DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32379 and AGBL2

DIOPT Version :9

Sequence 1:	NP_729252.2	Gene:	CG32379 / 326211	FlyBaseID:	FBgn0052379	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_079059.2	Gene:	AGBL2 / 79841	HGNCID:	26296	Length:	902	Species:	Homo sapiens

Alignment Length:	270	Identity:	60/270 - (22%)
Similarity:	98/270 - (36%)	Gaps:	81/270 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 IQWPHIDVLSAF------YTHSEINDYLDSLLERFPKRVQ---VKQFGWSYERRPLKVLTITNGD 88
            ||:|: |..:.|      ||::::..||.|:... |.:.|   ::....|.....:.:|||||..
Human   381 IQFPY-DQDTCFFAHFYPYTYTDLQCYLLSVANN-PIQSQFCKLQTLCRSLAGNTVYLLTITNPS 443

  Fly    89 GRRN----KPVILIDGTVHARE----WISPSMALYIIQQLLDNYGDNQELLQDYDWVIMPVVNAD 145
            ....    |..:::...||..|    |:......:|    |.|..|.|.|...:.:.::|::|.|
Human   444 QTPQEAAAKKAVVLSARVHPGESNGSWVMKGFLDFI----LSNSPDAQLLRDIFVFKVLPMLNPD 504

  Fly   146 GYEYTHTDSRYWRKSRRPTSNPEC--IGTDINRNFGYEWGHDEGSSSDPC----ENIYRGERPFD 204
            |.               ...|..|  .|.|:||::     ......|.||    .|:.:  |..:
Human   505 GV---------------IVGNYRCSLAGRDLNRHY-----KTILKESFPCIWYTRNMIK--RLLE 547

  Fly   205 QSESQVLRDVMLHYKGRLNFYLSLHSY---GNYFLLP--------WGYTSDFPDTYQDMMSVADA 258
            :      |:|:|        |...|.:   .|.||..        |.:...||     :|...:|
Human   548 E------REVLL--------YCDFHGHSRKNNIFLYGCNNNNRKYWLHERVFP-----LMLCKNA 593

  Fly   259 GAKAIIYSTN 268
            ..|...:|.|
Human   594 PDKFSFHSCN 603

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32379	NP_729252.2	M14_CP_A-B_like	44..338	CDD:199844	56/259 (22%)
AGBL2	NP_079059.2	GVQW	105..>120	CDD:290611
		M14_AGBL2-3_like	407..666	CDD:133117	52/243 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	746..770
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	796..879
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900