKESLRK---------ALLEKTRLLENAVA 300
Fly 301 EKAAIDGK-----MDSLK---QGIYQKKYELEQNIKKSRRTATECDNLNQLVENKIYELETLNKS 357
Fly 358 RPLIVSELERAKESCAAARGKAMEQYSRRRQLEQKL---------NDEMIPEITAYKLKIERLRN 413
Fly 414 VKMQKIDEIRAKNPNLVVAMNWLAQNKQRYKLNVYDPMILELTVQNHEDAKFLENVVAQRDLFAF 478
Fly 479 ACEDKGDMS----------------DLINELCV----KQKLGVNVIYCAPSDRLVYSPK-----T 518
Fly 519 PIDDLRSFGFRSYLVDLVTGPIPLINKLCASYSIHNIPIGTEAVGNYTSSIPKAIRVYF------ 577
Fly 578 ------------------GGSKKFVVTASRYRSDTI--LTESSIRAKNQLITVDSQQLALVMK-- 620
Fly 621 -QCSEAV---------------KESDSIKNAITQTD------NEFERLQAVAKDEQEKRRKLDQK 663
Fly 664 IAHFNSLKTEIETLQKK-------LEALRNS-------------DSLDCL--ETNFCNS------ 700
Fly 701 -------------------LHKDL----KKIFDADAELCSCLKAIDRLIIEKNMAQTKVSIYMLQ 742
Fly 743 HETQIEALKESEEQSKAATRDFQQLLQCLENQISDVNKRKSAIQGLCHGEIPTSSKFPFKKEFRE 807
Fly 808 LENIDL--PELREAIHD----------FQARLECMKSVNSEAISSYQGLQNEVKQLEEGIQESVN 860
Fly 861 QAKSI----ESGMSNLYDKWEPKLNSLVE---TISTKFSEFMESIEYVGEVVLSKTDKYDFDSYG 918
Fly 919 IQIMVQFRRGLQLQPLDK-----FIQSGGERAVSIAIYSLSLQHVTHVPFRCVDEINQGMDATNE 978
Fly 979 RHIFDLLLKEATKHGSAQYLFVT 1001 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| SMC5 | NP_996141.2 | ABC_SMC5_euk | 14..>160 | CDD:213244 | 39/179 (22%) |
| Smc | 22..1011 | CDD:224117 | 252/1240 (20%) | ||
| GrpE | 212..>316 | CDD:295646 | 32/163 (20%) | ||
| ABC_SMC5_euk | <919..1025 | CDD:213244 | 24/88 (27%) | ||
| SMC4 | NP_001002800.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..55 | ||
| ABC_SMC4_euk | 82..>241 | CDD:213241 | 36/168 (21%) | ||
| SMC_N | 83..1274 | CDD:280601 | 253/1247 (20%) | ||
| DUF4349 | <327..427 | CDD:305044 | 20/99 (20%) | ||
| SMC_hinge | 613..727 | CDD:214944 | 23/133 (17%) | ||
| ABC_SMC4_euk | <1181..1275 | CDD:213241 | 21/73 (29%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG1196 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||