DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32344 and Rs1

DIOPT Version :9

Sequence 1:	NP_612028.4	Gene:	CG32344 / 326208	FlyBaseID:	FBgn0052344	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_001286188.1	Gene:	Rs1 / 44087	FlyBaseID:	FBgn0021995	Length:	782	Species:	Drosophila melanogaster

Alignment Length:	772	Identity:	200/772 - (25%)
Similarity:	328/772 - (42%)	Gaps:	154/772 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 NDAGTSDRGADILK-----------SKSKKNKSG------------------------GFQSMGL 46
            :|....|...|.||           ||.||.|:|                        .|..|.|
  Fly   100 SDGSEIDLSEDELKHDNLRLREKKESKKKKKKAGEEDEEDEGEKMQFADTVEANEQITSFYQMNL 164

  Fly    47 GFELIKGITKRGYKVPTPIQRKTIPLILEGRDVVAMAKTGSGKTACFLIPLFEKLQRREPTKGA- 110
            ...|::.|...||..|||||..|||:.|.|||:...|.||:||||.:::|..|:|..|.....|
  Fly   165 SRPLMRAIGVLGYIYPTPIQASTIPVALLGRDICGCAATGTGKTAAYMLPTLERLLYRPLNNKAI 229

  Fly   111 -RALILSPTRELAVQTYKFIKELGRFMELKSILVLGGDSMDSQFSAIHTCPDVIVATPGRFL-HL 173
             |.|:|.|||||..|.|:..|:|.:|..:...|.:||..:.:|.:.:...||:::|||||.: |:
  Fly   230 TRVLVLVPTRELGAQVYQVTKQLCQFTTIDVGLAIGGLDVKAQEAVLRQNPDIVIATPGRLIDHI 294

  Fly   174 CVEMDLKLNSIEYVVFDEADRLFEMGFGEQLNETLHRLPSSRQTVMFSATLPKLLVEFARAGLND 238
            .......|:|||.::.|||||:.:..|.||:.|.::....:|||::||||:.:.:.:.|...|:.
  Fly   295 KNTPSFTLDSIEVLILDEADRMLDEYFAEQMKEIINSCCKTRQTMLFSATMSEQVKDLAAVSLDK 359

  Fly   239 PVLIRLDVESKLPDALALKFLYCRPD---DRYTALVVLLKYVIPVQSQTVVFAGTQHHVELISYI 300
            |:.:.::...::...|..:|:..|.|   ||...|..|:....  ....:||..|:.....:..:
  Fly   360 PIKVFVNNNQQVAFNLRQEFIRIREDKEGDREPILASLICRTF--HDHCMVFVQTKKQAHRLHIL 422

  Fly   301 LTEAGISNASVYSSLDPAARKINTAKFVNKKVSVLIVTDVAARGIDIPSLDFVVNLHFPGKPKLF 365
            |...|:....::.:|....|..:..||..:::.|||.|||||||:||..:..|:|...|...:.:
  Fly   423 LGLLGVRAGELHGNLTQQQRLESLKKFKEEQIDVLIATDVAARGLDIVGVKTVINFVMPITTEHY 487

  Fly   366 VHRVGRCARAGRTGTAYSIVSTDDTAHLLDLHLFLNRPFNIHDSSALGTIPQDLLEEEHLTVTDI 430
            :|||||.|||||.|.:.|:....:...:.|  :..|....|.:.    .||.:::|:....:|.:
  Fly   488 IHRVGRTARAGRAGISVSLAGEKERKIVKD--IIKNAESTIKNR----IIPPEIIEKYRNKLTSL 546

  Fly   431 KKSHHIAGVLRTSENAYKKYLSSRPVASTDANARVKKIKFFALKPLEDFFTAAPVLAQAAEASGQ 495
            :..         .:|...:..:.|.:|.|:  .::.|             |...:|.|..|..|.
  Fly   547 EPE---------IQNILDEEQAERQLAKTE--QQLSK-------------TERKLLGQTNERRGW 587

  Fly   496 STESQAKVSAAERKLQEEKHDILVKMRSFRPGGTVFELNTTQKSTQFIVMKEKRMQHA------- 553
            ....|      :|:.::::..:.........||         |.......|.||.::.
  Fly   588 FQTKQ------QREAEKDRLALTTGDEDKASGG---------KGKGKTAGKRKRPEYGGDGEDGP 637

  Fly   554 ---EVINKFRQQRAEEDIDEEKKTIEALNPSSGRMPTADEEAISSTFNKVVAPKRLQNMDALYKD 615
               ::..|..:::.||   ..|||.|.|         |.|.|:          |.::.:..:...
  Fly   638 PVKDLEAKRNKKKKEE---PRKKTPEQL---------AKERAM----------KEIEKVSLVRAK 680

  Fly   616 KPKKKKR--KINSKDEDHYVPYQSADKHTEDGLAINNFERQAQNAEFSVSDRDL---------SQ 669
            ..|.:||  |:.:..|.|           ..|.:....:|:...:.|:....|:         |:
  Fly   681 MAKLRKRPGKLGAATEVH-----------RSGASDGKPKRRGGQSAFTNDLTDVSRGGALRLRSE 734

  Fly   670 EVKHKPGLKKWDRI--KKKMVSVQ-DPRANKIRTESGAWIPASFKTGRYAEWKEKSK 723
            ..:|    ||..:|  |||..||: ..:|.|.:...|    .:|...|:|: |:|.|
  Fly   735 ANRH----KKMTKIAAKKKASSVKLTNKAGKNKFNKG----KNFGGPRHAK-KDKKK 782

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32344	NP_612028.4	DEADc	41..243	CDD:238167	79/204 (39%)
		DEXDc	54..243	CDD:214692	75/191 (39%)
		HELICc	263..384	CDD:238034	40/123 (33%)
		DBP10CT	666..721	CDD:285373	18/66 (27%)
Rs1	NP_001286188.1	PTZ00424	148..537	CDD:185609	128/396 (32%)
		DEADc	159..364	CDD:238167	79/204 (39%)
		Helicase_C	393..498	CDD:278689	33/106 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451636
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D268859at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24031
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950