DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32344 and CG10333

DIOPT Version :9

Sequence 1:	NP_612028.4	Gene:	CG32344 / 326208	FlyBaseID:	FBgn0052344	Length:	827	Species:	Drosophila melanogaster
Sequence 2:	NP_609888.2	Gene:	CG10333 / 35112	FlyBaseID:	FBgn0032690	Length:	822	Species:	Drosophila melanogaster

Alignment Length:	462	Identity:	139/462 - (30%)
Similarity:	226/462 - (48%)	Gaps:	57/462 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 DNDAGTSDRGADILKSKSKKNKSGG--------FQSMGLGFELIKGITKRGYKVPTPIQRKTIPL 72
            :||..| :|...|.:........||        :...|...|:|..|.|.|||.||||||:.||:
  Fly   364 ENDEMT-ERDWRIFREDYNVTIKGGRIPNPIRSWNESGFPKEIIDIIDKVGYKEPTPIQRQAIPI 427

  Fly    73 ILEGRDVVAMAKTGSGKTACFLIPLFE------KLQRREPT-KGARALILSPTRELAVQTYKFIK 130
            .|:.||::.:|:||||||..|||||..      |::|.|.. :|..|:|::||||||.|..:...
  Fly   428 GLQNRDIIGVAETGSGKTLAFLIPLLSWIQSLPKIERLEDVDQGPYAIIMAPTRELAQQIEEETT 492

  Fly   131 ELGRFMELKSILVLGGDSMDSQFSAIHTCPDVIVATPGRFLHLCVEMDLKLNSIEYVVFDEADRL 195
            :.|:.:.:::::|:||.|.:.|...:....::::|||||.:.:.....|.||...|:|.|||||:
  Fly   493 KFGQPLGIRTVVVVGGLSREEQGFRLRLGCEIVIATPGRLIDVLENRYLVLNQCTYIVLDEADRM 557

  Fly   196 FEMGFGEQLNETLHRLPSS-------------------------RQTVMFSATLPKLLVEFARAG 235
            .:|||...:.:.|..:|.:                         ||||||:||:|..:...||..
  Fly   558 IDMGFEPDVQKILEYMPVTNLKPDTEEAEDETKLMENFYTKKKYRQTVMFTATMPPAVERLARTY 622

  Fly   236 LNDPVLIRLDVESKLPDALALKFLYC--RPDDRYTALVVLLKYVIPVQSQTVVFAGTQHHVELIS 298
            |..|..:.:....| |.....:.:|.  ..|.|...:.:|.:.:.|   ..::|...:...::::
  Fly   623 LRRPATVYIGSVGK-PTERTEQIVYMMGENDKRKKLMEILSRKIDP---PVIIFVNQKKGADVLA 683

  Fly   299 YILTEAGISNASVYSSLDPAARKINTAKFVNKKVSVLIVTDVAARGIDIPSLDFVVNLHFPGKPK 363
            ..|.:.|.::.:::.......|:...|...:....:|:.||||.|||||..:..|:|.......:
  Fly   684 KGLEKLGYNSCTLHGGKGQEQREYALAALKSGAKDILVATDVAGRGIDIKDVSLVINYDMAKTIE 748

  Fly   364 LFVHRVGRCARAGRTGTAYSIVSTDDTAHLLDLHLFLNRPFNIHDSSALGTIPQDLL---EEEHL 425
            .:.||:||..|||:||.|.|.|:.||:|...||...::       :|.:.|.|.:|:   |.:|.
  Fly   749 DYTHRIGRTGRAGKTGCAISFVTKDDSALFYDLKQCVS-------ASPVSTCPPELMNHPEAQHK 806

  Fly   426 TVTDIKK 432
            ..|.:.|
  Fly   807 PGTVVTK 813

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32344	NP_612028.4	DEADc	41..243	CDD:238167	83/233 (36%)
		DEXDc	54..243	CDD:214692	80/220 (36%)
		HELICc	263..384	CDD:238034	31/120 (26%)
		DBP10CT	666..721	CDD:285373
CG10333	NP_609888.2	DEADc	396..629	CDD:238167	83/232 (36%)
		DEXDc	409..632	CDD:214692	80/222 (36%)
		Helicase_C	651..761	CDD:278689	26/112 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451649
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840