DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32379 and ZC434.9

DIOPT Version :9

Sequence 1:	NP_729252.2	Gene:	CG32379 / 326211	FlyBaseID:	FBgn0052379	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_001251356.1	Gene:	ZC434.9 / 172908	WormBaseID:	WBGene00013895	Length:	720	Species:	Caenorhabditis elegans

Alignment Length:	376	Identity:	105/376 - (27%)
Similarity:	190/376 - (50%)	Gaps:	48/376 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRNYHLEYKVLIEDLAPLV----HA-QRAENLRKKLLIQWPHID-------VLSAFYTHSEINDY 53
            ::|.::.|.|:|||:..|:    |. .|..||   |..:..|.:       ....::::..|.|:
Worm    89 LKNSNISYDVIIEDVGKLILEKEHGPPRFSNL---LFSKRMHNEGGNRARYGFGEYHSYQTICDW 150

  Fly    54 LDSLLERFPKRVQVKQFGWSYERRPLKVLTITNGDGRRNKPVILIDGTVHAREWISPSMALYIIQ 118
            :..:..::|.:.:|...|.:.|.||::.:.|.:...|.:|.:..|||.:|||||.:...||:.|.
Worm   151 MKDIERKYPDKAKVFTMGTTSEGRPIQGIKIGSQVWRNDKRIFWIDGGIHAREWAAVHTALWFID 215

  Fly   119 QLLDNYGDN---QELLQDYDWVIMPVVNADGYEYTHTD----SRYWRKSR--------RPTSNPE 168
            :|:.:|.|:   :..:...::.|:||.|.|||||:.:|    .|.|||:|        |...:..
Worm   216 RLIADYNDDSLVRAAVDRLNFYILPVANPDGYEYSRSDVSPMIRLWRKNRAGVVCKKDRWFRDRC 280

  Fly   169 CIGTDINRNFGYEWGHDEGSSSDPCENIYRGERPFDQSESQVLRDVML--HYKGRLNFYLSLHSY 231
            |.|.|:|||:.:.:| :.|||:|.|..||:|...|.:||::.:||.:.  ...|:::.:::||:|
Worm   281 CGGVDLNRNYDWHFG-ETGSSTDKCSEIYQGSSAFSESETRSMRDFLTSSELNGKIDAFITLHTY 344

  Fly   232 GNYFLLPWGYT-SDFPDTYQDMMSVADAGAKAI--IYSTNGIYSYGSTYYVLYPTSGDTTDFAFG 293
            ...::.|:.:. ...|....::..|..|...|:  .|.|.  |.:|:...:|||::|.:.|:|.|
Worm   345 SQMWIHPYSHARKSVPADVAELQRVGRAAVAALENTYGTK--YKFGTGSDILYPSAGGSDDWAKG 407

  Fly   294 VVNATVAMTMELPAAGFQGFDPW----ISQIERLVT--ESWVGVRAMAAEV 338
            .:.......:||.    .|.|.|    :.|.:.:.|  |:|.|::.:...|
Worm   408 TLRIKYVYLLELR----PGEDVWDGFILDQHQLIPTAKETWNGIKVVIRAV 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32379	NP_729252.2	M14_CP_A-B_like	44..338	CDD:199844	91/319 (29%)
ZC434.9	NP_001251356.1	Propep_M14	45..111	CDD:366995	7/21 (33%)
		M14_CP_A-B_like	141..454	CDD:349433	91/319 (29%)
		ShK	682..719	CDD:366702
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.020