DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32379 and T06A4.3

DIOPT Version :9

Sequence 1:	NP_729252.2	Gene:	CG32379 / 326211	FlyBaseID:	FBgn0052379	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_001021611.1	Gene:	T06A4.3 / 171668	WormBaseID:	WBGene00020283	Length:	505	Species:	Caenorhabditis elegans

Alignment Length:	366	Identity:	119/366 - (32%)
Similarity:	188/366 - (51%)	Gaps:	39/366 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LEYKVLIEDLAPLVHAQRAENLRKKLLIQWPHI--DVLSAFY------THSEINDYLDSLLERFP 62
            :.|...|:|:..|:  .:.|| .|.|...:|.:  |..||.|      ::..:.|::..|:.::|
Worm    85 ISYIKTIDDVEGLI--TKHEN-NKTLSNMFPRLWDDSSSAHYDFHTYGSYQRMTDWMKQLVVKYP 146

  Fly    63 KRVQVKQFGWSYERRPLKVLTITNGDGRRNKPVILIDGTVHAREWISPSMALYIIQQLLD--NYG 125
            |.||....|.:.|.|.:..:.|  |...|.|.:..|||.:|||||.:|..||:.|.||..  |..
Worm   147 KMVQYISIGKTTEGRNIDGVEI--GGDSRTKKIFWIDGGIHAREWAAPHTALFFIHQLTSRANEP 209

  Fly   126 DNQELLQDYDWVIMPVVNADGYEYTHTDS----RYWRKSRRPTS--------NPECIGTDINRNF 178
            ..::||.:..:|::|.:|.||||:|.:.:    |.|||:|....        |..|.|.|:||||
Worm   210 GIKKLLNEITFVVVPCLNPDGYEFTRSSTNPHVRLWRKNRSKMQCRKDIWGRNRCCRGVDLNRNF 274

  Fly   179 GYEWGHDEGSSSDPCENIYRGERPFDQSESQVLRDVML--HYKGRLNFYLSLHSYGNYFLLPWGY 241
            .:.: .:.|:|.|||..||:|..||.:.|::.:||.:|  .||||.:.|::||:|...::.|:|:
Worm   275 DFHF-RESGTSDDPCSEIYQGPSPFSEPEAKAVRDALLSQRYKGRTDAYITLHTYSQIWIHPYGH 338

  Fly   242 TSD-FPDTYQDMMSVADAGAKAI--IYSTNGIYSYGSTYYVLYPTSGDTTDFAFGVVNATVAMTM 303
            ..| :|...:|:..|....|:|:  :|.|.  |..||....|||.||.:.|:|...........:
Worm   339 KKDAYPGDIKDLYEVGKKAAQALKRVYGTK--YVVGSGADTLYPASGGSEDWAKHEAKVKFVYLL 401

  Fly   304 ELPAAGFQGFDPWISQIERLV---TESWVGVRAMAAEVIRR 341
            || ....:.:|.:|...:.|:   .|:|.|||.:|..|:.|
Worm   402 EL-RPDEKNWDGFILDEKELIPTARETWEGVRVVAEAVLDR 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32379	NP_729252.2	M14_CP_A-B_like	44..338	CDD:199844	105/321 (33%)
T06A4.3	NP_001021611.1	Propep_M14	31..98	CDD:366995	3/12 (25%)
		M14_CP_A-B_like	128..438	CDD:349433	104/315 (33%)
		ShK	468..505	CDD:366702
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47975
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.030