Protein Alignment S-Lap2 and Lap3

DIOPT Version :10

• Sequence 1: NP_729394.1
• Gene: S-Lap2 / 326209
• FlyBaseID: FBgn0052351
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_077754.3
• Gene: Lap3 / 66988
• MGIID: 1914238
• Length: 519
• Species: Mus musculus
• Alignment Length: 502
• Identity: 221/502 - (44%)
• Similarity: 313/502 - (62%)
• Gaps: 19/502 - (3%)

  Fly    50 SRGLVVGVYADEEDKNDAGILTPTGWKYNVQKTHGRLLEVLRMSGPMPKRGETRLLFAVEPERVP 114
            ::|||:|:||.::| :|....|..|..:| :...|:|.|:|.:|||..|.|:||..:.:..:
Mouse    33 TKGLVLGIYAKDKD-DDLPQFTSAGESFN-KLVSGKLREMLNISGPPLKAGKTRTFYGLHQD--- 92

  Fly   115 YYSAVAVIGLGKECLGYNPYEVLDEQKEAIRRSVADACRILAELDTDRIEVENCGHAESAAEGAA 179
             :.:|.|:||||...|.:..|...|.||.||.:||..||.:.:|:...:||:.||.|::|||||.
Mouse    93 -FPSVVVVGLGKRSAGVDDQENWHEGKENIRAAVAAGCRQVQDLELPSVEVDPCGDAQAAAEGAV 156

  Fly   180 LGIWIYQELRDPKRRISVPSIDLYATKDEICDIEGWRIGLQKAAAQNLTRQLQEMPSNLLTPTAF 244
            ||::.|.:|:. |::::| |..|:.:.    |:|.|..|:..|:.|||.|.|.|.|:|.:|||.|
Mouse   157 LGLYEYDDLKQ-KKKVAV-SAKLHGSG----DLEAWEKGVLFASGQNLARHLMESPANEMTPTRF 215

  Fly   245 AQNVVEVLCKSG---VNVEVKVEGWAESQSMHAFLAVGKASCEPPIFLELSYYGT-CAEERPIVL 305
            |: ::|...||.   ..|.::.:.|.|.|.|.:||:|.|.|.|||:|||:.|.|: .|.|.|:|.
Mouse   216 AE-IIEKNLKSASSKTKVHIRPKSWIEEQEMGSFLSVAKGSEEPPVFLEIHYMGSPNATEAPLVF 279

  Fly   306 VGQGVTYDAGGLCLKEKQELFHMRGDMTGAAVVVATCRAVAGLRLPVNIRGLIPLCENVIGCNSF 370
            ||:|:|:|:||:.:|....:..||.||.|||.:.:...:.|.|.||:||.||.|||||:....:.
Mouse   280 VGKGITFDSGGISIKASANMDLMRADMGGAATICSAIVSAAKLNLPINIIGLAPLCENMPSGKAN 344

  Fly   371 RPGDMVKSMNGKTIEVQCTDHEDVLVLADALLYGQNFCPKCIIDIGTCSGYMRQALDEAACGVFT 435
            :|||:|::.|||||:|..||.|..|:|||||.|...|.||.||:..|.:|.|..||...|.||||
Mouse   345 KPGDVVRARNGKTIQVDNTDAEGRLILADALCYAHTFNPKVIINAATLTGAMDVALGSGATGVFT 409

  Fly   436 NSEILWQQIKHASMHTGDRVWRFPLWNYYSKAVRAGGRSDVQNYGIGRGGRPCKAAAFLREFVPC 500
            ||..||.::..||:.|||||||.||:.:|::.|.....:||.|.|..|....|.|||||||||..
Mouse   410 NSSWLWNKLFEASVETGDRVWRMPLFEHYTRQVIDCQLADVNNLGKYRSAGACTAAAFLREFVTH 474

  Fly   501 GQWMHIDATNVMITRGDEFEYLREGMAGRPTRTLIEFIAQSICKDTA 547
            .:|.|:|...|| |..||..|||:||:||||||||||:.: ..||::
Mouse   475 TKWAHLDIAGVM-TNKDEIPYLRKGMSGRPTRTLIEFLLR-FSKDSS 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S-Lap2	NP_729394.1	Peptidase_M17_N	54..189	CDD:426984	51/134 (38%)
		Peptidase_M17	227..533	CDD:459978	148/309 (48%)
Lap3	NP_077754.3	Peptidase_M17	33..511	CDD:238247	218/491 (44%)