Protein Alignment CG9903 and SLC10A3

DIOPT Version :10

• Sequence 1: NP_573132.1
• Gene: CG9903 / 32621
• FlyBaseID: FBgn0030756
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: XP_006724910.1
• Gene: SLC10A3 / 8273
• HGNCID: 22979
• Length: 570
• Species: Homo sapiens
• Alignment Length: 486
• Identity: 111/486 - (22%)
• Similarity: 201/486 - (41%)
• Gaps: 93/486 - (19%)

  Fly     1 MGNVNKNIGRLLVAVGVLMIL----GLQGVRSEYGDLAGNWLV-----------DYDRDELNFFE 50
            :|......|.|.:....|:::    |.||..|.....||...|           |....|..|.|
Human   109 LGGEGGGTGPLSMLRAALLLISLPWGAQGTASTSLSTAGGHTVPPTGGRYLSIGDGSVMEFEFPE 173

  Fly    51 DSTWSVDLHIYNVLPKDSSLDYYFVVYSKDDRRASSPPLEIKKEDFDLLG-------SW-RGALY 107
            ||...:.:          |..|    ..:.:|.|..|.|.:...|.::|.       :| .|..:
Human   174 DSEGIIVI----------SSQY----PGQANRTAPGPMLRVTSLDTEVLTIKNVSAITWGGGGGF 224

  Fly   108 VTGVRFGYSSLEVELKSGAVTETYPKPLPITVLRTQ-----VVDER------------ITTYVSA 155
            |..:..|.:.|              .||.|.::...     :::||            ....:||
Human   225 VVSIHSGLAGL--------------APLHIQLVDAHEAPPTLIEERRDFCIKVSPAEDTPATLSA 275

  Fly   156 ALA------------LLMFLN---LGTVLDMQRLAGIICRPVGPVVGVVSRFVLMPAVGFGLGRA 205
            .||            .|:|:|   .|..::::.|.|::..|...::|::.:|::||...|.:.:.
Human   276 DLAHFSENPILYLLLPLIFVNKCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPLYAFLMAKV 340

  Fly   206 -LWPDSWPLQLALFYTALSPSGGLANVCAVFLKGNINLSVATTTINSLLALALLPIWILVLGRIL 269
             :.|.:  |.|.|..|..||.||.:.:.::.|.|::.|:::.|.::::.|...||:...:..|:|
Human   341 FMLPKA--LALGLIITCSSPGGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFLPLSSAIYSRLL 403

  Fly   270 YEDDELTVPFGQLSGGAAALVACLAIGVLLRLCLPRTTRFIFRFLKPLSVVLSLCLVGLTVGLNS 334
            ...:.|.||..::.|....:...:|:|||::..||:.::.:.:.:||.|.||.|..:.|...:..
Human   404 SIHETLHVPISKILGTLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFSFVLLLGGLFLAYRMGV 468

  Fly   335 FVFYEFTWQILVAAVCLPLAGYLSTYLLSKILCRSSTDALTLAIEASVLNMTMPIVLLQSSQLQQ 399
            |:.......|::..:.:||.|.|..|.|:..|........|::||..|.|..:.:.:||.| |::
Human   469 FILAGIRLPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSIEVGVQNSLLALAMLQLS-LRR 532

  Fly   400 PQLDLVLVVPI------ASSLISLVLVVLFY 424
            .|.|.....|.      .|.:::||:....|
Human   533 LQADYASQAPFIVALSGTSEMLALVIGHFIY 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9903	NP_573132.1	YfeH	135..390	CDD:440154	69/287 (24%)
SLC10A3	XP_006724910.1	SBF	294..567	CDD:450274	71/273 (26%)