DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32379 and Agbl2

DIOPT Version :9

Sequence 1:	NP_729252.2	Gene:	CG32379 / 326211	FlyBaseID:	FBgn0052379	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_848870.2	Gene:	Agbl2 / 271813	MGIID:	2443254	Length:	862	Species:	Mus musculus

Alignment Length:	302	Identity:	66/302 - (21%)
Similarity:	110/302 - (36%)	Gaps:	74/302 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 QWPHIDVLSAF------YTHSEINDYLDSLLERFPKRVQ---VKQFGWSYERRPLKVLTITNGDG 89
            |:|| |..:.|      ||::::..||.|:... |.:.|   ::....|.....:.:|||||...
Mouse   345 QFPH-DQDTCFFAHFYPYTYTDLQCYLLSVANN-PIQSQFCKLRALCRSLAGNTVYLLTITNPSR 407

  Fly    90 RRN----KPVILIDGTVHARE----WISPSMALYIIQQLLDNYGDNQELLQDYDWVIMPVVNADG 146
            ...    |..:::...||..|    ||......:|    |.|..|.|.|...:.:.::|::|.||
Mouse   408 TPQEAAAKKAVVLSARVHPGESNSSWIMNGFLDFI----LSNSPDAQLLRDIFVFKVIPMLNPDG 468

  Fly   147 YEYTHTDSRYWRKSRRPTSNPEC--IGTDINRNFGYEWGHDEGSSSDPC----ENIYRGERPFDQ 205
            .               ...|..|  .|.|:||::     ......|.||    :|:.:  |..::
Mouse   469 V---------------IVGNYRCSLAGRDLNRHY-----KTVLKDSFPCIWYTKNMIK--RLLEE 511

  Fly   206 SESQVLRDVMLHYKGRLNFYLSLHSYGNYFLLPWGYTSDFPDTYQDMMSVADAGAKAIIYSTNGI 270
            .|..:..|...|.:....|....||.....   |.:...||     :|...:|..|
Mouse   512 REVLLYCDFHGHSRKNNIFLYGCHSNNRKH---WLHERVFP-----LMLSKNAPDK--------- 559

  Fly   271 YSYGSTYYVLYPT---SGDTTDFAFGVVNATVAMTMELPAAG 309
            :|:.|..:.:...   :|....:..|::|   :.|||....|
Mouse   560 FSFDSCNFKVQKCKEGTGRVVMWRMGIIN---SYTMESTFGG 598

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32379	NP_729252.2	M14_CP_A-B_like	44..338	CDD:199844	62/292 (21%)
Agbl2	NP_848870.2	Pepdidase_M14_N	231..358	CDD:375499	5/13 (38%)
		M14_AGBL2-3_like	379..629	CDD:349478	55/266 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	669..692
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	704..728
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	750..836
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900