DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32379 and Y18H1A.9

DIOPT Version :9

Sequence 1:	NP_729252.2	Gene:	CG32379 / 326211	FlyBaseID:	FBgn0052379	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_490776.2	Gene:	Y18H1A.9 / 171666	WormBaseID:	WBGene00021213	Length:	488	Species:	Caenorhabditis elegans

Alignment Length:	375	Identity:	118/375 - (31%)
Similarity:	201/375 - (53%)	Gaps:	50/375 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 NYHLEYKVLIEDLAPLV--HAQRAENLRKKL-LIQWPHIDV---LSAFYTHSEINDYLDSLLERF 61
            ::.:::.|:|:|:..::  ..::.:.|||:: |..|....|   |:.:::.:::.:||:||...:
Worm    78 DHSIKHSVMIDDVQKVIVEQKEKRDKLRKQVRLHDWREQKVQFNLAQYHSFADVINYLNSLAITY 142

  Fly    62 PKRVQVKQFGWSYERRPLKVLTITNGDGRRNKPVILIDGTVHAREWISPSMALYIIQQLLDNYGD 126
            |:.|.|:..|.::|.|.:.::.|||......|..|.:||.:|||||:|||..||.|.||:..|..
Worm   143 PELVSVQPIGTTHEGRQIPLIKITNKRNGGTKRGIWVDGGIHAREWVSPSTVLYFIHQLVTQYDK 207

  Fly   127 NQELLQDYD---WVIMPVVNADGYEYTHTDS----RYWRKSRRPTSNPECI-------------- 170
            :.::.|..|   |.|:|::|.|||||:.:.:    |.|||:|.|   |:||
Worm   208 DVQIKQFVDQLEWYIVPLLNPDGYEYSRSSNDPEIRLWRKNRSP---PKCIQQATGLFQPPTTTC 269

  Fly   171 --GTDINRNFGYEWGHDEGSSSDPCENIYRGERPFDQSESQVLRDVMLHYKGRLNFYLSLHSYGN 233
              |.|:||||.:.:| ..|||:|||..||:|...|.:.|:..:||.:..:  |::.:|:.|||..
Worm   270 CQGVDLNRNFDWFFG-QVGSSTDPCSEIYQGAYAFSEPETAAVRDFVQRH--RISTFLTFHSYSQ 331

  Fly   234 YFLLPWG-----YTSDFPDTYQDMMSVADAGAKAI--IYSTNGIYSYGSTYYVLYPTSGDTTDFA 291
            ..:.|:|     |::|.    .|:.|.|.:.|:|:  :|:|.  |..|:....|||.||.:.|:|
Worm   332 ILMYPFGHQVRTYSNDL----NDLRSTALSAAQALNSVYNTQ--YKVGTGADTLYPASGGSEDWA 390

  Fly   292 FGVVNATVAMTMEL--PAAGFQGFDPWISQIERLVTESWVGVRAMAAEVI 339
            .|..:...:...||  ....:.||....:||.....|:|..|:.:|::.|
Worm   391 KGKAHVKYSFLFELRPEEQVWDGFLLAENQIIPTARETWEAVKVIASKTI 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32379	NP_729252.2	M14_CP_A-B_like	44..338	CDD:199844	107/325 (33%)
Y18H1A.9	NP_490776.2	Propep_M14	29..97	CDD:366995	3/18 (17%)
		M14_CP_A-B_like	125..436	CDD:349433	106/322 (33%)
		ShKT	454..487	CDD:214586
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47975
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.930